为了降低甲状腺肿瘤的误诊率和漏诊率,提出将甲状腺肿瘤的SPECT图像和B超图像进行多模异机融合,提供涵盖功能信息和结构信息的融合后图像,为手术规划和放射治疗提供依据.配准是融合的前提,针对2种成像模式的不同特点,采用阈值方法和图割方法提取轮廓并填充为二值图像,建立仿射变换模型对待配准图像进行变换,将混合蛙跳算法引入基于特征的配准过程中,将局部区域的二值图像的互信息量作为适应度函数以获取水平平移量、垂直平移量和旋转角度的全局最优解.实验表明,该算法具有参数少、配准精度高、鲁棒性强等特点,为2种模式图像的融合奠定了基础.
[1] 赵海峰, 姚丽莎, 罗斌, ZHAO Haifeng, YAO Lisha, LUO Bin. 改进的人工鱼群算法和Powell法结合的医学图像配准 [J]. 西安交通大学学报 2011.
[2] 谭志国, 鲁敏, 任戈, 刘顺发, Tan Zhiguo, Lu Min, Ren Ge, Liu Shunfa. 匹配与姿态估计的粒子群优化算法 [J]. 中国图象图形学报 2011.
[3] 李登旺, 王洪君, 尹勇, LI Deng-Wang, WANG Hong-Jun, YIN Yong. 基于边缘保护多尺度空间的医学图像配准方法 [J]. 模式识别与人工智能 2011.doi:10.3969/j.issn.1003-6059.2011.01.015
[4] Suh, J.W., Kwon, O.-K., Scheinost, D., Sinusas, A.J., Cline, G.W., Papademetris, X.. CT-PET weighted image fusion for separately scanned whole body rat [J]. Medical Physics 2012, 1(1).
[5] Delibasis KK, Asvestas PA, Matsopoulos GK. Automatic point correspondence using an artificial immune system optimization technique for medical image registration. [J]. Computerized Medical Imaging and Graphics: The Official Jounal of the Computerized Medical Imaging Society 2011, 1(1).
[6] Freiman M, Werman M, Joskowicz L. A curvelet-based patient-specific prior for accurate multi-modal brain image rigid registration. [J]. Medical image analysis 2011, 1(1).
[7] Mohammed Khader, A. Ben Hamza. An information-theoretic method for multimodality medical image registration [J]. Expert Systems with Application 2012, 5(5).
[8] Ashburner J, Friston KJ. Diffeomorphic registration using geodesic shooting and Gauss-Newton optimisation. [J]. NeuroImage 2011, 3(3).
[9] Papazov, C., Burschka, D.. Stochastic global optimization for robust point set registration [J]. Computer vision and image understanding: CVIU 2011, 12(12).
[10] Xu N, Ahuja N, Bansal R. Object segmentation using graph cuts based active contours [J]. Computer vision and image understanding: CVIU 2007, 3(3).
[11] Muzaffar M. Eusuff, Kevin E. Lansey. Optimization of Water Distribution Network Design Using the Shuffled Frog Leaping Algorithm [J]. Journal of Water Resources Planning and Management 2003, 3(3).
[12] 崔文华, 刘晓冰, 王伟, 王介生. 混合蛙跳算法研究综述 [J]. 控制与决策 2012.
[13] ELBELTAGI E, HEGAZY T, GRIERSON D. Comparison among five evolutionary-based optimization algorithm [J]. Advanced Engineering Informaties 2001, 19(01).
