微波辐射一锅法合成N-(4-芳基噻唑-2-基)-腙类化合物

  • 李记太 ,
  • 张冬暖 ,
  • 刘卉闵 ,
  • 宋亚丽
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  • 1.河北大学化学与环境科学学院,河北保定,071002; 2.河北大学化学与环境科学学院,河北保定071002;河北农业大学理学院,河北保定071001; 3.河北农业大学理学院,河北保定,071001; 4.河北大学药学院,河北保定,071002

网络出版日期: 2012-05-25

基金资助

河北省教育厅计划项目,保定市科技研究与发展指导计划项目

Microwave-assisted efficient one-pot synthesis of N- (4-arylthiazol-2-yl) hydrazones

  • LI Ji-tai ,
  • ZHANG Dong-nuan ,
  • LIU Hui-min ,
  • SONG Ya-li
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Online published: 2012-05-25

摘要

在微波辐射下,以异丙醇作溶剂,以醛(或酮)、氨基硫脲和溴代苯乙酮进行一锅3组分反应,探讨了溶剂和微波功率对反应的影响,确定了最佳反应条件,并合成了一系列N-(4-芳基噻唑-2-基)-腙类化合物,反应时间5~10 min,产率86%~95%.

本文引用格式

李记太 , 张冬暖 , 刘卉闵 , 宋亚丽 . 微波辐射一锅法合成N-(4-芳基噻唑-2-基)-腙类化合物[J]. 河北大学学报(自然科学版), 2012 , 32(3) : 261 -264,290 . DOI: 10.3969/j.issn.1000-1565.2012.03.008

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