研究了分别以不同的分子筛以及草酸、磷酸、盐酸等酸改性的Hβ分子筛为催化剂,由吡咯和乙酸酐合成乙酰基吡咯的Friedel-Crafts酰基化反应.发现磷酸改性的Hβ分子筛催化剂的活性最高,并对催化剂用量、反应温度、反应时间等反应条件进行了优化,确定了最佳反应条件:反应温度70℃、催化剂用量0.4 g、反应时间5 h,此时,吡咯的转化率为97.4%,2-乙酰基吡咯的选择性为76.7%,乙酰基吡咯的总选择性为93.8%.同时,稳定性实验证明磷酸改性的Hβ分子筛具有良好的稳定性.
[1] 马志广, 邹于梅, 张爱平, MA Zhi-guang, ZOU Yu-mei, ZHANG Ai-ping. ZSM-5分子筛负载钯-壳聚糖配合物催化苯丙酮加氢的反应动力学 [J]. 河北大学学报（自然科学版） 2008.doi:10.3969/j.issn.1000-1565.2008.05.012
[2] DECK R E, POKORNY J, CHANG S S. Isolation and identification of volatile compounds from potato chips [J]. Journal of Food Science 1973, 38(02).
[3] MASAHIRO I, MASAAKI M. Thermally irreversible photochromic systems.Reversible photocyclization of diarylethene derivatives [J]. Journal of Organic Chemistry 1988, 53(04).
[4] 樊贵宝, 明阳福, 樊美公. 二芳杂环基乙烯的合成及其光致变色反应研究 [J]. 有机化学 1994, 14(06).
[5] Reddy PR., Kulkarni SJ., Subrahmanyam M.. Vapour phase acylation of furan and pyrrole over zeolites [J]. Catalysis Letters 1998, 1/2(1/2).
[6] Vasco F.D. Alvaro, Amadeu F. Brigas, Eric G. Derouane. Mild liquid-phase Friedel-Crafts acylation of heteroaromatic compounds over zeolite Beta [J]. Journal of molecular catalysis, A. Chemical 2009, 1/2(1/2).
[7] BAI Guoyi, DOU Haiyang, QIU Mande. Friedel-Crafts hydroxyalkylation of anisole over oxalic acid modified Hβ zeolite [J]. Catalysis Letters 2010, 138(3-4).
[8] Kanakkampalayam Krishnan, Inguva Sudarsan Kumar, Muthiahpillai Palanichamy, Velayutham Murugesan. Liquid phase alkylation of phenol with 4-hydroxybutan-2-one in the presence of modified zeolite HBEA [J]. Applied Catalysis, A. General: An International Journal Devoted to Catalytic Science and Its Applications 2003, 1/2(1/2).
[9] 白国义, 窦海洋, 樊欣欣, 王海龙, 牛立博, BAI Guo-yi, DOU Hai-yang, FAN Xin-xin, WANG Hai-long, NIU Li-bo. 磷酸改性的Hβ分子筛催化合成对甲氧基苯乙酮 [J]. 精细化工 2009.
