建立了以苄基三甲基碘化铵为内标测定白藜芦醇和白藜芦醇苷的毛细管区带电泳方法,在优化的分离条件下,两者在7 min内可基线分离,检出限均为1.25×10-4 g/L,线性动态范围分别是4.88×10-4 g/L～0/.31 g/L和5.37×10-4g/L～0.34 g/L,样品的加标回收率为95.44%和97.75%.
[1] Juan SH, Cheng TH, Lin HC, Chu YL, Lee WS. Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells. [J]. Biochemical Pharmacology 2005, 1(1).
[2] JANG M S, CAI L N, GEORGE O. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes [J]. Science 1997, 275.
[3] Stewart JR, Artime MC, O'Brian CA. Resveratrol: A candidate nutritional substance for prostate cancer prevention [J]. The Journal of Nutrition 2003, 7 suppl(7 suppl).
[4] Stivala LA otta.unipv.it, Savio M, Carafoli F, Perucca P, Bianchi L, Maga G, Forti L, Pagnoni UM, Albini A, Prosperi E, Vannini V. Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol. [J]. The Journal of biological chemistry 2001, 25(25).
[5] Jimenez JB, Orea JM, Montero C, Urena AG, Navas E, Slowing K, Gomez-Serranillos MP, Carretero E, De Martinis D. Resveratrol treatment controls microbial flora, prolongs shelf life, and preserves nutritional quality of fruit [J]. Journal of Agricultural and Food Chemistry 2005, 5(5).
[6] Hebbar V, Shen G, Hu R, Kim BR, Chen C, Korytko PJ, Crowell JA, Levine BS, Kong AN. Toxicogenomics of resveratrol in rat liver. [J]. Life sciences 2005, 20(20).
[7] RUDOLF J L, RESURRECCION A V A, SAALIA F K. Development of a reverse-phase high-performance liquid chromatography method for analyzing trans-resveratrol in peanut kernels [J]. Food Chemistry 2005, 89.
[8] LIN C H, CHEN Y H. On-line identification of trans-and cis-resveratrol by nonaqueous capillary electrophoresis/fluorescence spectroscopy at 77k [J]. ELECTROPHORESIS 2001, 22.
