在微波照射的条件下,用苯甲醛、丙二酸为原料,以乙酸铵为催化剂在无溶剂的条件下进行缩合反应,直接合成(E)-肉桂酸.反应时间6 min,反应温度110 ℃,产率为95%, 产物纯度为98.5%.
[1] 章思规. 精细有机化学品技术手册 [M]. 北京:科学出版社 1992.
[2] 李述文, 范如霖. 实用有机化学手册 [M]. 上海:上海科学技术出版社 1981.
[3] Maryam Mirza-Aghayan, Majid M. Heravi. Chromium Trioxide on H-Y Zeolite: Rapid Oxidation of Alcohols to Carbonyl Compounds in Solventless System Using Microwaves [J]. Synthetic Communications 1999, 5(5).
[4] Bogdal D., Lukasiewicz M.. Microwave-assisted oxidation of alcohols using aqueous hydrogen peroxide [J]. Synlett 2000, 1(1).
[5] ABDOL R H, SHADPOUR E M. A repid and convenient synthesis of oximes in dry media under microwave irradition [J]. Journal of Chemical Research 1999.
[6] VAISHALI C, MANOBZYOT B. Deoximation by pyridinium chlorochromate under microwave irradiation [J]. Journal of Chemical Research 1999.
[7] T.S.Li. A facile procedure for the oxidative coupling of 2-naphthol and 2-naphthalenethiol in solid state [J]. 1998.
[8] Kumar HMS., Anjaneyulu S., Yadav JS., Subbareddy BV.. Non solvent reaction: Ammonium acetate catalyzed highly convenient preparation of trans-cinnamic acids. [J]. Synthetic Communications 1998, 20(20).