A series of 2-aryl-1,3-benzoxathiin-4-ones were synthesized by aromatic aldehyde and thiosalicylic acid under microwave irradiation for 5 min.The reaction is fast,simple and has high yield.The structures of the synthesized compounds were characterized by IR,NMR,MS spectra and elemental analysis.Antibacterial(Escherichia coli and Dysentery bacillus)activities of the compounds against Escherichia coli and Dysentery bacillus were evaluated.The results showed that 2-aryl-1,3-benzoxathiin-4-ones had good antibacterial activity.
FENG Junna
,
PENG Shaohui
,
CUI Penglei
,
CHEN Hua
,
LI Xiaoliu
. Microwave assisted synthesis and antibacterial study of 2-aryl-1,3-benzoxathiin-4-ones[J]. Journal of Hebei University(Natural Science Edition), 2016
, 36(4)
: 396
-401
.
DOI: 10.3969/j.issn.1000-1565.2016.04.011
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