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    25 May 2025, Volume 45 Issue 3
    Hub location strategy for ensuring service capability of supply chain in Beijing-Tianjin-Hebei region under disruption risk
    CHEN Yanju, YIN Fanghao, LIU Yankui
    2025, 45(3):  225-234.  DOI: 10.3969/j.issn.1000-1565.2025.03.001
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    Service capacity guarantee under the disruption risk of supply chain is a key challenge for the coordinated development of Beijing-Tianjin-Hebei region. Aiming at the characteristics of both random and fuzzy uncertainty of transportation time, this paper proposes an equilibrium optimization model of single allocation hub location based on ambiguous probability distribution. Firstly, by introducing the equilibrium value-at-risk constraint, the uncertainty of transportation time is quantified in the joint form of credibility distribution and probability distribution to ensure that the path transportation time meets the service level requirement. Secondly, the equilibrium optimization model is constructed to minimize the total average transportation time. It is equivalently converted to mixed integer linear programming to realize the efficient solution of the model under trapezoidal fuzzy parameters and normal probability distribution. The case study based on 15 nodes in Beijing-Tianjin-Hebei region shows that compared with the traditional stochastic optimization method, the proposed method can optimize the hub location scheme under dual uncertainty, and the sensitivity of the optimal hub location to the change of confidence level and transportation time limit is significantly improved.The research results provide effective decision support for- DOI:10.3969/j.issn.1000-1565.2025.03.001京津冀供应链中断风险下保障服务能力的枢纽选址策略陈艳菊,殷方浩,刘彦奎(河北大学 数学与信息科学学院,河北 保定 071002)摘 要:供应链中断风险下的服务能力保障是京津冀协同发展的关键挑战.针对运输时间兼具随机与模糊双重不确定性的特征,提出一种基于非精确概率分布的单分配枢纽选址平衡优化模型.首先,通过引入平衡风险值约束,将运输时间的不确定性用可信分布与概率分布的联合形式进行量化,确保路径运输时间满足服务水平要求;其次,以总平均运输时间最小化为目标,构建平衡优化模型,并在梯形模糊参数与正态概率分布下等价转换为混合整数线性规划以实现高效求解.京津冀地区15个节点的案例研究表明:相较于传统随机优化方法,本文方法在双重不确定性下能够有效优化枢纽选址方案,最优枢纽位置对置信水平与运输期限的变化敏感度显著提升.研究结果为复杂不确定环境下区域物流网络优化提供了有效的决策支持.关键词:枢纽选址;平衡优化;双重不确定性;非精确概率分布;京津冀供应链中图分类号:C934 文献标志码:A 文章编号:1000-1565(2025)03-0225-10Hub location strategy for ensuring service capability of supply chain in Beijing-Tianjin-Hebei region under disruption riskCHEN Yanju, YIN Fanghao, LIU Yankui(College of Mathematics and Information Science, Hebei University, Baoding 071002, China)Abstract: Service capacity guarantee under the disruption risk of supply chain is a key challenge for the coordinated development of Beijing-Tianjin-Hebei region. Aiming at the characteristics of both random and fuzzy uncertainty of transportation time, this paper proposes an equilibrium optimization model of single allocation hub location based on ambiguous probability distribution. Firstly, by introducing the equilibrium value-at-risk constraint, the uncertainty of transportation time is quantified in the joint form of credibility distribution and probability distribution to ensure that the path transportation time meets the service level requirement. Secondly, the equilibrium optimization model is constructed to minimize the total average transportation time. It is equivalently converted to mixed integer linear programming to realize the efficient solution of the model under trapezoidal fuzzy parameters and normal probability distribution. The case study based on 15 nodes in Beijing-Tianjin-Hebei region shows that compared with the traditional stochastic optimization method, the proposed method can optimize the hub location scheme under dual uncertainty, and the sensitivity of the optimal hub location to the change of confidence level and transportation time limit is significantly improved.The research results provide effective decision support for- 收稿日期:2024-05-04;修回日期:2024-12-27 基金项目:河北省社科基金资助项目(HB21YJ029) 第一作者:陈艳菊(1978—),女,河北大学副教授,主要从事随机优化、平衡优化及其应用方向研究.E-mail:yanjuchen@hbu.edu.cn 通信作者:刘彦奎(1963—),男,河北大学教授,博士生导师,主要从事不确定性最优化理论方向研究.E-mail:yliu@hbu.edu.cn 第3期陈艳菊等:京津冀供应链中断风险下保障服务能力的枢纽选址策略河北大学学报(自然科学版) 第45卷regional logistics network optimization in complex and uncertain environment.
    Long-distance pipe-roof group jacking pipeline deviation and closure attitude analysis
    ZHANG Chenhao, CHEN Siming, LUO Song, GUAN Zhenchang, HUANG Jinfeng, JIA Pengjiao
    2025, 45(3):  235-243.  DOI: 10.3969/j.issn.1000-1565.2025.03.002
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    Pipe-roof structures are frequently utilized in sensitive projects, such as those involving underpasses beneath existing railways and subways, due to their effectiveness in controlling ground disturbance. During the jacking process of pipe-roof installation, deviations may occur due to soil parameters and construction parameters. Excessive deviations can compromise the supporting efficacy of the pipe-roof structure. However, there exists a relative paucity of research specifically addressing deviations during pipe-roof jacking. Based on the transfer passage project, this paper records in real-time the attitude changes during the jacking process of steel pipes, and studies the deviation of the jacked pipeline as well as the closure attitude of pipe sections at different cross-sections. The findings are summarized- DOI:10.3969/j.issn.1000-1565.2025.03.002长距离管幕群顶进管道偏差及闭合姿态分析张晨浩1,陈思明2,罗嵩2,关振长3,黄金峰2,贾鹏蛟1(1.苏州大学 轨道交通学院,江苏 苏州 215137;2.中铁南方投资集团有限公司,广东 深圳 518052;3.福州大学 土木工程学院,福建 福州 350108)摘 要:管幕结构因能有效控制地层扰动而常被用于下穿铁路、地铁等敏感工程,群管在顶进过程中,因受土层参数、掘进参数等影响而发生偏差,若偏差过大将影响管幕结构支护效果.依托某换乘通道工程,实时记录了钢管顶进过程中的姿态变化,研究了顶进管道的偏差以及不同断面处管节的闭合姿态.研究表明:1)77.2%钢管偏差在40 mm(钢管直径的5%)及以内,且锁口在垂直于管幕群的方向约束效应更强.随着顶进距离的增大,锁口的约束效应会减弱;2)刚性连接钢管穿越洞口和中段MJS加固区时,表现出明显的刚度效应,积累较大偏差,约70%的顶管出现右偏趋势;3)在顶管的前段整体姿态有波动但仍保持平稳;中段偏差逐渐放大,但最大值控制在65 mm以内,靠近接收井处下排管幕群经过纠偏已经基本归位(竖向偏差均控制在40 mm以内,76.9%钢管水平偏差控制在40 mm以内),上排管幕群偏差平均值在40 mm以内.关键词:管幕;偏差;闭合姿态;约束效应;刚度效应中图分类号:TU447 文献标志码:A 文章编号:1000-1565(2025)03-0235-09Long-distance pipe-roof group jacking pipeline deviation and closure attitude analysisZHANG Chenhao1, CHEN Siming2, LUO Song2, GUAN Zhenchang3, HUANG Jinfeng2, JIA Pengjiao1(1. College of Rail Transportation, Soochow University, Suzhou 215137, China; 2. China Railway South Investment Group Co., Ltd., Shenzhen 518052, China; 3. College of Civil Engineering, Fuzhou University, Fuzhou 350108, China)Abstract: Pipe-roof structures are frequently utilized in sensitive projects, such as those involving underpasses beneath existing railways and subways, due to their effectiveness in controlling ground disturbance. During the jacking process of pipe-roof installation, deviations may occur due to soil parameters and construction parameters. Excessive deviations can compromise the supporting efficacy of the pipe-roof structure. However, there exists a relative paucity of research specifically addressing deviations during pipe-roof jacking. Based on the transfer passage project, this paper records in real-time the attitude changes during the jacking process of steel pipes, and studies the deviation of the jacked pipeline as well as the closure attitude of pipe sections at different cross-sections. The findings are summarized- 收稿日期:2024-09-02;修回日期:2024-11-29 基金项目:国家自然科学基金资助项目(52108380) 第一作者:张晨浩(2001—),男,苏州大学在读硕士研究生,主要从事隧道工程方向研究.E-mail:chzhang616@stu.suda.edu.cn 通信作者:贾鹏蛟(1989—),男,苏州大学副教授,主要从事岩土与隧道工程方向研究.E-mail:pjjia@suda.edu.cn 第3期张晨浩等:长距离管幕群顶进管道偏差及闭合姿态分析河北大学学报(自然科学版) 第45卷as follows: 1)The majority(77.2%)of steel pipe deviations are confined within 40 mm(5% of the pipes diameter), indicating a high degree of precision. Furthermore, the locking mechanism exerts a more pronounced restraining effect in the direction perpendicular to the pipe-roof alignment. However, as the jacking distance increases, the constraining influence of the locking mechanism decreases. 2)When rigidly connected steel pipes pass through the tunnel opening and the middle section MJS reinforcement area, they exhibit a significant stiffness effect, accumulating a large deviation, with approximately 70% of the pipe jacking showing a rightward deviation trend. 3)In the initial section of the jacking process, although there are fluctuations in the overall attitude, it remains stable. In the middle section, the deviations within the pipe-roof gradually increase, but the maximum deviation is controlled within 65 mm. The lower pipe-roof group near the receiving shaft has been basically realigned after correction. The vertical deviation is controlled within 40 mm, and 76.9% of the steel pipes have horizontal deviations within 40 mm. The average deviation of the upper pipe-roof group is within 40 mm.
    Exploring the mechanism of isoniazid induced hypersensitivity reaction based on network toxicology
    ZHANG Peixiang, TIAN Shuoqi, WANG Yaojun, WU Lihong, LIANG Jianqin, LIU Zhongcheng
    2025, 45(3):  244-253.  DOI: 10.3969/j.issn.1000-1565.2025.03.003
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    The molecular mechanism of hypersensitivity reactions induced by isoniazid in the treatment of pulmonary tuberculosis was studied using network toxicology methods. Through queries on ChEMBL, STITCH, GeneCards, and OMIM databases, 45 potential targets related to isoniazid and hypersensitivity reactions were identified. Further screening using STRING and Cytoscape software highlighted 11 core targets, including BCL2, CYP3A4, and DRD2. GO and KEGG pathway analysis showed through DAVID and FUMA databases that isoniazid induced hypersensitivity reactions are mainly related to the enrichment of substance metabolism and endocrine pathways. Molecular docking using Autodock confirmed that isoniazid can stably bind to core targets such as BCL2. The results of this study suggest that isoniazid may - DOI:10.3969/j.issn.1000-1565.2025.03.003基于网络毒理学探究异烟肼诱发超敏反应的作用机制张沛祥1,田铄琪1,王姚俊1,武丽红2,梁建琴2,刘中成1(1.河北大学 药学院,河北省药物质量分析控制重点实验室,河北 保定 071002;2. 中国人民解放军总医院 第八医学中心,北京 100091)摘 要:基于网络毒理学的方法研究异烟肼治疗肺结核时引发超敏反应的分子机制,通过ChEMBL、STITCH、GeneCards和OMIM数据库查询,获得了与异烟肼和超敏反应相关的45个潜在靶点.进一步利用STRING和Cytoscape软件进行筛选,突出了包括BCL2、CYP3A4和DRD2在内的11个核心靶点.GO和KEGG通路分析通过DAVID和FUMA数据库显示,异烟肼诱导超敏反应主要与物质代谢和内分泌通路的富集有关.使用Autodock进行的分子对接验证了异烟肼与BCL2等核心靶标可以稳定结合.本研究结果表明,异烟肼可能通过调节细胞代谢及钙信号通路、胆碱能突触通路等影响超敏反应的发生和发展.此研究不仅为理解异烟肼诱导超敏反应的分子机制提供了理论依据,还为找寻预防其不良反应的方法奠定了基础.关键词:异烟肼;网络毒理学;分子对接;超敏反应中图分类号:R593.21 文献标志码:A 文章编号:1000-1565(2025)03-0244-10Exploring the mechanism of isoniazid induced hypersensitivity reaction based on network toxicologyZHANG Peixiang1, TIAN Shuoqi1, WANG Yaojun1, WU Lihong2, LIANG Jianqin2, LIU Zhongcheng1(1. Key Laboratory of Drug Quality Analysis and Control, College of Pharmacy, Hebei University, Baoding 071002, China; 2. The Eighth Medical Center, the General Hospital of the Chinese Peoples Liberation Army, Beijing 100091,China)Abstract: The molecular mechanism of hypersensitivity reactions induced by isoniazid in the treatment of pulmonary tuberculosis was studied using network toxicology methods. Through queries on ChEMBL, STITCH, GeneCards, and OMIM databases, 45 potential targets related to isoniazid and hypersensitivity reactions were identified. Further screening using STRING and Cytoscape software highlighted 11 core targets, including BCL2, CYP3A4, and DRD2. GO and KEGG pathway analysis showed through DAVID and FUMA databases that isoniazid induced hypersensitivity reactions are mainly related to the enrichment of substance metabolism and endocrine pathways. Molecular docking using Autodock confirmed that isoniazid can stably bind to core targets such as BCL2. The results of this study suggest that isoniazid may - 收稿日期:2024-08-21;修回日期:2025-02-25 基金项目:河北省自然科学基金资助项目(H2023201026;H2022201035);首都卫生发展科研专项(2024-2-5094) 第一作者:张沛祥(1999—),男,河北大学在读硕士研究生,主要从事超敏反应相关信号通路研究.E-mail:zhangpeixiang@stumail.hbu.edu.cn 通信作者:刘中成(1979—),男,河北大学教授,主要从事基因工程制药、分子毒理学方向研究.E-mail:liuzc@hbu.edu.cn梁建琴(1966—),女,中国人民解放军总医院主任医师,主要从事结核药物不良反应的研究.E-mail:ljqbj309@163.com 第3期张沛祥等:基于网络毒理学探究异烟肼诱发超敏反应的作用机制河北大学学报(自然科学版) 第45卷affect the occurrence and development of hypersensitivity reactions by regulating cellular metabolism, calcium signaling pathways, cholinergic synaptic pathways, and other pathways. This study not only provides a theoretical basis for understanding the molecular mechanism of isoniazid induced hypersensitivity reactions, but also lays the foundation for finding methods to prevent its adverse reactions.
    Efficacy and mechanism of the combined application of photodynamic antibacterial therapy and antibiotic on drug-resistant bacterial infection
    WANG Jianguo, XIE Jiaxin, KONG Feiyan, LI Yutong, ZHAO Zhanjuan
    2025, 45(3):  254-265.  DOI: 10.3969/j.issn.1000-1565.2025.03.004
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    Antibiotic therapy is currently the most critical means of controlling bacterial infections. However, antibiotic treatment is a major challenge due to increasing bacterial resistance. Photodynamic antimicrobial therapy(aPDT)uses reactive oxygen species to oxidize biological macromolecules to cause bacterial cell death, so bacteria are not susceptible to aPDT resistance. Antibiotics and aPDT are two different treatments for bacterial infections, both of which have good efficacy, but each has limitations. The combination of aPDT therapy with conventional antibiotics can achieve additive or synergistic therapeutic effects, and the inactivation effect of multidrug-resistant bacteria is more effective than that of a single approach. This article summarizes the current status of common drug-resistant bacterial infections in clinical practice, summarizes the therapeutic effects and mechanisms of different combinations of aPDT and antibiotics, and further points out the advantages, limitations and future development directions of combination therapy with aPDT and antibiotics, aiming to provide guidance for clinical application.- DOI:10.3969/j.issn.1000-1565.2025.03.004光动力抗菌疗法和抗生素联合应用对耐药菌感染的疗效及机制王建国1,谢佳欣2,孔飞雁3,李昱潼3,赵占娟3(1.河北大学附属医院,检验科,河北 保定 071000;2.河北大学 临床医学院,河北 保定 071000;3.河北大学 基础医学院,河北 保定 071000)摘 要:抗生素治疗是控制细菌感染的关键手段,但随着细菌耐药性的不断增强,抗生素治疗面临着巨大挑战.光动力抗菌疗法(photodynamlc antibacterial therapy,aPDT)利用活性氧氧化生物大分子导致细菌死亡,使细菌不易对aPDT产生耐药性.这2种针对细菌感染的不同治疗方式,均具有良好的疗效,但各自存在局限性.将aPDT治疗与常规抗生素联合使用可实现相加或协同治疗效果,对耐多药细菌的灭活效果超过单一方法.本文概述了临床常见耐药菌感染现况,对aPDT与抗生素不同组合在治疗上的效果和作用机制进行了总结,进一步指出了aPDT与抗生素联合治疗的优势、局限性以及未来发展方向,旨在为临床应用提供指导.关键词:光动力抗菌疗法;多重耐药菌;抗生素;联合治疗中图分类号:R378 文献标志码:A 文章编号:1000-1565(2025)03-0254-12Efficacy and mechanism of the combined application ofphotodynamic antibacterial therapy and antibioticon drug-resistant bacterial infectionWANG Jianguo1, XIE Jiaxin2, KONG Feiyan3, LI Yutong3, ZHAO Zhanjuan3(1. Clinical Lab, Affiliated Hospital of Hebei University,Baoding 071000,China;2. School of Clinical Medicine, Hebei University, Baoding 071000,China;3. School of Basic Medicine, Hebei University,Baoding 071000,China)Abstract: Antibiotic therapy is currently the most critical means of controlling bacterial infections. However, antibiotic treatment is a major challenge due to increasing bacterial resistance. Photodynamic antimicrobial therapy(aPDT)uses reactive oxygen species to oxidize biological macromolecules to cause bacterial cell death, so bacteria are not susceptible to aPDT resistance. Antibiotics and aPDT are two different treatments for bacterial infections, both of which have good efficacy, but each has limitations. The combination of aPDT therapy with conventional antibiotics can achieve additive or synergistic therapeutic effects, and the inactivation effect of multidrug-resistant bacteria is more effective than that of a single approach. This article summarizes the current status of common drug-resistant bacterial infections in clinical practice, summarizes the therapeutic effects and mechanisms of different combinations of aPDT and antibiotics, and further points out the advantages, limitations and future development directions of combination therapy with aPDT and antibiotics, aiming to provide guidance for clinical application.- 收稿日期:2024-08-21;修回日期:2024-10-25 基金项目:河北省自然科学基金资助项目(B2022201097);保定市科技计划项目(2494F002);国家级大学生创新基金项目(DC2024281) 第一作者:王建国(1976—),男,河北大学附属医院主任技师,主要从事临床医学检验及诊断方向研究.E-mail:wangjianguo2007@163.com 通信作者:赵占娟(1974—),女,河北大学副教授,博士,主要从事激光医学方向研究.E-mail:zhaozhanjuanv@163.com 第3期王建国等:光动力抗菌疗法和抗生素联合应用对耐药菌感染的疗效及机制河北大学学报(自然科学版) 第45卷
    Identification of OrCaM/OrCML gene family in Dongxiang wild rice and analysis of expression patterns under cold stress
    HUO Chenmin, XU Tianyun, WANG Jiao, ZHOU Shuo
    2025, 45(3):  266-277.  DOI: 10.3969/j.issn.1000-1565.2025.03.005
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    Since Dongxiang wild rice has better cold tolerance than cultivated rice, abundant cold resistance gene resources should be explored. In this study, members of the OrCaM/OrCML gene family from Dongxiang wild rice were identified at the whole-genome level and their physicochemical properties were analyzed, and the expression patterns of the OrCaM/OrCML gene family were investigated after cold stress. The results showed that there were 40 members of the OrCaM/OrCML family in Dongxiang wild rice, distributed in subgroups Ⅰ to Ⅶ in the phylogenetic tree. The members of each group had no other known functional domain except EF-hand. The types and quantities of promoter cis-elements of OrCaM/OrCML genes differed, 14 OrCaM/OrCML genes with either CRT/DRE or CM2 cis-elements were selected to examine their responses to cold stress. The results showed that OrCML1, OrCML6 and OrCML18 were the three most rapidly activated genes after cold stress. The results of this study provide a reference for studying the molecular mechanisms of the OrCaM/OrCML gene family response to cold stresses.- DOI:10.3969/j.issn.1000-1565.2025.03.005东乡野生稻OrCaM/OrCML基因家族鉴定与冷胁迫下表达模式分析霍晨敏1,许天运1,王娇2,周硕2(1. 河北经贸大学, 生物科学与工程学院, 河北 石家庄 050061; 2. 河北省农林科学院, 生物技术与食品科学研究所,河北省植物基因工程重点实验室, 河北 石家庄 050051)摘 要:东乡野生稻的耐冷性优于栽培稻,具有丰富的抗冷基因资源.本研究对东乡野生稻OrCaM/OrCML基因家族成员进行全基因组水平鉴定和理化性质分析,并探究家族成员冷胁迫后表达模式.结果显示,东乡野生稻中有40个OrCaM/OrCML家族成员,在系统进化树中分布于亚组Ⅰ~Ⅶ.各组成员除EF手单元,无其他已知功能的结构域.OrCaM/OrCML基因的启动子顺式元件种类和数量不同,笔者研究了14个具有CRT/DRE或CM2顺式元件的OrCaM/OrCML基因对冷胁迫的反应.结果表明,OrCML1、OrCML6和OrCML18属于冷胁迫后激活最快的3个基因.本结果对于研究OrCaM/OrCML基因家族响应冷胁迫的分子机制提供了参考.关键词:东乡野生稻; 钙调蛋白/类钙调蛋白; 保守基序; EF手单元; 启动子分析中图分类号:Q943 文献标志码:A 文章编号:1000-1565(2025)03-0266-12Identification of OrCaM/OrCML gene family in Dongxiang wild rice and analysis of expression patterns under cold stressHUO Chenmin1, XU Tianyun1, WANG Jiao2, ZHOU Shuo2(1. College of Bioscience and Engineering, Hebei University of Economics and Business, Shijiazhuang 050061,China;2. Hebei Key Laboratory of Plant Genetic Engineering, Institute of Biotechnology and Food Science, Hebei Academy of Agriculture and Forestry Sciences, Shijiazhuang 050051,China)Abstract: Since Dongxiang wild rice has better cold tolerance than cultivated rice, abundant cold resistance gene resources should be explored. In this study, members of the OrCaM/OrCML gene family from Dongxiang wild rice were identified at the whole-genome level and their physicochemical properties were analyzed, and the expression patterns of the OrCaM/OrCML gene family were investigated after cold stress. The results showed that there were 40 members of the OrCaM/OrCML family in Dongxiang wild rice, distributed in subgroups Ⅰ to Ⅶ in the phylogenetic tree. The members of each group had no other known functional domain except EF-hand. The types and quantities of promoter cis-elements of OrCaM/OrCML genes differed, 14 OrCaM/OrCML genes with either CRT/DRE or CM2 cis-elements were selected to examine their responses to cold stress. The results showed that OrCML1, OrCML6 and OrCML18 were the three most rapidly activated genes after cold stress. The results of this study provide a reference for studying the molecular mechanisms of the OrCaM/OrCML gene family response to cold stresses.- 收稿日期:2024-09-06;修回日期:2024-10-14 基金项目:河北省自然科学基金项目(C2024207001);河北省农林科学院现代农业科技创新专项(2022KJCXZX-SSS-5) 第一作者:霍晨敏(1978—), 女,河北经贸大学副教授,主要从事作物遗传育种方向研究. E-mail: huochenmin@hueb.edu.cn 第3期霍晨敏等:东乡野生稻OrCaM/OrCML基因家族鉴定与冷胁迫下表达模式分析河北大学学报(自然科学版) 第45卷
    Effects of UiO-66-SH on the growth and development of Brassica chinensis under arsenic and cadmium stresses in water-planting condition
    WANG Yan, CHEN Xinyi, ZHANG Lingli, WANG Xinyu, HE Tieguang, ZHANG Tuo
    2025, 45(3):  278-288.  DOI: 10.3969/j.issn.1000-1565.2025.03.006
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    We investigated the effects of UiO-66-SH on the growth and development of hydroponically grown Brassica chinensis under different concentrations of arsenic(As)and cadmium(Cd)stress. By measuring indicators such as the biomass of Pakchoi, the level of heavy metal enrichment, the content of malondialdehyde(MDA). and the activities of antioxidant enzymes, the adsorption mechanism of UiO-66-SH towards the combined pollution of arsenic and cadmium was analyzed.The results showed that the fresh and dry weights of both above-ground and below-ground parts of Brassica chinensis decreased with- DOI:10.3969/j.issn.1000-1565.2025.03.006砷镉胁迫下UiO-66-SH对水培小白菜生长发育的影响王焱1,陈芯怡1,张凌荔1,王鑫宇2,何铁光3,张拓2(1.西华师范大学 环境科学与工程学院,四川 南充 637000;2.南宁师范大学 环境与生命科学学院,广西 南宁 530001; 3. 广西农业科学院 农业资源与环境研究所,广西耕地保育重点实验室,广西 南宁 530007)摘 要:本文对砷(As)镉(Cd)胁迫下,UiO-66-SH对水培小白菜生长发育的影响进行了研究.通过测定小白菜的生物量、重金属富集水平、丙二醛(MDA)含量及抗氧化酶活性等指标,分析了UiO-66-SH对As、Cd复合污染的吸附机制.结果表明:随着As和Cd浓度的升高,小白菜地上部分和地下部分的鲜质量与干质量均有所下降,而UiO-66-SH的添加使下降趋势明显减弱.此外,UiO-66-SH添加后还促进了小白菜根长、株高及叶片展幅的生长,尤其在低质量浓度组处理下更为显著;在重金属富集方面,UiO-66-SH对水体中的As和Cd显示出良好的吸附性能,低质量浓度组和高质量浓度组中,小白菜对Cd的吸附率分别为69.5%和60.2%,对As的吸附率分别为71.1%和63.1%,显著降低了小白菜对As和Cd的吸收和富集,从而减少了重金属对小白菜的毒害作用;此外,UiO-66-SH通过降低MDA含量及SOD、POD、CAT、APX活性,缓解了氧化损伤,并且UiO-66-SH通过Zr—O—H和S—H键与As、Cd的络合作用,在材料表面形成了更加稳定的Zr—O—As和S—Cd键,从而实现了同步去除.研究表明,UiO-66-SH在缓解As和Cd胁迫对小白菜生长发育的抑制作用方面具有显著效果,是一种具有广阔应用前景的环境功能材料.关键词:砷镉胁迫;UiO-66-SH;小白菜;重金属吸附中图分类号:A53 文献标志码:A 文章编号:1000-1565(2025)03-0278-11Effects of UiO-66-SH on the growth and development of Brassica chinensis under arsenic and cadmium stresses in water-planting condition WANG Yan1, CHEN Xinyi1, ZHANG Lingli1, WANG Xinyu2, HE Tieguang3, ZHANG Tuo2(1.College of Environmental Science and Engineering, China West Normal University, Nanchong 637000, China; 2.School of Environment and Life Science, Nanning Normal University, Nanning 530001, China; 3. Guangxi Key Laboratory of Arable Land Conservation, Agricultural Resources and Environmental Research Institute, Guangxi Academy of Agricultural Sciences, Nanning 530007, China)Abstract: We investigated the effects of UiO-66-SH on the growth and development of hydroponically grown Brassica chinensis under different concentrations of arsenic(As)and cadmium(Cd)stress. By measuring indicators such as the biomass of Pakchoi, the level of heavy metal enrichment, the content of malondialdehyde(MDA). and the activities of antioxidant enzymes, the adsorption mechanism of UiO-66-SH towards the combined pollution of arsenic and cadmium was analyzed.The results showed that the fresh and dry weights of both above-ground and below-ground parts of Brassica chinensis decreased with- 收稿日期:2024-09-05;修回日期:2024-11-18 基金项目:广西耕地保育重点实验室开放课题(23-026-12-24KF3);国家重点研发计划课题(2023YFD1902400-02) 第一作者:王焱(1999—),女,西华师范大学在读硕士研究生,主要从事土壤重金属研究.E-mail:threefire72@163.com 通信作者:张拓(1990—),男,南宁师范大学副教授,主要从事水环境化学方向研究. E-mail:xiaotuodujiang@126.com 第3期王焱等:砷镉胁迫下UiO-66-SH对水培小白菜生长发育的影响河北大学学报(自然科学版) 第45卷the increase of As and Cd concentrations, while the decreasing trend was significantly weakened by the addition of UiO-66-SH. In addition, the addition of UiO-66-SH also promoted the growth of Brassica chinensis root length, plant height and leaf spreading, especially in the low concentration of the treatment was more significant; in heavy metal enrichment, UiO-66-SH showed good adsorption performance on As and Cd in the water body, the adsorption rate of Cd reached 69.5% and 60.2% in the low and high concentration treatments, respectively, the adsorption rate of As reached 71.1% and 63.1%, this adsorption significantly reduced the absorption and enrichment of As and Cd in Brassica chinensis, thus reducing the toxic effects of heavy metals on Brassica chinensis; Furthermore, UiO-66-SH alleviated oxidative damage by reducing the content of MDA and the increases in the activities of superoxide dismutase(SOD), peroxidase(POD), catalase(CAT), and ascorbate peroxidase(APX). The results indicated that the synchronous adsorption process of UiO-66-SH on arsenic and cadmium is mainly through the action of Zr—O—H and S—H bonds, and through the way of ligand complexation, more stable Zr—O—As and S—Cd bonds are formed on the surface of the material, thus achieving synchronous removal. In summary, the present study demonstrated that UiO-66-SH has a significant effect in alleviating the inhibitory effects of As and Cd stress on the growth and development of Brassica chinensis, and it is a kind of environmentally functional material with promising applications in the future.
    Simulation of an improved fractional-order supercritical unit water-to-coal ratio control method
    LI Shizhe, DUYiheng, LIU Shuai
    2025, 45(3):  289-298.  DOI: 10.3969/j.issn.1000-1565.2025.03.007
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    To address the mismatch in response speeds between coal and water feed rates in supercritical units and parameter perturbations caused by operational condition variations, this study simplifies the fuel-intermediate point temperature control system into a single-input-single-output form with parametric uncertainties to determine parameter variation ranges. A fractional-order quantitative feedback control scheme is developed for this uncertain system, incorporating multiple performance metrics to optimize control effectiveness. An enhanced multi-objective particle swarm optimization algorithm is implemented to balance control performance optimization with iteration efficiency while improving parameter search accuracy. Simulation results demonstrate that the proposed fractional order quantitative feedback theory system significantly enhances the water-coal ratio regulation performance and ensures safe and stable unit operation.- DOI:10.3969/j.issn.1000-1565.2025.03.007基于改进的分数阶超临界机组水煤比控制方法仿真李士哲1,杜毅恒1,刘帅2(1.华北电力大学 自动化系,河北 保定 071003;2.华北电力大学 河北省发电过程仿真与优化控制技术创新中心,河北 保定 071003)摘 要:针对超临界机组给煤量与给水流量响应速度不匹配以及工况变动引发的参数摄动问题,提出将燃料-中间点温度控制系统简化为具有参数不确定性的单输入单输出形式,以便确定参数变动范围.设计了一种针对该参数不确定性系统的分数阶定量反馈控制方案,并引入多重性能指标以优化控制效果.采用改进的多目标粒子群算法来解决控制系统性能优化与迭代效率之间的平衡并提升参数寻优的准确性.仿真结果表明,所提出的分数阶定量反馈控制系统能够显著提升超临界机组水煤比系统的控制性能,保障机组安全稳定运行.关键词:超临界机组;水煤比控制系统;分数阶控制;定量反馈理论;多目标粒子群算法中图分类号:TP273 文献标志码:A 文章编号:1000-1565(2025)03-0289-10Simulation of an improved fractional-order supercritical unit water-to-coal ratio control methodLI Shizhe1, DUYiheng1, LIU Shuai2(1. Department of Automation, North China Electric Power University, Baoding 071003, China; 2. Hebei Technology Innovation Center of Simulation & Optimized Control for Power Generation, North China Electric Power University, Baoding 071003, China)Abstract: To address the mismatch in response speeds between coal and water feed rates in supercritical units and parameter perturbations caused by operational condition variations, this study simplifies the fuel-intermediate point temperature control system into a single-input-single-output form with parametric uncertainties to determine parameter variation ranges. A fractional-order quantitative feedback control scheme is developed for this uncertain system, incorporating multiple performance metrics to optimize control effectiveness. An enhanced multi-objective particle swarm optimization algorithm is implemented to balance control performance optimization with iteration efficiency while improving parameter search accuracy. Simulation results demonstrate that the proposed fractional order quantitative feedback theory system significantly enhances the water-coal ratio regulation performance and ensures safe and stable unit operation.- 收稿日期:2024-11-26;修回日期:2025-03-12 基金项目:国家自然科学基金资助项目(61973117);华北电力大学中央高校基本科研业务项目(9160323007);河北省省级科技计划项目(22567643H);深圳市可持续发展科技专项资助项目(KCXFZ20201221173402007 ) 第一作者:李士哲(1981—),男,华北电力大学副教授,博士,主要从事控制系统的性能评价及诊断、大数据可视化等方向研究. E-mail:lishizhe121@163.com 通信作者:杜毅恒(1998—),男,华北电力大学在读硕士研究生,主要从事分数阶控制方向研究.E-mail:294147137@qq.com 第3期李士哲等:基于改进的分数阶超临界机组水煤比控制方法仿真河北大学学报(自然科学版) 第45卷
    Research progress on artificial intelligence-assisted deep-sea vehicle exploration technology
    LIAO Yong, ZHU Junhao
    2025, 45(3):  299-308.  DOI: 10.3969/j.issn.1000-1565.2025.03.008
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    Served as a vital reservoir of resources for human, the ocean contains abundant water, mineral, and biological resources. However, the complexity and extremity of the deep-sea environment impose significant limitations on human exploration efforts. Consequently, developing deep-sea detection technologies, particularly artificial intelligence(AI)-assisted deep-sea vehicle exploration technologies, has become an urgent necessity for augmenting scientific knowledge and fostering sustainable resource utilization. Therefore, this paper systematically reviews the application of AI on several critical technologies of deep-sea vehicles, including underwater navigation and communication, underwater path planning and safe obstacle avoidance, underwater target detection and recognition, as well as fault diagnosis and fault-tolerant control mechanisms of underwater vehiches. Furthermore, it pinpoints the challenges and obstacles which AI-assisted deep-sea exploration are currently confronted with and analyzes prospective developmental trends for such technologies, thus providing a reference for future researches in this field.
    Remote sensing image object detection based on improved YOLOv8
    KE Qisheng, HUA Qiang, ZHANG Bo
    2025, 45(3):  309-316.  DOI: 10.3969/j.issn.1000-1565.2025.03.009
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    Despite the significant advancements in object detection technology, object detection in remote sensing images still faces numerous challenges. These challenges mainly arise from the inconspicuous nature of objects, complex backgrounds, a high proportion of small objects, and imbalanced object classes in remote sensing images, leading to insufficient detection accuracy.This article proposes a remote sensing image target detection algorithm(Remote Sensing-YOLOv8, RS-YOLOv8). The focus is on optimizing the bottleneck layer module, and by proposing a multi-scale feature self-attention fusion structure, the sensitivity and screening capabilities for small-scale targets and multi-level features are improved, and the missed detection rate is reduced. The EMASlideLoss optimization loss function is designed to enhance the processing capabilities of complex samples, and the DySample dynamic upsampling strategy is introduced to improve the upsampling quality, and to a certain extent, improve the increase in the number of model parameters caused by the new modules. Experiments on the SIMD data set show that RS-YOLOv8 significantly improves the missed detection of small targets, with mAP reaching 83.7%, 3.7% higher than YOLOv8, showing excellent detection performance and broad application prospects.- DOI:10.3969/j.issn.1000-1565.2025.03.009基于改进YOLOv8的遥感图像目标检测柯淇晟1,花强1,张博2( 1. 河北大学 数学与信息科学学院,河北 保定 071002;2. 河北农业大学 理学院,河北 保定 071001)摘 要:尽管目标检测技术已日趋成熟,但针对遥感图像的目标检测仍面临诸多挑战,主要源于遥感图像中目标特征不明显、背景复杂、小目标占比高以及目标类别不均衡等问题,导致检测精度不足.本文提出了一种遥感图像目标检测算法(Remote Sensing-YOLOv8,RS-YOLOv8),重点优化了瓶颈层模块,通过提出多尺度特征自注意融合结构提升了对小尺度目标和多层级特征的敏感度与筛选能力,降低了漏检率.设计EMASlideLoss优化损失函数,增强了对复杂样本的处理能力,并引入DySample动态上采样策略提升上采样质量,并在一定程度上改善了因新增模块导致的模型参数量增加.在SIMD数据集上的实验表明,RS-YOLOv8显著改善了小目标的漏检情况,mAP达到83.7%,较YOLOv8提升3.7%,展现出优异的检测性能和广泛的应用前景.关键词:目标检测;YOLOv8;注意力模块;遥感图像中图分类号:TP391.7 文献标志码:A 文章编号:1000-1565(2025)03-0309-08Remote sensing image object detection based on improved YOLOv8KE Qisheng1, HUA Qiang1, ZHANG Bo2(1. School of Mathematics and Information Science, Hebei University, Baoding 07101,China) 2. School of Science, Hebei Agricultural University, Baoding 071001, China)Abstract: Despite the significant advancements in object detection technology, object detection in remote sensing images still faces numerous challenges. These challenges mainly arise from the inconspicuous nature of objects, complex backgrounds, a high proportion of small objects, and imbalanced object classes in remote sensing images, leading to insufficient detection accuracy.This article proposes a remote sensing image target detection algorithm(Remote Sensing-YOLOv8, RS-YOLOv8). The focus is on optimizing the bottleneck layer module, and by proposing a multi-scale feature self-attention fusion structure, the sensitivity and screening capabilities for small-scale targets and multi-level features are improved, and the missed detection rate is reduced. The EMASlideLoss optimization loss function is designed to enhance the processing capabilities of complex samples, and the DySample dynamic upsampling strategy is introduced to improve the upsampling quality, and to a certain extent, improve the increase in the number of model parameters caused by the new modules. Experiments on the SIMD data set show that RS-YOLOv8 significantly improves the missed detection of small targets, with mAP reaching 83.7%, 3.7% higher than YOLOv8, showing excellent detection performance and broad application prospects.- 收稿日期:2024-10-15;修回日期:2024-11-20 基金项目:科技部重点研发计划项目(2022YFE0196100) 第一作者:柯淇晟(2000—),男,河北大学在读硕士研究生,主要从事机器学习、计算机视觉方面研究.E-mail:1223482107@qq.com 通信作者:花强(1973—),男,河北大学教授,主要从事机器学习、人工神经网络方面的研究.E-mail:huaq@hbu.edu.cn 第3期柯淇晟等:基于改进YOLOv8的遥感图像目标检测河北大学学报(自然科学版) 第45卷
    Hierarchical model-based imbalanced wind speed forecast correction
    CAO Yang, ZHAI Junhai, HAN Ling
    2025, 45(3):  317-326.  DOI: 10.3969/j.issn.1000-1565.2025.03.010
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    To address the data imbalance problem in wind speed forecast correction, a correction model based on a classification/regression hierarchical structure is proposed. The core idea of this model is to adopt a divide-and-conquer strategy to gradually address the data imbalance in wind speed data. In the classification layer, a reweighting strategy is used to preliminarily address the data imbalance. In the regression layer, a group-wise expansion training strategy is proposed to effectively correct samples incorrectly classified due to imbalance, further addressing the data imbalance issue. Additionally, a probability weighting method based on a greedy strategy is designed to provide more accurate predictions for confident samples. The corrected wind speed forecasts showed a 34.4% reduction in overall Mean Absolute Error, with a 69.0% reduction for extreme wind speed events, indicating that the model not only improves the prediction accuracy for extreme wind speed events but also maintains performance in predicting stable events.
    Vehicle re-identification based on cross-layer attention and multi-memory
    QI Yuliang, WANG Weiming, WANG Jing, XIONG Yanzhen, LI Hui
    2025, 45(3):  327-336.  DOI: 10.3969/j.issn.1000-1565.2025.03.011
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    In order to improve the discriminant performance of the feature representation in the vehicle re-identification task,most of the current methods enrich the discriminant information by extracting the global information and local information of the vehicle respectively through the multi-branch structure,this will not only increase the network parameters, but also consume a lot of time.In order to solve the above problems,a vehicle re-identification method based on cross-layer attention and multiple memory units is proposed. Firstly, a cross-layer attention module is proposed to extract shallow global texture information and deep local semantic information in a single branch network,and then the cross-layer attention mechanism is used to assign weights to fuse the information of different layers.Then, the instance memory and the class memory are constructed to store the instance and class features respectively,and the influence of noise samples on feature representation is reduced by identity loss based on multiple memory.The experimental results show that the mAP,CMC@1 and CMC@5 of the proposed method on VeRi-776 dataset increase by- DOI:10.3969/j.issn.1000-1565.2025.03.011基于跨层注意力与多记忆单元的车辆重识别方法齐玉亮1, 2,王伟明2,王静3,熊彦臻4,李慧4(1.河北大学 河北省机器视觉工程研究中心,河北 保定 071002;2.河北高速公路集团有限公司 京雄分公司,河北 高碑店 074004;3.河北省交通运输运行监测与信息服务中心,河北 石家庄 050031;4.河北大学 网络空间安全与计算机学院,河北 保定 071002)摘 要:为了提高车辆重识别任务中特征表示的判别性能,目前大部分方法通过多分支结构来分别提取车辆的全局信息和局部细节信息,这样不仅会增加网络参数,同时还会消耗大量的时间.为了解决上述问题,提出了一种基于跨层注意力与多记忆单元的车辆重识别方法.首先,提出一种跨层注意力模块提取单分支网络中浅层的局部空间信息和深层的全局语义信息,再通过跨层注意力机制分配权重来融合不同层的信息,构建实例记忆单元和类别记忆单元来分别储存实例级特征和类别级特征,并通过基于多记忆单元的身份损失来削弱噪声样本对特征表示的影响.实验结果表明,所提出方法在VeRi-776数据集上的mAP、CMC@1、CMC@5相比于基线网络分别提高了1.5%、0.3%、0.1%.在VehicleID数据集中测试集大小为800、1 600、2 400时CMC@1相比于基线网络分别提高了1.9%、2.8%、3.8%.关键词:跨层注意力;实例记忆单元;类别记忆单元;车辆重识别中图分类号:TP183 文献标志码:A 文章编号:1000-1565(2025)03-0327-10Vehicle re-identification based on cross-layer attention and multi-memoryQI Yuliang1,2, WANG Weiming2, WANG Jing3, XIONG Yanzhen4, LI Hui4(1. Hebei Machine Vision Engineering Research Center,Hebei University,Baoding 071002,China;2. China Hebei Expressway Group Co.,Ltd. Jingxiong Branch,Gaobeidian 074004,China;3. Hebei Provincial Transportation Operation Monitoring and Information Service Center, Shijiazhuang 050031, China; 4. School of Cyber Security and Computer, Hebei University, Baoding 071002, China)Abstract: In order to improve the discriminant performance of the feature representation in the vehicle re-identification task,most of the current methods enrich the discriminant information by extracting the global information and local information of the vehicle respectively through the multi-branch structure,this will not only increase the network parameters, but also consume a lot of time.In order to solve the above problems,a vehicle re-identification method based on cross-layer attention and multiple memory units is proposed. Firstly, a cross-layer attention module is proposed to extract shallow global texture information and deep local semantic information in a single branch network,and then the cross-layer attention mechanism is used to assign weights to fuse the information of different layers.Then, the instance memory and the class memory are constructed to store the instance and class features respectively,and the influence of noise samples on feature representation is reduced by identity loss based on multiple memory.The experimental results show that the mAP,CMC@1 and CMC@5 of the proposed method on VeRi-776 dataset increase by- 收稿日期:2024-12-31;修回日期:2025-02-27 基金项目:河北高速公路集团“智能车载一体机”科技创新项目(冀高创〔2023〕294号) 第一作者:齐玉亮(1979—),男,河北省机器视觉工程研究中心工程师,主要从事高速车辆识别方向研究.E-mail:108715625@qq.com 通信作者:李慧(1993—),女,河北大学助理实验师,主要从事机器视觉方向研究.E-mail:lihui15794@hbu.edu.cn 第3期齐玉亮等:基于跨层注意力与多记忆单元的车辆重识别方法河北大学学报(自然科学版) 第45卷1.5%,0.3% and 0.1%,respectively,compared with the baseline network.With test set sizes of 800,1 600 and 2 400 in the VehicleID dataset CMC@1 increases by 1.9%,2.8% and 3.8% over the baseline network,respectively.