脑蛋白水解物的应用、制备工艺及质量标准研究进展

doi:10.3969/j.issn.1000-1565.2025.04.006

摘要/Abstract

摘要： 脑蛋白水解物是猪脑经酶解、过滤后得到的多肽和氨基酸的混合物.脑蛋白水解物可对周围或中枢神经系统的神经元发挥神经营养活性作用,在辅助治疗多种神经退行性疾病方面具有较好效果.本文围绕脑蛋白水解物的应用、制备工艺和质量标准等方面进行了综述,为进一步改进脑蛋白水解物生产工艺和开发新型口服型产品提供了参考.

关键词: 脑蛋白水解物, 神经退行性疾病, 脱脂, 酶解

Abstract: Cerebroprotein hydrolysate is a mixture of polypeptides and amino acids obtained from porcine brain after enzymatic hydrolysis and filtration. Cerebroprotein hydrolysate can exert neurotrophic activity on neurons in the peripheral or central nervous system, and has a good effect in the adjuvant treatment of various neurodegenerative diseases. This review mainly introduced the application, preparation process and quality standards of cerebroprotein hydrolysate, which provided a reference for further improving the production process of cerebroprotein hydrolysate and developing new oral products.

Key words: cerebroprotein hydrolysate, neurodegenerative diseases, delipidation, enzymatic hydrolysis

中图分类号:

R971

谭之磊,耿雪,盛子晗,金星雨,许峰,李金红. 脑蛋白水解物的应用、制备工艺及质量标准研究进展[J]. 河北大学学报(自然科学版), 2025, 45(4): 378-388.

TAN Zhilei, GENG Xue, SHENG Zihan, JIN Xingyu, XU Feng, LI Jinhong. Research progress on application, preparation process and quality standard of cerebroprotein hydrolysates[J]. Journal of Hebei University(Natural Science Edition), 2025, 45(4): 378-388.

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