Abstract: According to the nature immunology, This paper describe a computer security model imitated the principle of nature immunity--GECISM (GEneral Computer Immune System Model). This model are structured by agents. The agent imitates the immune cells. Through rules and co-operation the agent discriminate "self" and "non_self". Further it eliminates "non-self".

Key words: computer immune, multi-agent, imitate-nature, network security