Preparation technology of Artemisia argyi formula granules

doi:10.3969/j.issn.1000-1565.2022.03.006

Abstract

Abstract: In order to reduce the loss of volatile was oil in the preparation of standard decoction and formula granules, the volatile oil was included with β-cyclodextrin(β-CD), and the inclusion rate of volatile oil was used as an evaluation index to optimize the package of volatile oil and β-CD. Gas chromatography was used to determine the inclusion rate. The correlation among decoction pieces, standard decoction and formula granules was investigated by the content determination of index components and fingerprint. The average inclusion rate of volatile oil obtained by inclusion process was 96.40%, and the preparation method of Artemisia argyi standard decoction and formula granules was established. The average content of eucalyptus olein in the formula granules was 0.738 4 mg/g, and the transfer rate was 33.48%. The average content of borneol was 0.334 1 mg/g, and the transfer rate was 25.41%. The inclusion process and the preparation process of formula granules have high stability and good repeatability.The content of index components of standard decoction and formula granules is consistent, which can provide theoretical reference for industrial production of enterprises.

Key words: chromatographic analysis, Artemisia argyi, eucalyptol, borneol, β-cyclodextrin

CLC Number:

R917

LIANG Siyi, JI Shengnan, TIAN Luxiao, ZHI Jingyi, LI Lili, HA Jing. Preparation technology of Artemisia argyi formula granules[J]. Journal of Hebei University(Natural Science Edition), 2022, 42(3): 256-264.

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