Journal of Hebei University(Natural Science Edition) ›› 2025, Vol. 45 ›› Issue (4): 378-388.DOI: 10.3969/j.issn.1000-1565.2025.04.006

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Research progress on application, preparation process and quality standard of cerebroprotein hydrolysates

TAN Zhilei1, GENG Xue1, SHENG Zihan1, JIN Xingyu1, XU Feng2, 3, LI Jinhong2, 3   

  1. 1. State Key Laboratory of Food Nutrition and Safety, College of Bioengineering, Tianjin University of Science and Technology, Tianjin 300457, China; 2. Hebei Zhitong Biopharmaceutical Co., Ltd., Baoding 072656, China; 3. Hebei Province Animal Derived Peptide Biochemical Drug Technology Innovation Center, Baoding 072656, China
  • Received:2024-10-17 Online:2025-07-25 Published:2025-07-11

Abstract: Cerebroprotein hydrolysate is a mixture of polypeptides and amino acids obtained from porcine brain after enzymatic hydrolysis and filtration. Cerebroprotein hydrolysate can exert neurotrophic activity on neurons in the peripheral or central nervous system, and has a good effect in the adjuvant treatment of various neurodegenerative diseases. This review mainly introduced the application, preparation process and quality standards of cerebroprotein hydrolysate, which provided a reference for further improving the production process of cerebroprotein hydrolysate and developing new oral products.

Key words: cerebroprotein hydrolysate, neurodegenerative diseases, delipidation, enzymatic hydrolysis

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