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25 July 2026, Volume 46 Issue 4

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Influence of scour site seismic waveforms on the time-course response of large-diameter variable-section single pile

FENG Zhongju, YU Mingwei, ZHANG Cong, JIN Xibin, WANG Xiqing, WANG Fuchun

2026, 46(4):  337-348.  DOI: 10.3969/j.issn.1000-1565.2026.04.001

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To investigate the time-history response of large-diameter variable-section single pile subjected to different seismic waves in scouring sites, vibration table tests were conducted to examine the time-history characteristics of pore pressure ratio in the pile foundation soil layer, pile body acceleration, horizontal displacement at pile top, and bending moment in the pile body. Results indicate that as scour depth increases from 0 cm to 12 cm, the onset time of pore pressure ratio growth exhibits a pre-effect. Acceleration along the pile shaft shows a non-linear, increasing distribution from pile base to pile top, peaking at the pile top. The acceleration response of the pile-soil system is influenced by seismic waveform, soil type, and pile foundation stiffness. During the initial phase of seismic motion, pile-head horizontal displacement increased gradually. It surged sharply once accumulated vibrational energy exceeded the elastic confinement limit of the surrounding soil, subsequently stabilising as energy dissipated. Under- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.DOI:10.3969/j.issn.1000-1565.2026.04.001冲刷场地地震波形对大直径变截面单桩时程响应的影响冯忠居¹,于明威¹,张聪¹,金熙宾²,王溪清¹,王富春¹(1.长安大学 公路学院,陕西 西安 710064;2.中国铁路西安局集团有限公司 西安高铁基础设施段,陕西 西安 710054)摘 要:为探究冲刷场地在不同地震波作用下大直径变截面单桩的时程响应特性,通过振动台模型试验,研究了桩基础饱和砂土层孔压比、桩身加速度、桩顶水平位移及桩身弯矩的时程响应规律. 结果表明:随着冲刷深度由0 cm增加至12 cm,孔压比开始增长的时间表现出前置效应.桩身加速度沿纵向表现为由桩底向桩顶呈非线性递增分布,在桩顶处最大,桩-土体系的加速度响应受地震波形、土体类型及桩基刚度的影响. 地震动初期,桩顶水平位移增长缓慢,当振动能量累积至超出桩周土的弹性约束极限后急剧增大,之后随能量衰减逐渐趋于稳定. 在不同地震波作用下,各冲刷深度的桩身弯矩均随时间先增大后减小,并逐渐趋于稳定. 桩身弯矩峰值出现在饱和砂土层与强风化花岗岩层的交界面,变截面处的弯矩因截面刚度突变出现显著变化. 因此,大直径变截面单桩基础的抗震设计需重点强化土层分界面及变截面的抗弯性能. 关键词:桥梁工程;冲刷场地;振动台模型试验;单桩基础;时程响应中图分类号:U443.15 文献标志码:A 文章编号:1000-1565(2026)04-0337-12DOI:10.3969/j.issn.1000-1565.2026.04.001Influence of scour site seismic waveforms on the time-course response of large-diameter variable-section single pileFENG Zhongju¹, YU Mingwei¹, ZHANG Cong¹, JIN Xibin², WANG Xiqing¹, WANG Fuchun¹(1.School of Highway, Changan University, Xian 710064,China; 2.Xian High-Speed Rail Infrastructure Section,China Railway Xian Bureau Group Co., Ltd., Xian 710054,China)Abstract: To investigate the time-history response of large-diameter variable-section single pile subjected to different seismic waves in scouring sites, vibration table tests were conducted to examine the time-history characteristics of pore pressure ratio in the pile foundation soil layer, pile body acceleration, horizontal displacement at pile top, and bending moment in the pile body. Results indicate that as scour depth increases from 0 cm to 12 cm, the onset time of pore pressure ratio growth exhibits a pre-effect. Acceleration along the pile shaft shows a non-linear, increasing distribution from pile base to pile top, peaking at the pile top. The acceleration response of the pile-soil system is influenced by seismic waveform, soil type, and pile foundation stiffness. During the initial phase of seismic motion, pile-head horizontal displacement increased gradually. It surged sharply once accumulated vibrational energy exceeded the elastic confinement limit of the surrounding soil, subsequently stabilising as energy dissipated. Under- 收稿日期:2025-08-21;修回日期:2026-03-13 基金项目:国家自然科学基金项目(52378322);陕西省科学技术协会青年人才托举计划项目(20250461);福建省交通科技攻关项目(202105);中央高校基本科研业务费专项资金项目(300102215110) 第一作者:冯忠居(1965—),男,长安大学教授,博士生导师,主要从事公路岩土工程方向研究. E-mail:ysf@gl.chd.edu.cn 通信作者:张聪(1994—),男,长安大学讲师,博士,主要从事桥梁深基础工程方向研究. E-mail:chdzc@chd.edu.cn 第4期冯忠居等:冲刷场地地震波形对大直径变截面单桩时程响应的影响河北大学学报(自然科学版) 第46卷different seismic wave actions, pile-body bending moments at various scour depths initially increased, then decreased over time before stabilising. The peak bending moment occurs at the interface between saturated sand and strongly weathered granite. At variable cross-sections, bending moments exhibit significant variations due to abrupt changes in sectional stiffness. Consequently, seismic design for large-diameter variable-section single pile foundations must prioritise enhancing the flexural capacity at soil interface zones and variable cross-sections.

Coordination between micro-expansion and strength development of carbide slag concrete based on random forest model

ZHANG Ju, WANG Fenglin, YAN Changwang, WANG Shuqian, LI Yanhui

2026, 46(4):  349-358.  DOI: 10.3969/j.issn.1000-1565.2026.04.002

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To address the inconsistency where the incorporation of carbide slag microcapsules(CSM)coated with high-temperature wax into concrete results in increased expansion rate yet decreased strength, this study takes carbide slag concrete as the research object and use a random forest regression model with carbide slag content, curing temperature, curing humidity, and age as input features to simultaneously and accurately predict the compressive strength and restricted expansion rate of concrete. The optimized model achieves a coefficient of determination(R²)exceeding 0.99 for both synchronous predictions of compressive strength and restricted expansion rate, demonstrating high predictive reliability and effectiveness.- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:张菊,王凤林,闫长旺,等.基于随机森林模型的电石渣混凝土微膨胀与强度发展协调性研究［J］.河北大学学报(自然科学版),2026,46(4):349-358.DOI:10.3969/j.issn.1000-1565.2026.04.002基于随机森林模型的电石渣混凝土微膨胀与强度发展协调性研究张菊¹,王凤林¹,闫长旺²,王淑倩²,李彦辉³(1.内蒙古工业大学 土木工程学院,内蒙古 呼和浩特 010051;2.内蒙古工业大学 资源与环境工程学院,内蒙古 呼和浩特 010051;3. 呼伦贝尔市交通运输局综合保障中心,内蒙古 呼伦贝尔 021008)摘 要:针对高温蜡包裹的电石渣微胶囊(carbide slag microcapsules,CSM)掺入混凝土引起膨胀率上升而强度下降的不协调现象,以电石渣混凝土为研究对象,采用电石渣掺量、养护温度、养护湿度、龄期作为输入特征构建随机森林回归模型,对混凝土抗压强度与限制膨胀率进行同步精准预测. 优化后的模型对混凝土抗压强度与限制膨胀率的决定系数(R²)均超过0.99,具有较高的预测可靠性与有效性. 研究结果表明:混凝土强度与微膨胀的协调性受电石渣掺量、养护温度、养护湿度共同调控,中高电石渣掺量在养护中期协调效果显著,40 ℃养护条件协调性最优,60 ℃则因微胶囊失稳导致抗压强度损失加剧,自然养护条件严重抑制水化与膨胀反应,标准养护条件为最佳养护湿度条件.因此,可依据不同养护环境中的预测结果,通过控制电石渣掺量实现对混凝土强度与微膨胀性能的精准调控.关键词:随机森林模型;电石渣混凝土;限制膨胀率;抗压强度;协调性能中图分类号:TU528.55 文献标志码:A 文章编号:1000-1565(2026)04-0349-10DOI:10.3969/j.issn.1000-1565.2026.04.002Coordination between micro-expansion and strength development of carbide slag concrete based on random forest modelZHANG Ju¹, WANG Fenglin¹, YAN Changwang², WANG Shuqian², LI Yanhui³(1. School of Civil Engineering, Inner Mongolia University of Technology, Hohhot 010051, China;2. School of Resources and Environmental Engineering, Inner Mongolia University of Technology, Hohhot 010051, China;3. Comprehensive Support Center of Hulunbuir Transportation Bureau, Hulunbuir 021008, China)Abstract: To address the inconsistency where the incorporation of carbide slag microcapsules(CSM)coated with high-temperature wax into concrete results in increased expansion rate yet decreased strength, this study takes carbide slag concrete as the research object and use a random forest regression model with carbide slag content, curing temperature, curing humidity, and age as input features to simultaneously and accurately predict the compressive strength and restricted expansion rate of concrete. The optimized model achieves a coefficient of determination(R²)exceeding 0.99 for both synchronous predictions of compressive strength and restricted expansion rate, demonstrating high predictive reliability and effectiveness.- 收稿日期:2025-11-09;修回日期:2026-04-09 基金项目:国家自然科学基金项目(52368036);内蒙古科技计划项目(2025YFHH0016;2025YFHH0023);内蒙古自然科学基金项目(2025LHMS05008) 第一作者:张菊(1977—),女,内蒙古工业大学教授,主要从事固废资源化利用方向研究. E-mail: zj970741@126.com 第4期张菊等:基于随机森林模型的电石渣混凝土微膨胀与强度发展协调性研究河北大学学报(自然科学版) 第46卷The research findings indicate that the coordination between concrete strength and micro-expansion is jointly regulated by carbide slag content, curing temperature, and humidity. Medium to high carbide slag contents exhibit significant coordination effects in the middle curing stage, with the optimal coordination achieved under 40 ℃ curing conditions. At 60 ℃, the instability of microcapsules intensifies strength loss, while the natural curing environment severely inhibits hydration and expansion reactions, making standard curing the optimal humidity condition. Based on the above findings, precise regulation of concrete strength and micro-expansion performance can be realized by controlling the carbide slag content according to the prediction results under different curing environments.

Dynamic characteristics and simulation analysis of bolted joint of skew girder section of steel box girder bridge

YANG Sanqiang, LI Chengwang, LIU Qi, GAO Yisong, LIU Na

2026, 46(4):  359-366.  DOI: 10.3969/j.issn.1000-1565.2026.04.003

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The mechanical state of bolted joints in skewed girder sections of steel box girder bridges is complex, posing a key technical challenge in bridge design and construction. Based on the construction project of the prestressed concrete steel box girder bridge over the Beijing-Harbin expressway on the Qinhuangdao section of G102 national highway, simulation analysis and linear monitoring technologies were adopted to obtain the internal stress variation law of high-strength friction bolt groups in skewed girder sections. A mechanical model of high-strength friction bolt groups in skewed girder sections was established using ANSYS finite element software, and the deformation characteristics of skewed girder sections under different connection modes were analyzed, the optimal connection mode was obtained, and the dynamic characteristics of high-strength friction bolt groups were revealed. The dynamic load data show that the most unfavorable positions of the bolt group are the 5th and 15th columns. Under dynamic load, the maximum shear stress of the high-strength friction bolt group presents an approximately saddle-shaped- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:杨三强,李成旺,刘琦,等.钢箱梁桥斜交梁段栓接处动力学特性与仿真分析［J］.河北大学学报(自然科学版),2026,46(4):359-366.DOI:10.3969/j.issn.1000-1565.2026.04.003钢箱梁桥斜交梁段栓接处动力学特性与仿真分析杨三强,李成旺,刘琦,高毅松,刘娜(河北大学 建筑工程学院,河北省基础设施防灾减灾与智能评估重点实验室,河北 保定 071002)摘 要:钢箱梁桥斜交梁段栓接处受力状态复杂,是桥梁设计与施工面临的关键技术难题. 依托G102线秦皇岛上跨京哈高速公路预应力混凝土钢箱梁桥建设项目,采用仿真分析技术与线形监测技术,获取了斜交梁段高强度摩擦型螺栓群内应力变化规律;借助ANSYS有限元软件构建了斜交梁段高强度摩擦型螺栓群力学模型,分析了不同连接方式下的斜交梁段变形特征,得到了最优连接方式,揭示了高强度摩擦型螺栓群动力学特性. 动荷载数据显示,螺栓群不利受力位置为第5列、第15列;螺栓群在受到动荷载时,高强度摩擦型螺栓群剪应力最大值近似马鞍形分布,其主要特征是螺栓群两侧剪应力最大、中间剪应力最小、从螺栓群两侧向中间递减. 数值仿真分析结果表明,相同荷载条件下铆接的剪应力最大值约为高强度摩擦型螺栓连接的177%,焊接的应力最大值约为高强度摩擦型螺栓连接的440%,证实了栓接为最优连接方式.研究结果对钢箱梁桥螺栓群结构的设计、施工和监测具有重要的科学依据和工程参考.关键词:钢箱梁;连接方式;高强度摩擦型螺栓群;数值仿真;动力学特性中图分类号:U441 文献标志码:A 文章编号:1000-1565(2026)04-0359-08DOI:10.3969/j.issn.1000-1565.2026.04.003Dynamic characteristics and simulation analysis of bolted joint of skew girder section of steel box girder bridgeYANG Sanqiang, LI Chengwang, LIU Qi, GAO Yisong, LIU Na (Key Laboratory of Infrastructure Disaster Mitigation and Intelligent Assessment of Hebei Province, College of Civil Engineering and Architecture, Hebei University, Baoding 071002, China)Abstract:The mechanical state of bolted joints in skewed girder sections of steel box girder bridges is complex, posing a key technical challenge in bridge design and construction. Based on the construction project of the prestressed concrete steel box girder bridge over the Beijing-Harbin expressway on the Qinhuangdao section of G102 national highway, simulation analysis and linear monitoring technologies were adopted to obtain the internal stress variation law of high-strength friction bolt groups in skewed girder sections. A mechanical model of high-strength friction bolt groups in skewed girder sections was established using ANSYS finite element software, and the deformation characteristics of skewed girder sections under different connection modes were analyzed, the optimal connection mode was obtained, and the dynamic characteristics of high-strength friction bolt groups were revealed. The dynamic load data show that the most unfavorable positions of the bolt group are the 5th and 15th columns. Under dynamic load, the maximum shear stress of the high-strength friction bolt group presents an approximately saddle-shaped- 收稿日期:2025-02-21;修回日期:2026-04-09 基金项目:河北省高等学校科学技术研究项目(CXY2024012);河北省交通运输厅科技项目(202312;202305) 第一作者:杨三强(1980—),男,河北大学教授,博士生导师,主要从事桥梁监控、公路路基和路面材料方向研究.E-mail: ysq0999@163.com 第4期杨三强等:钢箱梁桥斜交梁段栓接处动力学特性与仿真分析河北大学学报(自然科学版) 第46卷distribution, which is mainly characterized by the maximum shear stress at both sides of the bolt group and the minimum shear stress in the middle, decreasing gradually from both sides to the middle of the bolt group. The numerical simulation results show that under the same load conditions, the maximum shear stress of riveted connections is about 177% of that of high-strength friction bolted connections, and the maximum stress of welded connections is about 440% of that of high-strength friction bolted connections, confirming that bolted connection is the optimal connection mode. The research results provide important scientific basis and engineering reference for the design, construction and monitoring of bolt group structures in steel box girder bridges.

Numerical simulation on spiral patterns in gas discharge system

YANG Fan, LIU Shuhua

2026, 46(4):  367-373.  DOI: 10.3969/j.issn.1000-1565.2026.04.004

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Dynamics of spiral patterns has been simulated using the Ginzburg-Landau equation. The influences of initial condition, boundary perturbation and boundary shape have been simulated. The simulation result shows that the initial condition and the parameters control the type of pattern; boundary condition incorporates the interplay between the environment and the system. When the symmetry of the boundary conditions is different from the symmetry of the force field, the system state is the result of the two different symmetries interacting. That is the boundary conditions modulate the pattern morphology to some extent. The smaller the area scale, the more obvious the boundary effect.The simulated results match the experiment results. This work is of importance for understanding and controlling spiral patterns.

Screening of proteins interacting with protein tyrosine kinase LYN

LONG Tongyun, YANG Yanlei, QI Mengnan, ZHANG Yanfen, LIU Zhongcheng

2026, 46(4):  374-382.  DOI: 10.3969/j.issn.1000-1565.2026.04.005

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To refine the signal transduction network mediated by the protein tyrosine kinase LYN and clarify its regulatory mechanism in allergic diseases, this study used a yeast two-hybrid system to screen target proteins that specifically interact with LYN. Self-activation activity and cytotoxicity of the bait protein were verified using haploid and diploid mating assays. Primary positive clones were subjected to sequencing alignment and bioinformatics analysis, and protein-protein interactions were further validated by yeast reversion experiments. A total of 53 potential interacting proteins were obtained in the primary screening. After removing invalid sequences including frameshift mutations, non-coding region translations, and coding region deletions, 10 candidate interacting proteins were retained. Combining bioinformatics analysis and yeast reversion experiments validation, the specific interaction between LYN and polyubiquitin-B precursor(UBB)was finally confirmed. This study provides an experimental basis for- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:龙通云,杨艳蕾,齐梦楠,等.蛋白酪氨酸激酶LYN互作蛋白筛选［J］.河北大学学报(自然科学版),2026,46(4):374-382.DOI:10.3969/j.issn.1000-1565.2026.04.005蛋白酪氨酸激酶LYN互作蛋白筛选龙通云,杨艳蕾,齐梦楠,张艳芬,刘中成(河北大学 药学院,河北省药物质量分析控制重点实验室,河北 保定 071002)摘 要:为完善蛋白酪氨酸激酶LYN介导的信号转导网络,明确其在变态反应性疾病中的调控机制,采用酵母双杂交系统筛选与LYN存在特异性相互作用的靶蛋白.通过单倍体与二倍体接合实验验证诱饵蛋白的自激活活性与细胞毒性,对初筛获得的阳性克隆进行测序比对和生物信息学分析,并通过酵母回转实验验证蛋白间互作关系.经初筛获得53个潜在互作蛋白,剔除移码突变、非编码区翻译及编码区翻译缺失等无效序列后,得到10个候选互作蛋白.结合生物信息学预测与回转实验验证,最终证实LYN与多聚泛素B前体(polyubiquitin-B precursor,UBB)存在特异性相互作用.本研究为深入阐明LYN在变态反应性疾病中的调控机制提供了实验依据,也为相关疾病治疗提供了新的潜在靶点.关键词:LYN;酵母文库;酵母双杂交;互作蛋白;生物信息学分析中图分类号:R593.1 文献标志码:A 文章编号:1000-1565(2026)04-0374-09DOI:10.3969/j.issn.1000-1565.2026.04.005Screening of proteins interacting with protein tyrosine kinase LYNLONG Tongyun, YANG Yanlei, QI Mengnan, ZHANG Yanfen, LIU Zhongcheng(Key Laboratory of Pharmaceutical Quality Control of Hebei Province, College of Pharmaceutical Sciences, Hebei University, Baoding 071002, China)Abstract: To refine the signal transduction network mediated by the protein tyrosine kinase LYN and clarify its regulatory mechanism in allergic diseases, this study used a yeast two-hybrid system to screen target proteins that specifically interact with LYN. Self-activation activity and cytotoxicity of the bait protein were verified using haploid and diploid mating assays. Primary positive clones were subjected to sequencing alignment and bioinformatics analysis, and protein-protein interactions were further validated by yeast reversion experiments. A total of 53 potential interacting proteins were obtained in the primary screening. After removing invalid sequences including frameshift mutations, non-coding region translations, and coding region deletions, 10 candidate interacting proteins were retained. Combining bioinformatics analysis and yeast reversion experiments validation, the specific interaction between LYN and polyubiquitin-B precursor(UBB)was finally confirmed. This study provides an experimental basis for- 收稿日期:2026-02-13;修回日期:2026-04-07 基金项目:河北省自然科学基金项目(H2022201035;H2023201026) 第一作者:龙通云(1999—), 女, 河北大学在读硕士研究生, 主要从事基因工程制药和分子药理学方向研究.E-mail:2742486460@qq.com 通信作者:刘中成(1979—), 男, 河北大学教授, 主要从事基因工程制药和分子药理学方向研究.E-mail:liuzc@hbu.edu.cn 第4期龙通云等:蛋白酪氨酸激酶LYN互作蛋白筛选河北大学学报(自然科学版) 第46卷further elucidating the regulatory mechanism of LYN in allergic diseases and offers novel potential targets for the treatment of related disorders.

Effect of baicalin on the inflammatory pathway of macrophages in LM infection

ZHANG Enhua, ZHANG Zonghao, CHEN Jing, ZHAO Ziang, WEI Xi, GAO Zheng, LI Wenyan

2026, 46(4):  383-393.  DOI: 10.3969/j.issn.1000-1565.2026.04.006

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To investigate changes in the gene expression profile and identify key inflammatory genes and signaling pathways involved in baicalin(BA)intervention against Listeria monocytogenes(LM)infection in murine macrophages, cells were divided into three groups:Control, LM-infected(LM), and BA-treated plus LM-infected(LM+BA). Following treatment, transcriptome sequencing(RNA-seq)was performed. Differentially expressed genes(DEGs)were screened and subjected to protein-protein interaction(PPI)analysis, Gene Ontology(GO)enrichment, and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis. Key findings were validated using reverse transcription-quantitative polymerase chain reaction(RT-qPCR). The results revealed 744 DEGs by comparing the LM group vs. the control group and the LM+BA group vs. the LM group. PPI analysis identified 82 core DEGs. These DEGs were primarily enriched in six inflammatory signaling pathways. RT-qPCR validation confirmed that the mRNA expression trends were consistent with the RNA-seq data. Therefore, we established BAs regulatory targets within LM-triggered inflammatory pathways, advancing our understanding of its anti-inflammatory properties and proposing new avenues for listeriosis control.- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:张恩华,张宗昊,陈静,等.黄芩苷对LM感染的巨噬细胞炎性通路的影响［J］.河北大学学报(自然科学版),2026,46(4):383-393.DOI:10.3969/j.issn.1000-1565.2026.04.006黄芩苷对LM感染的巨噬细胞炎性通路的影响张恩华^1,2,张宗昊¹,陈静¹,赵子昂¹,魏熙¹,高政¹,李文艳¹(1.河北大学 基础医学院,河北 保定 071000;2. 河北大学 生命科学学院,河北 保定 071002)摘 要:为探究黄芩苷(baicalin,BA)干预单核细胞增生李斯特菌(Listeria monocytogenes, LM)感染小鼠巨噬细胞后基因表达谱的变化及其涉及的炎症关键基因和信号通路,将巨噬细胞分为3组:对照组、LM组和LM+BA组.对细胞处理后进行转录组测序,筛选出差异表达基因进行蛋白质互作、GO和KEGG分析,并通过RT-qPCR验证.结果显示:交叉分析LM组和对照组、LM+BA组和LM组,获得744个差异表达基因.蛋白质互作分析获得82个核心差异基因,主要富集的炎性通路6条.RT-qPCR结果表明mRNA表达趋势与测序结果相一致.因此,本研究筛选出了BA可能干预的LM引起炎症的相关信号通路和差异表达基因,为BA的抗炎机制和李斯特菌病的防治提供新思路.关键词:单核细胞增生李斯特菌;黄芩苷;转录组;RAW264.7细胞;炎性通路中图分类号:R392.12 文献标志码:A 文章编号:1000-1565(2026)04-0383-11DOI:10.3969/j.issn.1000-1565.2026.04.006Effect of baicalin on the inflammatory pathway of macrophages in LM infectionZHANG Enhua^1,2, ZHANG Zonghao¹, CHEN Jing¹, ZHAO Ziang¹, WEI Xi¹, GAO Zheng¹, LI Wenyan¹(1. Basic Medical College, Hebei University, Baoding 071000,China;2. College of Life Sciences, Hebei University, Baoding 071002, China)Abstract: To investigate changes in the gene expression profile and identify key inflammatory genes and signaling pathways involved in baicalin(BA)intervention against Listeria monocytogenes(LM)infection in murine macrophages, cells were divided into three groups:Control, LM-infected(LM), and BA-treated plus LM-infected(LM+BA). Following treatment, transcriptome sequencing(RNA-seq)was performed. Differentially expressed genes(DEGs)were screened and subjected to protein-protein interaction(PPI)analysis, Gene Ontology(GO)enrichment, and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis. Key findings were validated using reverse transcription-quantitative polymerase chain reaction(RT-qPCR). The results revealed 744 DEGs by comparing the LM group vs. the control group and the LM+BA group vs. the LM group. PPI analysis identified 82 core DEGs. These DEGs were primarily enriched in six inflammatory signaling pathways. RT-qPCR validation confirmed that the mRNA expression trends were consistent with the RNA-seq data. Therefore, we established BAs regulatory targets within LM-triggered inflammatory pathways, advancing our understanding of its anti-inflammatory properties and proposing new avenues for listeriosis control.- 收稿日期:2025-06-26;修回日期:2025-09-27 基金项目:河北大学创新训练计划项目(S202510075134;DC2026560);河北大学实验室开放项目(sy202567);河北省中医药管理局项目(2023136) 第一作者:张恩华(1998—),女,河北大学在读博士研究生,主要从事分子生物学研究.E-mail:ly2580233@163.com 通信作者:李文艳(1973—),女,河北大学副教授,博士,主要从事生殖生物学研究.E-mail:liwenyan358@163.com 第4期张恩华等:黄芩苷对LM感染的巨噬细胞炎性通路的影响河北大学学报(自然科学版) 第46卷

Bacteriostatic activity and mechanism of carvacrol against Elizabethkingia miricola

LI Yi, WU Sixuan, CHEN Lifei, LU Chongyang, LI Wei

2026, 46(4):  394-402.  DOI: 10.3969/j.issn.1000-1565.2026.04.007

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Elizabethkingia miricola is the pathogen responsible for frog head tilt disease, posing a serious threat to frog aquaculture. Carvacrol has potential applications as a feed additive in aquaculture due to its broad-spectrum antibacterial properties. To evaluate the efficacy of carvacrol in the prevention and treatment of E. miricola infections, we assessed its antibacterial activity against E. miricola and further explored its mechanisms of action. The results revealed that the minimum inhibitory concentration(MIC)and minimum bactericidal concentration(MBC)of carvacrol against E. miricola were 100 μg/mL and 200 μg/mL, respectively. After treatment with carvacrol, the concentration of soluble proteins decreased significantly, while the DNA extravasation increased. Carvacrol treatment resulted in cell deformation, shrinkage, and membrane rupture, as well as a reduction in biofilm formation with a significant down-regulation- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:李义,吴司璇,陈丽菲,等.香芹酚对米尔伊丽莎白菌的抑菌活性及机制研究［J］.河北大学学报(自然科学版),2026,46(4):394-402.DOI:10.3969/j.issn.1000-1565.2026.04.007香芹酚对米尔伊丽莎白菌的抑菌活性及机制研究李义,吴司璇,陈丽菲,鲁重阳,李伟(长江大学 生命科学学院,湖北 荆州 434025)摘 要:米尔伊丽莎白菌(Elizabethkingia miricola)是蛙类“歪头病”的致病病原,对蛙类的健康养殖构成严重威胁.香芹酚具有广谱抗菌的特性,在水产养殖中有作为饲料添加剂的潜在可能.为评估香芹酚应用于防治米尔伊丽莎白菌感染的潜力,测定了其对米尔伊丽莎白菌的抑菌能力,并探究了其作用机制.结果表明:香芹酚对米尔伊丽莎白菌的最小抑菌浓度(minimun inhibitory concentration,MIC)和最小杀菌浓度(minimun bactericidal concentration,MBC)分别为100 μg/mL和200 μg/mL.经香芹酚处理后,细菌菌体可溶性蛋白浓度显著降低,DNA外渗量增加;香芹酚处理导致菌体变形、细胞膜皱缩及破裂,生物膜形成大幅降低,并且生物膜合成相关基因的表达被显著下调.上述结果表明:香芹酚对米尔伊丽莎白菌具有较好的抑菌活性,其通过影响细菌蛋白质的正常合成,破坏细胞膜的完整性以及减少生物膜的形成来抑制细菌的生长.这为香芹酚作为抗菌剂应用于防控蛙类米尔伊丽莎白菌感染提供了参考.关键词:米尔伊丽莎白菌;香芹酚;作用机制;抑菌作用;抗菌剂中图分类号:Q939.9 文献标志码:A 文章编号:1000-1565(2026)04-0394-09DOI:10.3969/j.issn.1000-1565.2026.04.007Bacteriostatic activity and mechanism of carvacrol against Elizabethkingia miricolaLI Yi, WU Sixuan, CHEN Lifei, LU Chongyang, LI Wei(College of Life Science, Yangtze University, Jingzhou 434025,China)Abstract: Elizabethkingia miricola is the pathogen responsible for frog head tilt disease, posing a serious threat to frog aquaculture. Carvacrol has potential applications as a feed additive in aquaculture due to its broad-spectrum antibacterial properties. To evaluate the efficacy of carvacrol in the prevention and treatment of E. miricola infections, we assessed its antibacterial activity against E. miricola and further explored its mechanisms of action. The results revealed that the minimum inhibitory concentration(MIC)and minimum bactericidal concentration(MBC)of carvacrol against E. miricola were 100 μg/mL and 200 μg/mL, respectively. After treatment with carvacrol, the concentration of soluble proteins decreased significantly, while the DNA extravasation increased. Carvacrol treatment resulted in cell deformation, shrinkage, and membrane rupture, as well as a reduction in biofilm formation with a significant down-regulation- 收稿日期:2025-09-16;修回日期:2025-10-21 基金项目:广西作物病虫害生物学重点实验室开放课题(22-035-31-23KF01);国家级大学生创新创业训练项目(202410489016) 第一作者:李义(2000—),男,长江大学在读硕士研究生,主要从事生物防治方向研究.E-mail:2014332889@qq.com 通信作者:李伟(1976—),男,长江大学副教授,博士,主要从事病原微生物学方向研究.E-mail:wetli@yangtzeu.edu.cn 第4期李义等:香芹酚对米尔伊丽莎白菌的抑菌活性及机制研究河北大学学报(自然科学版) 第46卷of genes related to biofilm synthesis. These findings suggest that carvacrol exhibits strong inhibitory activity against E. miricola by disrupting bacterial protein synthesis, compromising cell membrane integrity, and reducing biofilm formation. This study provides valuable data supporting the use of carvacrol as an antibacterial agent for preventing and controlling frog diseases caused by E. miricola infection.

Secondary metabolites of fungus Fusarium sp. J3 and their bioactivity

SU Yaning, LIU Huiying, TANG Hongliang, WANG Runyan, ZHAO Xiaolong, LUO Duqiang

2026, 46(4):  403-412.  DOI: 10.3969/j.issn.1000-1565.2026.04.008

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In this study, the secondary metabolites of fungus Fusarium sp. J3 were isolated and identified to explore novel compounds that possess unique structures and biological activities. The ethyl acetate extract of the rice fermentation of the fungus was purified by separation technologies such as silica gel column chromatography, gel column chromatography and high-performance liquid chromatography(HPLC), and the chemical structures of these compounds were elucidated by NMR and ESI-MS. A total of 17 compounds were isolated, including 1 aromatic compound(14), 1 amide compound(15), 3 terpenoids(16, 22, 28), 3 cyclic peptides(17, 29, 30), 1 ketene compound(18), 5 esters(19, 20, 23, 24, 25), and 3 steroids(21, 26, 27). Among these compounds, 24 was isolated from genus Fusarium for the first time. The anti-inflammatory and anti-tumor activities of these compounds were evaluated. Compounds 17, 24 and 30 showed certain anti-inflammatory effect at a mass concentration of 10 μg/mL, with the inhibition rates against NO reaching about 45%. Compound 29 displayed significant inhibitory activity- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:苏亚宁,刘惠颖,唐宏亮,等.镰刀菌属真菌Fusarium sp.J3次级代谢产物及生物活性［J］.河北大学学报(自然科学版),2026,46(4):403-412.DOI:10.3969/j.issn.1000-1565.2026.04.008镰刀菌属真菌Fusarium sp.J3次级代谢产物及生物活性苏亚宁¹,刘惠颖¹,唐宏亮²,王润妍¹,赵晓珑¹,罗都强²(1.河北大学 化学与材料科学学院,河北 保定 071002;2.河北大学 生命科学学院,河北 保定 071002)摘 要:以镰刀菌Fusarium sp.J3为研究对象,挖掘结构新颖且具有生物活性的次级代谢产物.对真菌Fusarium sp.J3进行大米发酵,通过硅胶柱层析、凝胶柱层析、高效液相色谱(HPLC)等分离技术分离发酵物的乙酸乙酯提取物,利用NMR、ESI-MS等波谱解析技术进行化合物结构鉴定.从目标菌株的乙酸乙酯提取物中共分离得到了17个化合物,包含1个芳香类化合物(14),1个酰胺类化合物(15),3个萜类化合物(16,22,28),3个环肽类化合物(17,29,30),1个烯酮类化合物(18),5个酯类化合物(19,20,23,24,25)和3个甾体类化合物(21,26,27);其中,化合物24系新化合物,且首次从镰刀菌属真菌中分离得到.对所得化合物进行了抗炎和抗肿瘤活性测定,结果表明:化合物17、24和30在质量浓度为10 μg/mL时,具有一定的抗炎活性,对NO抑制率达到45%以上;化合物29对肿瘤细胞MCF-7具有显著抑制活性,IC₅₀值为6.77 μg/mL.关键词:Fusarium sp.J3;次级代谢产物;抗炎;抗肿瘤中图分类号:Q936 文献标志码:A 文章编号:1000-1565(2026)04-0403-10DOI:10.3969/j.issn.1000-1565.2026.04.008Secondary metabolites of fungus Fusarium sp. J3 and their bioactivitySU Yaning¹, LIU Huiying¹, TANG Hongliang², WANG Runyan¹, ZHAO Xiaolong¹, LUO Duqiang²(1. College of Chemistry and Materials Science, Hebei University, Baoding 071002, China; 2. College of Life Sciences, Hebei University, Baoding 071002, China)Abstract: In this study, the secondary metabolites of fungus Fusarium sp. J3 were isolated and identified to explore novel compounds that possess unique structures and biological activities. The ethyl acetate extract of the rice fermentation of the fungus was purified by separation technologies such as silica gel column chromatography, gel column chromatography and high-performance liquid chromatography(HPLC), and the chemical structures of these compounds were elucidated by NMR and ESI-MS. A total of 17 compounds were isolated, including 1 aromatic compound(14), 1 amide compound(15), 3 terpenoids(16, 22, 28), 3 cyclic peptides(17, 29, 30), 1 ketene compound(18), 5 esters(19, 20, 23, 24, 25), and 3 steroids(21, 26, 27). Among these compounds, 24 was isolated from genus Fusarium for the first time. The anti-inflammatory and anti-tumor activities of these compounds were evaluated. Compounds 17, 24 and 30 showed certain anti-inflammatory effect at a mass concentration of 10 μg/mL, with the inhibition rates against NO reaching about 45%. Compound 29 displayed significant inhibitory activity- 收稿日期:2025-08-28;修回日期:2026-03-26 基金项目:河北省生物医药联合基金项目(B2020201090);省级大学生创新训练计划项目(DC2025311) 第一作者:苏亚宁(2002—),女,河北大学在读硕士研究生,主要从事天然药物化学研究.E-mail:3176926395@qq.com 通信作者:赵晓珑(1980—),女,河北大学副教授,博士,主要从事金属配合物抗癌作用和天然产物化学研究.E-mail: longlong_666@sina.com罗都强(1968—),男,河北大学教授,博士,主要从事天然产物化学研究.E-mail:duqiangluo999@126.com 第4期苏亚宁等:镰刀菌属真菌Fusarium sp.J3次级代谢产物及生物活性河北大学学报(自然科学版) 第46卷toward MCF-7 cells with IC₅₀ value of 6.77 μg/mL.

Algorithm for imbalanced data classification based on dynamic boundary oversampling and improved KNN

HU Guikai, DAI Zhihan

2026, 46(4):  413-423.  DOI: 10.3969/j.issn.1000-1565.2026.04.009

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Imbalanced data classification is a critical challenge in machine learning. To address the performance limitations of traditional K-nearest neighbors and its variants in such tasks, this paper proposes a two-stage classification model that integrates dynamic boundary oversampling(DBO), ensemble learning, and an improved KNN method. The proposed approach first employs a DBO strategy at the data level to adaptively generate minority class samples, constructing multiple balanced subsets. Then, at the algorithm level, a double weighted class credibility K-nearest neighbors base classifier- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:胡桂开,代祉含.基于动态边界过采样与改进KNN的不平衡数据分类算法［J］.河北大学学报(自然科学版),2026,46(4):413-423.DOI:10.3969/j.issn.1000-1565.2026.04.009基于动态边界过采样与改进KNN的不平衡数据分类算法胡桂开¹,代祉含²(1.东华理工大学 理学院,江西 南昌 330013;2.东华理工大学 数字经济与资源管理学院,江西 南昌 330013)摘 要:不平衡数据分类是机器学习中的一项关键挑战.针对传统K近邻(K-nearest neighbors, KNN)及其变体在此任务中性能不佳的问题,本文提出了一种融合动态边界过采样、集成学习与改进K近邻的两阶段分类模型.首先,在数据层面采用动态边界过采样策略(dynamic boundary oversampling, DBO),自适应地生成少数类样本以构建多个平衡子集;其次,在算法层面为每个子集构建一个双重加权类可信度K近邻(double weighted class credibility K-nearest neighbors algorithm, DWCCKNN)基分类器,通过加权机制修正近邻计数并强化边界判别;然后,通过集成学习机制聚合预测结果以提升模型的准确性;最后,利用多个公开数据集将本文方法与经典过采样方法进行对比分析.结果表明:相对SMOTE-CCKNN、ADASYN-CCKNN及Borderline-SMOTE-CCKNN等方法,本文所提方法协同数据、算法与模型3层技术,有效提升了不平衡数据的分类性能.关键词:不平衡数据;KNN;过采样;集成学习中图分类号:TP181 文献标志码:A 文章编号:1000-1565(2026)04-0413-11DOI:10.3969/j.issn.1000-1565.2026.04.009Algorithm for imbalanced data classification based on dynamic boundary oversampling and improved KNNHU Guikai¹, DAI Zhihan²(1. School of Science, East China University of Technology, Nanchang 330013,China;2.School of Digital Economics and Resource Management, East China University of Technology, Nanchang 330013, China)Abstract: Imbalanced data classification is a critical challenge in machine learning. To address the performance limitations of traditional K-nearest neighbors and its variants in such tasks, this paper proposes a two-stage classification model that integrates dynamic boundary oversampling(DBO), ensemble learning, and an improved KNN method. The proposed approach first employs a DBO strategy at the data level to adaptively generate minority class samples, constructing multiple balanced subsets. Then, at the algorithm level, a double weighted class credibility K-nearest neighbors base classifier- 收稿日期:2025-12-08;修回日期:2026-03-24 基金项目:国家自然科学基金项目(11661003;12561069);江西省自然科学基金项目(20192BAB201006) 第一作者:胡桂开(1977—),男,东华理工大学教授,博士,主要从事回归模型统计推断、机器学习及其应用方向研究.E-mail:huguikai97@163.com 第4期胡桂开等:基于动态边界过采样与改进KNN的不平衡数据分类算法河北大学学报(自然科学版) 第46卷is built for each subset,which employs a weighting mechanism to rectify the neighbor-counting bias and enhance boundary discrimination.Subsequently, an ensemble learning mechanism aggregates the prediction results to improve the model's accuracy. Finally, comparative experiments are conducted on multiple public datasets to evaluate the proposed method against classic oversampling approaches. The results demonstrate that, compared to methods such as SMOTE-CCKNN, ADASYN-CCKNN, and Borderline-SMOTE-CCKNN, the proposed approach effectively enhances the classification performance for imbalanced data by synergistically combining techniques at the data, algorithm, and model levels.

Path planning algorithm of mobile robot based on improved Informed RRT^*

ZHANG Zhenli, XIE Fei, YUAN Dakai, HAN Shuren

2026, 46(4):  424-436.  DOI: 10.3969/j.issn.1000-1565.2026.04.010

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To address the issues of strong sampling randomness, low efficiency in random tree expansion, and poor path smoothness in the traditional Informed RRT^* algorithm for path planning, an improved Informed RRT^* algorithm is proposed. The algorithm adopts a hybrid sampling strategy that combines Gaussian-biased sampling with uniform random sampling to reduce sampling randomness and improve the efficiency of initial path discovery. Bayesian learning is introduced to adaptively adjust the sampling weights and the Gaussian standard deviation. During node expansion, an improved artificial potential field and a greedy step-size expansion strategy are incorporated to enhance the directionality of random tree growth and increase expansion efficiency. In the path post-processing stage, a dual-scale sliding- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:张振利,谢飞,袁达凯,等.基于改进Informed RRT^*的移动机器人路径规划算法［J］.河北大学学报(自然科学版),2026,46(4):424-436.DOI:10.3969/j.issn.1000-1565.2026.04.010基于改进Informed RRT^*的移动机器人路径规划算法张振利^1,2,谢飞^1,2,袁达凯^1,2,韩树人^1,2(1.江西理工大学 电气工程与自动化学院,江西 赣州 341000;2.江西理工大学 多维智能感知与控制江西省重点实验室,江西 赣州 341000)摘 要:针对传统的Informed RRT^*算法在路径规划中存在采样随机性强、随机树扩展效率低和路径不平滑等问题,提出一种改进Informed RRT^*算法.该算法采用高斯偏置与均匀随机相结合的混合采样策略来降低采样随机性和提高初始路径搜索效率,并利用贝叶斯学习自适应调整采样权重与高斯标准差;在节点扩展阶段融合改进的人工势场与贪婪步长扩展策略,以增强随机树扩展的目的性并提高扩展速度;在路径后处理中,采用双尺度滑动窗口裁剪与欧拉螺线-圆弧-欧拉螺线(Clothoid-Arc-Clothoid, CAC)曲线平滑方法,以减少冗余节点并提高路径平滑性.通过仿真实验对比表明,改进Informed RRT^*算法获取初始路径时间更短,算法收敛效率更高,所得路径的长度更短且更平滑.关键词:Informed RRT^*; 路径规划; 高斯偏置; 人工势场; CAC曲线中图分类号:TP242.2 文献标志码:A 文章编号:1000-1565(2026)04-0424-13DOI:10.3969/j.issn.1000-1565.2026.04.010Path planning algorithm of mobile robot based on improved Informed RRT^*ZHANG Zhenli^1,2, XIE Fei^1,2, YUAN Dakai^1,2, HAN Shuren^1,2(1.School of Electrical Engineering and Automation, Jiangxi University of Science and Technology, Ganzhou 341000, China; 2.Jiangxi Provincial Key Laboratory of Multidimensional Intelligent Perception and Control, Jiangxi University of Science and Technology, Ganzhou 341000, China)Abstract: To address the issues of strong sampling randomness, low efficiency in random tree expansion, and poor path smoothness in the traditional Informed RRT^* algorithm for path planning, an improved Informed RRT^* algorithm is proposed. The algorithm adopts a hybrid sampling strategy that combines Gaussian-biased sampling with uniform random sampling to reduce sampling randomness and improve the efficiency of initial path discovery. Bayesian learning is introduced to adaptively adjust the sampling weights and the Gaussian standard deviation. During node expansion, an improved artificial potential field and a greedy step-size expansion strategy are incorporated to enhance the directionality of random tree growth and increase expansion efficiency. In the path post-processing stage, a dual-scale sliding- 收稿日期:2025-12-01;修回日期:2026-04-07 基金项目:国家自然科学基金项目(62363013);多维智能感知与控制江西省重点实验室项目(2024SSY03161) 第一作者:张振利(1976—),男,江西理工大学副教授,主要从事人工智能、检测技术与控制方向研究.E-mail:47717770@qq.com 通信作者:韩树人(1983—),女,江西理工大学讲师,主要从事网络化测控和物联网技术方向研究.E-mail:18911107@qq.com 第4期张振利等:基于改进Informed RRT^*的移动机器人路径规划算法河北大学学报(自然科学版) 第46卷window pruning method and a Clothoid-Arc-Clothoid(CAC)curve smoothing technique are employed to remove redundant nodes and improve path smoothness. Simulation results demonstrate that the improved Informed RRT^* algorithm achieves shorter initial path search time, higher convergence efficiency, and generates shorter and smoother paths.

Dual-branch dynamic feature enhancement network for SAR image denoising

LIU Ming, ZHOU Yonglu, ZHAO Yuhang, LIU Shuaiqi, ZHAO Shuhuan

2026, 46(4):  437-448.  DOI: 10.3969/j.issn.1000-1565.2026.04.011

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Aiming at the problem that the existing denoising algorithms often ignore the low contrast region of the image, we propose a dual-branch network for speckle noise suppression, namely, the dual-branch- 引用格式:冯忠居,于明威,张聪,等.冲刷场地地震波形对大直径变截面单桩时程响应的影响［J］.河北大学学报(自然科学版),2026,46(4):337-348.引用格式:刘明,周永露,赵宇航,等.基于双分支动态特征增强的SAR图像去噪［J］.河北大学学报(自然科学版),2026,46(4):437-448.DOI:10.3969/j.issn.1000-1565.2026.04.011基于双分支动态特征增强的SAR图像去噪刘明^1,2,周永露^1,3,赵宇航^1,3,刘帅奇^1,3,赵淑欢^1,3(1.河北大学 电子信息工程学院,河北 保定 071002;2.河北大学 信息技术中心,河北 保定 071002;3.河北省机器视觉技术创新中心,河北 保定 071002)摘 要:针对现有去噪算法常常忽视图像低对比度区域的问题,本文提出一种用于散斑噪声抑制的双分支网络——双分支动态特征增强网络(dual-branch dynamic feature enhancement network,DDFE-Net).DDFE-Net包含2个基于U形网络的分支,分别是低对比度区域特征增强(feature enhancement in low contrast areas,FELCA)分支和小波域特征增强(wavelet domain feature enhancement,WDFE)分支.FELCA分支首先通过动态特征提取(dynamic feature extraction,DFE)模块对图像的互补特征进行提取,并采用动态多头Transformer(dynamic multi-head attention Transformer,DMFormer)捕获全局特征,从而增强了低对比度区域的特征.WDFE分支首先利用残差模块对含噪声的输入图像进行底层特征编码,再通过动态小波域关联器(dynamic wavelet domain correlator,DWDC)模块建立图像小波不同频率之间的对应关系,进一步增加图像的空间连续性.最终,DDFE-Net将2个分支所获得的特征进行融合,重建出高质量去噪图像.实验结果表明:DDFE-Net在噪声抑制、边缘保护和计算效率方面均优于现有方法,尤其在处理复杂噪声时表现出更强的鲁棒性.关键词:SAR图像去噪;深度学习;动态特征提取;动态小波域关联器中图分类号:TN95 文献标志码:A 文章编号:1000-1565(2026)04-0437-12DOI:10.3969/j.issn.1000-1565.2026.04.011Dual-branch dynamic feature enhancement network for SAR image denoisingLIU Ming^1,2, ZHOU Yonglu^1,3, ZHAO Yuhang^1,3, LIU Shuaiqi^1,3, ZHAO Shuhuan^1,3(1. College of Electronic and Informational Engineering, Hebei University, Baoding 071002, China;2. Information Technology Center, Hebei University, Baoding 071002, China;3. Machine Vision Technology Innovation Center of Hebei Province, Baoding 071002, China)Abstract: Aiming at the problem that the existing denoising algorithms often ignore the low contrast region of the image, we propose a dual-branch network for speckle noise suppression, namely, the dual-branch- 收稿日期:2025-08-28;修回日期:2026-01-13 基金项目:国家自然科学基金项目(62172139);中央引导地方科技发展基金项目(246Z0104G);河北省高等学校科学技术研究项目(BJ2026066) 第一作者:刘明(1985—),女,河北大学实验师,主要从事算法优化、多维信号处理、图像处理方向研究. E-mail:mliu_hbu@163.com 通信作者:赵淑欢(1987—),女,河北大学讲师,主要从事图像处理和信号处理方向研究. E-mail:zsh_hbu@163.com 第4期刘明等:基于双分支动态特征增强的SAR图像去噪河北大学学报(自然科学版) 第46卷dynamic feature enhancement network(DDFE-Net). DDFE-Net contains two branches based on U-shaped network, namely feature enhancement in low contrast areas(FELCA)branch and wavelet domain feature enhancement(WDFE)branch. The FELCA branch first extracts the complementary features of the image through the dynamic feature extraction(DFE)module, and uses the dynamic multi-head attention Transformer(DMFormer)to capture the global features, to enhance the features of the low contrast region. The WDFE branch first uses the residual module to encode the underlying features of the noisy input image, and then establishes the corresponding relationship between image frequencies in wavelet domain through the dynamic wavelet domain correlator(DWDC)to further increase the spatial continuity of the image. Finally, DDFE-Net fuse the features obtained from the two branches, and then reconstructed a high-quality denoised image. Experimental results show that DDFE-Net is superior to existing methods in noise suppression, edge protection and computational efficiency, especially in dealing with complex noise.