河北大学学报(自然科学版) ›› 2002, Vol. 22 ›› Issue (1): 77-79.DOI: 10.3969/j.issn.1000-1565.2002.01.020

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超声辐射下氢氧化钾催化的Michel加成

李记太,崔勇,程朝立,李同双   

  1. 河北大学化学与环境科学学院,河北,保定,071002
  • 出版日期:2002-02-25 发布日期:2002-02-25
  • 基金资助:
    河北省自然科学基金

Michael Addition Catalyzed by Potassium Hydroxide under Ultrasound Irradiation

  • Online:2002-02-25 Published:2002-02-25

摘要: 超声辐射下,查耳酮与含有活泼亚甲基的化合物诸如硝基甲烷、丙二酸二乙酯和乙酰乙酸乙酯等,在氢氧化钾催化下进行Michael加成,产品收率为75%~98%.该法具有反应时间短,产率高的优点.

关键词: 超声波, 查耳酮, Michel加成

Abstract: Michael addition of chalcone with active methylene compound such as diethyl malonate, ni tromethane and ethyl acetoacetate catalyzed by potassium hydroxide in anhydrous ethanol afforded the corre sponding Michael adducts in 75 %6~98 % yield under ultrasound.

Key words: Ultrasound, Chalcone, Michael addition

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