Application of 7-hydroxylcoumarin-aldehyde in the detection of hypochlorite

doi:10.3969/j.issn.1000-1565.2018.01.005

Abstract

Abstract: 7-hydroxylcoumarin-aldehyde can be used to detect hypochlorite in PBS(pH=7.4)solution.The results of spectra show that the probe has a fluorescence enhancement property for hypochlorite recognition in PBS(pH=7.4)solution, and the color of the solution changes from light yellow to deep-yellow, and the fluorescence of the solution changes from weak fluorescence to deep-blue fluorescence.The recognition response of the probe to hypochlorite can be rapidly completed within 1s, and the detection limit is found to be as low as 51.75 nmol/L.In addition, the probe can be used for fluorescence imaging of hypochlorite in HepG2 cells.

Key words: 7-hydroxylcoumarin-aldehyde, hypochlorite, fluorescence enhancement, fluorescence imaging

CLC Number:

O622.4

YIN Caixia, XIONG Kangming, HUO Fangjun. Application of 7-hydroxylcoumarin-aldehyde in the detection of hypochlorite[J]. Journal of Hebei University (Natural Science Edition), 2018, 38(1): 28-32.

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