毛细管电泳-联吡啶钌电化学发光测定利多卡因

doi:10.3969/j.issn.1000-1565.2010.06.009

摘要/Abstract

摘要： 基于利多卡因对联吡啶钌在铂电极上的电致发光信号有增敏作用,建立了一种测定利多卡因的毛细管电泳-电化学发光分析方法.讨论了磷酸盐缓冲液pH值、浓度、分离电压、检测电位等实验参数对利多卡因分离检测的影响.在优化的实验条件下,利多卡因在1.5～740 μmol/L内呈良好线性,检出限为0.1 μmol/L.应用此法测定了尿液中利多卡因的含量,回收率为 90%～93.5%.

中图分类号:

O657.3

孙汉文,问海芳,苏明. 毛细管电泳-联吡啶钌电化学发光测定利多卡因[J]. 河北大学学报(自然科学版), 2010, 30(6): 652-656.

SUN Han-wen,WEN Hai-fang,SU Ming. A Capillary Electrophoresis Method for the Analysis of Lidocaine by Electrochemiluminescence with Tris (2,2′-bipyridyl) ruthenium (Ⅱ)[J]. Journal of Hebei University (Natural Science Edition), 2010, 30(6): 652-656.

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