微波促进下3,4-二氢嘧啶-2-酮衍生物的有效合成及其抗菌活性

doi:10.3969/j.issn.1000-1565.2009.05.011

摘要/Abstract

摘要： 利用微波促进的方法,通过Biginelli反应,以脂肪醛和杂环醛为原料、三氟醋酸(或冰醋酸)为催化剂,简便、高效地合成了一系列含脂肪烃基或杂环基的3,4-二氢嘧啶-2-酮衍生物,并首次对化合物抗植物病菌活性进行了初步测试.

关键词: 3, 4-二氢嘧啶-2-酮, 微波促进有机合成, Biginelli反应

中图分类号:

O621.3

李小六,冯俊娜,王东跃,陈华,万素英,曹克强. 微波促进下3,4-二氢嘧啶-2-酮衍生物的有效合成及其抗菌活性[J]. 河北大学学报(自然科学版), 2009, 29(5): 489-494.

LI Xiao-liu,FENG Jun-na,WANG Dong-yue,CHEN Hua,WAN Su-ying,CAO Ke-qiang. Microwave Assisted Synthesis and Biological Study of 3,4-Dihydropyrimidin-2 (1H)-ones[J]. Journal of Hebei University (Natural Science Edition), 2009, 29(5): 489-494.

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