Abstract: Based on Lactococcus lactis metabolic pathway, the standardized reaction rate equations of the metabolites could be created automatically, and system model was builded. At the situation of assuming parameters, the varied curves of metabolites concentration was computed, the metabolic process of Lactococcus lactis was quantified. The results showed that 1)when the enzyme concentration was enough, the different initial value of glucose didn't influence the time that reaction reached balance and the occurrence of the extremum; 2)the revised model could apply to mutative strain, then could provide guidance of selecting strain , the complicacy and blindness of experiments can be reduced.

Key words: Lactococcus lactis, equation automation, system model