Loading...

Table of Content

    25 September 2023, Volume 43 Issue 5
    Upper bounds on the double Roman domination number in graphs
    HAO Guoliang,ZHUANG Wei,XIE Zhihong,ZENG Shuting
    2023, 43(5):  449-452.  DOI: 10.3969/j.issn.1000-1565.2023.05.001
    Asbtract ( 234 )   PDF (334KB) ( 166 )  
    References | Related Articles | Metrics
    By analyzing the structure of a graph and using the graph parameters, such as the number of vertices, diameter, minimum degree and packing number, some new upper bounds of the double Roman domination number of a connected graph are obtained.
    Profit distribution of water saving management contract in the fixed investment and return model based on Stackelberg game
    WANG Xiaosheng,NIU Shuyue
    2023, 43(5):  453-462.  DOI: 10.3969/j.issn.1000-1565.2023.05.002
    Asbtract ( 167 )   PDF (527KB) ( 80 )  
    References | Related Articles | Metrics
    Water saving management contract(WSMC)is a kind of water saving investment model by which water costs saved in the future is used to pay for the cost of project renovation and shared with participants. In order to reasonally address the profit distribution problem of WSMC in the fixed investment and return model, this paper takes initial investment amount, contract period and excess water saving income distribution ratio as research objectives, based on Stackebergs master-slave game theory, four profit distribution models under the non-cooperative game between the water users and the water saving service companies are established; and through numerical examples the optimal equilibrium strategies of the four profit distribution models are analyzed. The results show that the water saving service company and the water users respectively achieve the maximum profit value in the case of the Stackelberg equilibrium when they are in the dominant position. For this water saving renovation project, the economic benefit of the project achieves the maximum profit value when the water saving service company is the leader and the initial investment amount is in a priority decision; at the same time, choosing a water saving service company with higher water saving capacity can produce higher water saving benefits.- DOI:10.3969/j.issn.1000-1565.2023.05.002基于Stackelberg博弈的固定投资回报型合同节水管理收益分配王小胜1,牛淑月2(1. 河北工程大学 数理科学与工程学院,河北 邯郸 056038;2.河北工程大学 管理工程与商学院,河北 邯郸 056038)摘 要:合同节水管理(water saving management contract,WSMC)是用节约的水费支付项目改造成本并分享节水收益的一种节水投资模式.为了解决固定投资回报型模式下WSMC的收益分配问题,以初始投资额、合同期以及超额节水收益分配比例为研究对象,基于Stackelberg主从博弈理论,建立了用水户和节水服务公司在非合作博弈下的4种收益分配模型,并通过数值算例对4种模式下的最优策略进行分析.结果表明:节水服务公司和用水户分别在其处于主导地位时的Stackelberg均衡下取得最大利润,对于该节水改造项目而言,在节水服务公司主导且优先决策初始投资额的情况下,项目经济效益较好,同时选择较高节水能力的节水服务公司可以产生更高的节水收益.关键词:合同节水管理;固定投资回报型;收益分配;Stackelberg博弈中图分类号:TV213.4 文献标志码:A 文章编号:1000-1565(2023)05-0453-10Profit distribution of water saving management contract in the fixed investment and return model based on Stackelberg gameWANG Xiaosheng1,NIU Shuyue2(1. School of Mathematics and Physics, Hebei University of Engineering, Handan 056038, China; 2. School of Management Engineering and Business, Hebei University of Engineering, Handan 056038, China)Abstract: Water saving management contract(WSMC)is a kind of water saving investment model by which water costs saved in the future is used to pay for the cost of project renovation and shared with participants. In order to reasonally address the profit distribution problem of WSMC in the fixed investment and return model, this paper takes initial investment amount, contract period and excess water saving income distribution ratio as research objectives, based on Stackebergs master-slave game theory, four profit distribution models under the non-cooperative game between the water users and the water saving service companies are established; and through numerical examples the optimal equilibrium strategies of the four profit distribution models are analyzed. The results show that the water saving service company and the water users respectively achieve the maximum profit value in the case of the Stackelberg equilibrium when they are in the dominant position. For this water saving renovation project, the economic benefit of the project achieves the maximum profit value when the water saving service company is the leader and the initial investment amount is in a priority decision; at the same time, choosing a water saving service company with higher water saving capacity can produce higher water saving benefits.- 收稿日期:2022-08-16 基金项目:国家自然科学基金资助项目(61873084) 第一作者:王小胜(1969—),男,河北邯郸人,河北工程大学教授,博士,主要从事不确定统计预测与决策建模方向研究.E-mail:xswang@hebeu.edu.cn第5期王小胜等:基于Stackelberg博弈的固定投资回报型合同节水管理收益分配
    Effect of Ga3+ on the luminescence property of Mg14Ge5O24:Cr near infrared material
    XU Yanmei,QIN Xiaodong,LIANG Shaolong,WANG Jiarui,WANG Xuejiao,WANG Zhijun
    2023, 43(5):  463-469.  DOI: 10.3969/j.issn.1000-1565.2023.05.003
    Asbtract ( 214 )   PDF (1356KB) ( 135 )  
    References | Related Articles | Metrics
    Mg14Ge5O24:Cr near-infrared(NIR)phosphors were synthesized by the high-temperature solid-phase method to achieve the coexistence of Cr3+ and Cr4+ valence luminescence. The crystalline phases of the samples were analyzed using XRD and GASA refinement software. The material has two luminescence centers, one from Cr3+ occupying the octahedral Ge4+ position with an emission band in the NIR I region and a half-peak width up to 256 nm, and the other from Cr4+ occupying the tetrahedral Ge4+ position with an emission band in the NIR II region and a half-peak width up to 266 nm. The luminescence properties of the material were analyzed by low-temperature spectra and lifetime decay curves. The modulation of Cr3+ and Cr4+ luminescence can be achieved by using Ga3+ instead of Ge4+. The addition of large radius Ga3+ ions generates new lattice sites, which affects the overall crystal field intensity, and a phosphor with more intense luminescence in the NIR I region is obtained.
    Charge of dielectric particle deep into the plasma sheath in DC discharge
    CAI Zhimin,ZHANG Ning,ZHANG Shunxin,WANG Shuo,LIU Fucheng,HE Yafeng
    2023, 43(5):  470-475.  DOI: 10.3969/j.issn.1000-1565.2023.05.004
    Asbtract ( 165 )   PDF (905KB) ( 125 )  
    References | Related Articles | Metrics
    Aiming to understand the complex motion process of large dielectric particle in the DC discharge dusty plasma experiments, the electrical properties and charge of dielectric particle deep into the plasma sheath are studied by the theoretical analysis and numerical simulation. Results show that the electricity and the charge of large particle deep into the plasma sheath are completely different from that of the small particle suspended near the sheath boundary which were widely studied previously. When the distance between the particle and the electrode is less than 8.2 mm, the particle is positively charged. By modifying the calculation of ion charging current, the charge of particle with the radius of 250 μm is calculated to be about 5.2×106 e under the applied voltage of -280 V. This verifies previous experimental measurement results.
    Preparation and characterization of glutamate iron chelate
    LIU Xinshuo,WANG Zhen,LI Qing,YANG Wenzhi,LI Haiying
    2023, 43(5):  476-483.  DOI: 10.3969/j.issn.1000-1565.2023.05.005
    Asbtract ( 264 )   PDF (1302KB) ( 101 )  
    References | Related Articles | Metrics
    Glutamic acid(Glu)was reacted with trivalent iron ions(Fe3+)to prepare glutamate iron chelate [Glu-Fe(Ⅲ)]. Glu-Fe(Ⅲ)was characterized by FT-IR, DSC, and TGA analysis. The Fe3+ content in Glu-Fe(Ⅲ)was determined by an indirect iodometric method and identified as an evaluation index for optimizing the preparation condition of Glu-Fe(Ⅲ). The effects of molar ratio of glutamic acid to iron, pH, time and temperature on the iron content of Glu-Fe(Ⅲ)were investigated by single factor method and Box-Benhnken design(BBD). The optimum preparation condition of Glu-Fe(Ⅲ)was Glu/Fe3+ molar ratio of 3∶5, pH 4.8, 50 ℃ and 3 h, and the iron content of Glu-Fe(Ⅲ)prepared under the optimized conditions was 19.91%. Glu-Fe(Ⅲ)could be a new iron and glutamic acid nutrient supplement.
    Evaluation of uncertainty of measurement in determination of aflatoxin B1 content in polygala tenuifolia willd by HPLC
    MA Lihui,CUI Yan,LI Xun,ZHAO Zhilei
    2023, 43(5):  484-491.  DOI: 10.3969/j.issn.1000-1565.2023.05.006
    Asbtract ( 190 )   PDF (500KB) ( 88 )  
    References | Related Articles | Metrics
    In order to evaluate the uncertainty of measurement in the determination of aflatoxin B1 in polygala tenuifolia willd by high performance liquid chromatography(HPLC),according to the national metrology technical specifications described in JJF1059.1—2012 “Evaluation and Expression of Uncertainty in Measurement”, six samples were randomly selected, and the mathematical model was established to analyze uncertainty sources,quantify the uncertainty components, calculate synthetic uncertainty and extend uncertainty in terms of the dilution of standard solution, the weighing of the samples, the final volume of the samples and the repeatability of instrumental measurement. The experimental results showed that the combined uncertainty of aflatoxin B1 determination in polygala7 tenuifolia- DOI:10.3969/j.issn.1000-1565.2023.05.006HPLC法测定远志中黄曲霉毒素B1含量的不确定度评定马力辉1,2,3,崔炎1,2,3,李迅1,2,3,赵志磊1,2,3,4(1.河北大学 质量技术监督学院,河北 保定 071002;2.计量仪器与系统国家地方联合工程研究中心,河北 保定 071002;3.河北省能源计量与安全检测技术重点实验室,河北 保定 071002;4.河北大学 地理标志研究院,河北 保定 071002 )摘 要:为评定高效液相色谱法测定远志中黄曲霉毒素B1含量的不确定度,依据国家计量技术规范 JJF 1059.1—2012《测量不确定度评定与表示》,对随机选取的6 个远志样品,建立数学模型,从标准溶液稀释、样品称量、样品最终定容体积和仪器测定重复性等方面分析不确定度来源,量化不确定度分量,计算合成不确定度和扩展不确定度.实验结果表明远志中黄曲霉毒素B1测定结果合成标准不确定度为0.016 39 μg/kg,扩展不确定度0.032 78 μg/kg.不确定度评定结果表明:HPLC法对远志中黄曲霉毒素B1含量的测定数据可靠,远志中黄曲霉毒素B1含量的测量不确定度主要来源于重复性实验、标准曲线的拟合、液相色谱仪的使用.关键词:不确定度;黄曲霉毒素B1;HPLC;远志 中图分类号:O657.72 文献标志码:A 文章编号:1000-1565(2023)05-0484-08Evaluation of uncertainty of measurement in determination of aflatoxin B1 content in polygala tenuifolia willd by HPLCMA Lihui1,2,3,CUI Yan1,2,3,LI Xun1,2,3,ZHAO Zhilei1,2,3,4(1.College of Quality and Technical Supervision, Hebei University, Baoding 071002, China;2. National&Local Joint Engineering Research Center of Metrology Instrument and System, Baoding 071002, China;3. Hebei Key Laboratory of Energy Metering and Safety Testing Technology, Baoding 071002, China;4.Institute of Geographical Indications,Hebei University, Baoding 071002, China)Abstract: In order to evaluate the uncertainty of measurement in the determination of aflatoxin B1 in polygala tenuifolia willd by high performance liquid chromatography(HPLC),according to the national metrology technical specifications described in JJF1059.1—2012 “Evaluation and Expression of Uncertainty in Measurement”, six samples were randomly selected, and the mathematical model was established to analyze uncertainty sources,quantify the uncertainty components, calculate synthetic uncertainty and extend uncertainty in terms of the dilution of standard solution, the weighing of the samples, the final volume of the samples and the repeatability of instrumental measurement. The experimental results showed that the combined uncertainty of aflatoxin B1 determination in polygala7 tenuifolia- 收稿日期:2022-10-17 基金项目:河北省重点研发计划项目(21344801D) 第一作者:马力辉(1967—),男,河北定州人,河北大学教授,博士,主要从事检测技术及产品创新研究.E-mail:malihui@aliyun.com 通信作者:赵志磊(1977—),男,河北辛集人,河北大学教授,博士,主要从事食品药品质量检测技术.E-mail:15930721279@163.com第5期马力辉等:HPLC法测定远志中黄曲霉毒素B1含量的不确定度评定willd was 0.016 39 μg/kg and the extended uncertainty was 0.032 78 μg/kg.The uncertainty assessment results showed that determination of aflatoxin B1 in polygala tenuifolia willd by HPLC method were reliable, and the uncertainties of measurement in the determination of aflatoxin B1 in polygala tenuifolia willd were mainly come from the repeatability, the fitting of the standard curve, and the use of HPLC.
    Effect of NiO photocathode film thickness on the performance of quantum dot sensitized solar cells
    WANG Senyang,ZHANG Zhaoyou,SUN Jie,LIANG Chengyang,CAO Ying,GENG Shitong,LI Ling
    2023, 43(5):  492-499.  DOI: 10.3969/j.issn.1000-1565.2023.05.007
    Asbtract ( 156 )   PDF (1207KB) ( 86 )  
    References | Related Articles | Metrics
    This work is to explore the best preparation conditions of photoanode film materials in quantum dot sensitized solar cells(QDSSCs). P-type NiO nanoparticles are synthetized by one-step high temperature hydrothermal method, which is then screen printed on conductive glass to form NiO films. NiO films can be used as photocathode for quantum dot sensitized solar cells. Combine with Cu2S counter electrode, solar cells are assembled. NiO photocathode films with different film thicknesses were studied and tested repeatedly. The results show that the highest photoelectric conversion efficiency is achieved when the film thickness of NiO film material is 21 μm.
    Effects of ALDH2 gene knockout on the development of male mice
    XU Wenxiu,LIU Qingling,LIU Xiaohan,KONG Lingying,SHI Hui,ZHAO Zhenjun
    2023, 43(5):  500-505.  DOI: 10.3969/j.issn.1000-1565.2023.05.008
    Asbtract ( 194 )   PDF (1130KB) ( 146 )  
    References | Related Articles | Metrics
    In order to study the effects of ALDH2 gene knockout on the development of male mice, the effects of ALDH2 gene knockout on male mice were studied by analyzing the organ mass fraction of liver, kidney and testis, histomorphology, tissue antioxidant capacity and total litter size of mice at different weeks of age. The results showed that the cords of hepatocytes of Knockout type(KO)mice at 7 and 10 weeks of age were disordered. At 10 weeks of age, the number of multinucleated hepatocytes, and the black deposits in hepatocytes increased significantly. The kidneys of KO mice at 7 and 10 weeks of age showed obvious interstitial edema. In 7 and 10 weeks of aged mice, the sequence of late spermatogenic cells and spermatogenic cells in testicular seminiferous tubules were disordered. The total antioxidant capacity of liver and kidney in 10 weeks of age KO mice and the total antioxidant capacity of testis in 3 and 5 weeks of age KO mice were significantly lower than that of wild-type(WT)mice. The total number of pups in KO group was significantly less than that of WT mice. In conclusion, ALDH2 knockout can reduce the ability of anti-oxidative damage in liver, kidney and testis tissue of mice, result in cell damage, and affect the fertility of male mice in turn.The results showed that ALDH2 gene knockout would cause- DOI:10.3969/j.issn.1000-1565.2023.05.008乙醛脱氢酶ALDH2基因敲除对雄性小鼠发育的影响徐文秀,刘庆玲,刘笑含,孔令英,石慧,赵振军(烟台大学 生命科学学院,山东 烟台 264003)摘 要:为了研究乙醛脱氢酶ALDH2基因敲除对雄性小鼠发育的影响,将不同周龄ALDH2基因敲除的雄性小鼠,通过分析其肝、肾、睾丸脏器质量分数,组织细胞形态,组织抗氧化能力,总产仔数等指标,探讨ALDH2基因敲除对雄性小鼠的影响.结果表明:7、10周龄敲除型(KO)小鼠肝细胞索排列紊乱,10周龄时,多核肝细胞数量明显增多,且肝细胞中黑色沉积物增加;7、10周龄KO小鼠肾脏出现明显的间质水肿;7、10周龄KO小鼠睾丸生精管内晚期精细胞和精子排序紊乱,腔内有脱落的生精细胞,睾丸组织出现纤维化;10周龄KO小鼠肝脏、肾脏总抗氧化能力和3、5周龄KO小鼠睾丸组织总抗氧化能力显著低于野生型(WT)小鼠;KO组小鼠产仔总数显著少于WT小鼠.综上,ALDH2敲除导致小鼠肝脏、肾脏和睾丸组织抗氧化损伤的能力降低,造成其细胞氧化损伤,进而影响雄性小鼠的生育力.该研究结果说明ALDH2基因敲除会引发雄性小鼠组织器官发育异常,进而影响小鼠的个体发育.关键词:乙醛脱氢酶2;肝脏;肾脏;睾丸;组织抗氧化;生育力中图分类号:Q954.6 文献标志码:A 文章编号:1000-1565(2023)05-0500-06Effects of ALDH2 gene knockout on the development of male miceXU Wenxiu,LIU Qingling,LIU Xiaohan,KONG Lingying,SHI Hui,ZHAO Zhenjun(School of Life Sciences,Yantai University,Yantai 264003,China)Abstract: In order to study the effects of ALDH2 gene knockout on the development of male mice, the effects of ALDH2 gene knockout on male mice were studied by analyzing the organ mass fraction of liver, kidney and testis, histomorphology, tissue antioxidant capacity and total litter size of mice at different weeks of age. The results showed that the cords of hepatocytes of Knockout type(KO)mice at 7 and 10 weeks of age were disordered. At 10 weeks of age, the number of multinucleated hepatocytes, and the black deposits in hepatocytes increased significantly. The kidneys of KO mice at 7 and 10 weeks of age showed obvious interstitial edema. In 7 and 10 weeks of aged mice, the sequence of late spermatogenic cells and spermatogenic cells in testicular seminiferous tubules were disordered. The total antioxidant capacity of liver and kidney in 10 weeks of age KO mice and the total antioxidant capacity of testis in 3 and 5 weeks of age KO mice were significantly lower than that of wild-type(WT)mice. The total number of pups in KO group was significantly less than that of WT mice. In conclusion, ALDH2 knockout can reduce the ability of anti-oxidative damage in liver, kidney and testis tissue of mice, result in cell damage, and affect the fertility of male mice in turn.The results showed that ALDH2 gene knockout would cause- 收稿日期:2022-10-20 基金项目:国家重点研发计划(2018YFC1003600) 第一作者:徐文秀(1996—),女,山东临沂人,烟台大学在读硕士研究生,主要从事雄性小鼠生殖发育研究.E-mail:xwx5935@163.com 通信作者:赵振军(1976—),男,山东烟台人,烟台大学副教授,博士,主要从事小鼠生殖发育研究. E-mail:zhaozhenjun@ytu.edu.cn第5期徐文秀等:乙醛脱氢酶ALDH2基因敲除对雄性小鼠发育的影响abnormal development of tissues and organs in male mice, and then affect the individual development of mice.
    In vivo and in vitro anti-tumor and immunomodulation effect of compound Taisui oral liquid
    SHI Bingye,XIA Zihan,WANG Bei,JIN Wenxun
    2023, 43(5):  506-511.  DOI: 10.3969/j.issn.1000-1565.2023.05.009
    Asbtract ( 240 )   PDF (699KB) ( 83 )  
    References | Related Articles | Metrics
    To investigate the anti-tumor and immune function of compound Taisui oral liquid,(CTOL)in vivo and in vitro, the cytotoxic effects of different doses of CTOL on SGC7901 cells and Hela cells were detected in vitro. The inhibitory effect of CTOL in different concentrations on tumor cells proliferation was detected by MTT assay. S180 tumor-bearing mice were divided into six groups randomly, which are, model group, CTX group, low-dose of CTOL group, high-dose of CTOL group, low-dose of CTOL + CTX group and high-dose of CTOL + CTX group. CTX was intraperitoneally injected and different doses of CTOL were given by gavages. After 6 weeks of continuous administration,- DOI:10.3969/j.issn.1000-1565.2023.05.009复方太岁口服液体内外抗肿瘤及免疫调节作用 石炳烨1,2,夏子涵2,王蓓2,靳文勋3(1.河北大学附属医院 超声诊断科,河北 保定 071000;2.河北大学 基础医学院,河北 保定 071000;3.保定脑血管病医院 神经外科,河北 保定 071000)摘 要:为探讨复方太岁口服液(compound Taisui oral liquid, CTOL)体内外抗肿瘤及对免疫功能的调节作用,体外采用MTT法检测不同浓度CTOL对SGC7901和Hela 细胞增殖的抑制作用,体内制备S180 荷瘤小鼠模型,实验分为模型组、CTX组、CTOL低剂量组、CTOL高剂量组、CTOL低剂量+CTX组、CTOL高剂量+CTX组.CTX采用腹腔注射给药,CTOL采用灌胃方式给药,连续给药6周后处死小鼠,称取瘤质量和脾质量,计算抑瘤率和脾指数,ELISA法检测血清IL-2和IFN-γ水平.结果显示:不同浓度CTOL对SGC7901和Hela细胞均有抑制作用,且呈剂量依赖关系.体内各实验组瘤质量均明显低于模型组(P<0.05),其中CTOL高剂量+CTX组的抑瘤率最高为70.90%;CTOL低、高剂量+CTX组的脾指数、IL-2、IFN-γ水平均明显高于CTX组(P<0.05).由此可得:CTOL在体内外均可抑制肿瘤的生长,并可改善CTX导致的脾脏损伤及促进IL-2和IFN-γ的分泌.关键词:复方太岁口服液;抗肿瘤;免疫功能中图分类号:R285.5 文献标志码:A 文章编号:1000-1565(2023)05-0506-06In vivo and in vitro anti-tumor and immunomodulation effect of compound Taisui oral liquid SHI Bingye1,2,XIA Zihan2,WANG Bei2,JIN Wenxun3(1. Department of Ultrasound Diagnosis,Affiliated Hospital of Hebei University,Baoding 071000,China;2. School of Basic Medical Sciences,Hebei University, Baoding 071000,China; 3. Department of Neurosurgery,Baoding Cerebrovascular Disease Hospital,Baoding 071000,China)Abstract: To investigate the anti-tumor and immune function of compound Taisui oral liquid,(CTOL)in vivo and in vitro, the cytotoxic effects of different doses of CTOL on SGC7901 cells and Hela cells were detected in vitro. The inhibitory effect of CTOL in different concentrations on tumor cells proliferation was detected by MTT assay. S180 tumor-bearing mice were divided into six groups randomly, which are, model group, CTX group, low-dose of CTOL group, high-dose of CTOL group, low-dose of CTOL + CTX group and high-dose of CTOL + CTX group. CTX was intraperitoneally injected and different doses of CTOL were given by gavages. After 6 weeks of continuous administration,- 收稿日期:2022-10-25 基金项目:河北省医学科学研究课题计划(20211152);河北大学医学学科培育项目(2020B16); 2022年国家级大学生创新创业训练计划项目(202210075017) 第一作者:石炳烨(1983—),男,河北保定人,河北大学附属医院主治医师,河北大学在读硕士研究生,主要从事免疫药理研究.E-mail:2435231348@qq.com 通信作者:靳文勋(1978—),男,河北曲阳人,保定脑血管病医院副主任医师,主要从事神经肿瘤免疫研究.E-mail:jwx780602@163.com第5期石炳烨等:复方太岁口服液体内外抗肿瘤及免疫调节作用 mice were sacrificed, then tumor tissues and spleens were weighed. The tumor inhibition rate and spleen index were calculated and IL-2 and IFN-γ of serum were measured by ELISA. The proliferation of SGC7901 and Hela cells were inhibited by different concentrations of CTOL, and the cytotoxic effect of CTOL on different tumor cells was dose-dependent. The tumor weight of each experimental group was significantly lower than that of the model group(P<0.05), and the tumor inhibition rate of the high-dose of CTOL + CTX group was the highest(70.90%). The spleen index, IL-2 and IFN-γ levels in low-dose and high-dose of CTOL + CTX groups were significantly higher than those in the CTX group(P<0.05). CTOL can inhibit the growth of tumors in vitro and in vivo, promote the secretion of IL-2 and IFN-γ and has protective effect on the damage to spleen caused by CTX in tumor-bearing mice.
    Isolation and identification of secondary metabolites of Fusarium equiseti
    PAN Huayang, LIU Huaguang, QI Zexin, ZHAO Xiaolong, LUO Duqiang
    2023, 43(5):  512-516.  DOI: 10.3969/j.issn.1000-1565.2023.05.010
    Asbtract ( 170 )   PDF (625KB) ( 112 )  
    References | Related Articles | Metrics
    In order to find compounds with new structures and significant pharmacological effects, three compounds 1, 2 and 3 were isolated and identified from the secondary metabolites of the endophytic fungus Fusarium equiseti from Harmonia axyridis by modern isolation methods. Among them, compounds 1(equisetin)and 2(epi-equisetin)are a pair of epiisomers, and 3(6-methoxy-droperylene)belongs to steroids. In vitro protein tyrosine phosphatase 1B(PTP1B)inhibitory activity test showed that compounds 1 and 2 had certain inhibitory activity on PTP1B, and IC50 values were(8.73 ± 0.03),(12.88 ± 0.16)μg/mL. It provides potential drug lead compounds for the development of new PTP1B inhibitors.
    Supervisor synthesis for Petri nets with unobservable and uncontrollable transitions
    HAO Jinyuan,GAO Limin,RAN Ning,HUANG Miao,HAO Zhenming
    2023, 43(5):  517-524.  DOI: 10.3969/j.issn.1000-1565.2023.05.011
    Asbtract ( 138 )   PDF (765KB) ( 55 )  
    References | Related Articles | Metrics
    A controller synthesis method based on integer linear programming is proposed to solve the forbidden state problem of discrete event systems with both unobservable and uncontrollable events. Firstly, according to the structural characteristics of Petri net, a set of linear constraints for all unobservable transitions and uncontrollable transitions are constructed, and the given constraints were abstracted into integer linear programming problems. Secondly, the allowable linear constraint is obtained by resolving the integer linear programming problem. Finally, the controller is designed based on library invariants and the transformed allowable linear constraints are integrated into Petri net. The simulation- DOI:10.3969/j.issn.1000-1565.2023.05.011含不可观和不可控变迁Petri网的控制器综合方法郝晋渊1,高丽敏2,冉宁2,3,黄淼2,郝真鸣3,4(1.河北大学-中央兰开夏传媒与创意学院,河北 保定 071002;2.河北大学 电子信息工程学院 节能技术研发中心,河北 保定 071002;3.河北大学 电子信息工程学院,河北 保定 071002;4.河北大学 电子信息工程学院 物联网智能技术研究中心,河北 保定 071002)摘 要:针对同时含有不可观和不可控事件的离散事件系统禁止状态问题,提出了一种基于整数线性规划的控制器综合方法.首先,依据Petri网的结构特性构建所有不可观变迁及不可控变迁需满足的线性约束条件集合,将给定约束条件抽象为整数线性规划问题.其次,通过求解整数线性规划问题得到允许线性约束.最后,基于库所不变量的方法设计控制器并将转换后的允许线性约束综合到Petri网中.实验仿真表明提出的方法简单高效,能够保障系统不进入禁止状态,对离散事件系统监控问题具有理论指导意义.关键词:Petri网;禁止状态;约束转换;整数线性规划中图分类号:TP11 文献标志码:A 文章编号:1000-1565(2023)05-0517-08Supervisor synthesis for Petri nets with unobservable and uncontrollable transitionsHAO Jinyuan1,GAO Limin2,RAN Ning2,3,HUANG Miao2,HAO Zhenming3,4(1. HBU-UCLAN School of Media, Communication and Creative Industries, Hebei University, Baoding 071002,China;2. Lab of Energy-Saving Technology, College of Electronic Informational Engineering, Hebei University, Baoding 071002, China; 3. College of Electronic Informational Engineering, Hebei University, Baoding 071002,China; 4. Laboratory of IoT Technology, College of Electronic Informational Engineering, Hebei University, Baoding 071002, China)Abstract: A controller synthesis method based on integer linear programming is proposed to solve the forbidden state problem of discrete event systems with both unobservable and uncontrollable events. Firstly, according to the structural characteristics of Petri net, a set of linear constraints for all unobservable transitions and uncontrollable transitions are constructed, and the given constraints were abstracted into integer linear programming problems. Secondly, the allowable linear constraint is obtained by resolving the integer linear programming problem. Finally, the controller is designed based on library invariants and the transformed allowable linear constraints are integrated into Petri net. The simulation- 收稿日期:2022-03-02 基金项目:国家自然科学基金资助项目(62373132);教育部“春晖计划”合作科研项目(HZKY20220257);中央引导地方科技发展基金资助项目(236Z1602G);河北省高等学校科学技术研究项目(BJ2021008);河北省引进留学人员资助项目(C20190319);河北大学"一省一校"专项基金资助项目(801260201137) 第一作者:郝晋渊(1990—),女,河北保定人,河北大学讲师,主要从事人工智能、信息技术、新媒体传播等研究.E-mail:hjy@hbu.edu.cn 通信作者:冉宁(1978—),男,河北丰宁人,河北大学副教授,主要从事离散事件系统、监控理论等研究.E-mail:ranning87@hotmail.com第5期郝晋渊等:含不可观和不可控变迁Petri网的控制器综合方法results indicate that the suggested technique is uncomplicated and efficient, and can ensure that the system does not enter forbidden state, which has theoretical guiding significance for discrete event system monitoring.
    3D PET/MRI image fusion based on improved structure tensor
    ZHENG Wei, XIA Xueting, ZHANG Xiaodan, MA Zepeng
    2023, 43(5):  525-538.  DOI: 10.3969/j.issn.1000-1565.2023.05.012
    Asbtract ( 140 )   PDF (1653KB) ( 92 )  
    References | Related Articles | Metrics
    The fusion of magnetic resonance imaging(MRI)and positron emission computed tomography(PET)can achieve the prevention and diagnosis of Alzheimers disease(AD). Although the current three-dimensional image fusion algorithm based on structural tensor has good spatial characteristics, it can also represent the structural information of the image. This paper proposes structure tensor based on 3D ISobel and double-objective marine predator algorithm(IST), which improves the reliability and stability of the decomposition and makes the detailed information fully expressed. In this paper, the edge region fusion rule of Joint Weight Sum of 3D Energy And Modified Laplacian And Trace Phase Consistency(ETPC)is proposed, which fully describes the local region feature distribution of the fused - DOI:10.3969/j.issn.1000-1565.2023.05.012基于改进结构张量的三维PET/MRI图像融合郑伟1,夏雪婷1,张晓丹2,马泽鹏3(1.河北大学 电子信息工程学院,河北 保定 071002;2.河北大学附属医院 超声诊断科,河北 保定 071000;3.河北大学附属医院 放射科,河北 保定 071000)摘 要:将核磁共振成像(magnetic resonance imaging, MRI)与正电子发射断层成像(positron emission computed tomography, PET)进行融合,可以实现阿尔茨海默病(Alzheimers disease, AD)的预防与诊断.提出了基于3D ISobel与双目标海洋捕食者的结构张量(ISobel and double-objective marine predator algorithm based on structure tensor, IST)分解算法,提高了分解的可靠性与稳定性,使细节信息充分表达.提出了联合三维拉普拉斯加权能量的迹值相位一致性(joint weight sum of 3d energy and modified laplacian and trace phase congruency, ETPC)的边缘区融合规则,充分描述了融合图像局部区域特征分布.融合结果表明,基于改进结构张量的三维PET/MRI图像融合算法解决了结构张量分解欠缺可靠性、融合图像细节信息不充分、局部特征描述不完善的问题,在主观评价和客观评价方面都要优于其他的空间域和变换域的融合方法.关键词:图像融合;结构张量;海洋捕食者算法;三维PET/MRI;相位一致性中图分类号:TP391.9 文献标志码:A 文章编号:1000-1565(2023)05-0525-143D PET/MRI image fusion based on improved structure tensorZHENG Wei1, XIA Xueting1, ZHANG Xiaodan2, MA Zepeng3(1.College of Electronic Information Engineering, Hebei University, Baoding 071002, China;2. Department of Ultrasound Diagnosis, Affiliated Hospital of Hebei University, Baoding 071000, China;3. Department of Radiology, Affiliated Hospital of Hebei University, Baoding 071000, China)Abstract: The fusion of magnetic resonance imaging(MRI)and positron emission computed tomography(PET)can achieve the prevention and diagnosis of Alzheimers disease(AD). Although the current three-dimensional image fusion algorithm based on structural tensor has good spatial characteristics, it can also represent the structural information of the image. This paper proposes structure tensor based on 3D ISobel and double-objective marine predator algorithm(IST), which improves the reliability and stability of the decomposition and makes the detailed information fully expressed. In this paper, the edge region fusion rule of Joint Weight Sum of 3D Energy And Modified Laplacian And Trace Phase Consistency(ETPC)is proposed, which fully describes the local region feature distribution of the fused - 收稿日期:2023-01-06 基金项目:河北省自然科学基金资助项目( F2020201025; H2020201021);河北省高等学校科学技术研究项目(BJ2020030);河北大学附属医院青年科研基金资助项目(2021Q021;2022QB28) 第一作者:郑伟(1972—),女,黑龙江兰西人,河北大学教授,博士,主要从事图像处理与分析、图像安全通信、图像加密和隐藏研究. E-mail:147685650@qq.com 通信作者:马泽鹏(1989—),男,河北保定人,河北大学附属医院放射科主治医师,主要从事脑部和心脏疾病的CT、MR、fMRI等的鉴别诊断研究.E-mail:mzpdan@163.com第5期郑伟等:基于改进结构张量的三维PET/MRI图像融合image. The 3D PET/MRI image fusion algorithm based on improved structural tensor solves the problems of the lack of reliability of structural tensor decomposition, insufficient detail information of fusion image, and imperfect description of local features, and it is better than other fusion methods of spatial domain and transform domain in terms of subjective evaluation and objective evaluation.
    Detection methods of construction tower crane based on DSOD
    SHAN Tengfei,WANG Xintong,HUA Yifeng,KANG Biao,HOU Xueliang
    2023, 43(5):  539-545.  DOI: 10.3969/j.issn.1000-1565.2023.05.013
    Asbtract ( 119 )   PDF (1018KB) ( 50 )  
    References | Related Articles | Metrics
    In order to solve the problems of small detection range, complex detection process and susceptiblility to interference, a new detection method of construction tower crane is proposed by using DSOD(deeply supervised object detector)algorithm without model pre training. Firstly, a large number of clear tower crane images are collected from the construction site by camera to establish the data sets, and then the DSOD model is trained repeatedly to achieve the ideal convergence effect. Finally, the performance of this model is evaluated under different conditions(shooting angle, shooting distance and occlusion degree), and it is compared with the previous detection methods. The experimental results show that DSOD does have obvious advantages in detection accuracy and detection speed, and under the conditions of “front shooting”, “medium distance shooting” and “shielding degree less than 50%”, the precision and recall rate of tower crane detection can reach more than 90%, which provides a new idea for construction managers to solve practical problems of the project.
    Application of object detection algorithm in pathology diagnosis of lung cancer
    WU Jianguo,YANG Xiaoru,WANG Pan,WU Junfang,LI Ruikai
    2023, 43(5):  546-552.  DOI: 10.3969/j.issn.1000-1565.2023.05.014
    Asbtract ( 147 )   PDF (1596KB) ( 108 )  
    References | Related Articles | Metrics
    Object detection based on deep learning has been widely studied in many fields such as transportation and military, and has achieved remarkable results. In order to further study its usability in medical image diagnosis, two classical models of object detection algorithms, SSD and Faster RCNN, are proposed to appliy to the lesion detection of lung cancer pathological images. The experimental comparison shows that the average processing time of Faster RCNN is about 4.6 times longer than that of SSD, but the recognition accuracy and precision are higher than that of SSD, and the model performance of Faster RCNN is much better. The research results show that the object detection algorithm can realize the intelligent diagnosis of lung cancer pathological images and improve the diagnosis rate of lung cancer.
    Coverage optimization for WSNs based on uncovered vertices
    YIN Boran,MA Jun,CHEN Bohang,WANG Hongchen
    2023, 43(5):  553-560.  DOI: 10.3969/j.issn.1000-1565.2023.05.015
    Asbtract ( 141 )   PDF (1663KB) ( 114 )  
    References | Related Articles | Metrics
    In order to further improve the coverage of wireless sensor networks(WSNs)and reduce the number of mobile deployment iterations, this work improves the virtual force between sensors and the virtual force algorithm of Tyson polygon vertices. In view of the discontinuity of the mathematical model of the existing virtual force algorithm, Hookes Law is used heve as the model, so that the virtual force on the sensor is linearly related to the distance. When the distance between sensors is greater than 2RS, virtual force is applied to the nearest sensor node by using the uncovered vertices of Tyson polygons. At the same time, this algorithm lets the step size of the virtual force determine the movement step size of the sensor. The simulation results show that this algorithm can increase the coverage from 93.5% to 99.7%, and reduce the number of iterations to less than 25%. The algorithm in this paper plays an active role in the coverage research of homogeneous wireless sensor networks.