Journal of Hebei University (Natural Science Edition) ›› 2019, Vol. 39 ›› Issue (5): 498-503.DOI: 10.3969/j.issn.1000-1565.2019.05.009

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Quantitative determination and comparison the contents of tannic acid and resveratrol in red wine

ZHANG Yuanyuan1, LI Jiajia2, HAN Xue1, ZHANG Jianping3, CHU Li1   

  1. 1. School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang 050200, China; 2. Department of pharmacy, The Fourth Hospital of Shifiazhuang, Shijiazhuang 050011, China; 3. School of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China
  • Received:2018-06-29 Online:2019-09-25 Published:2019-09-25

Abstract: To determine the content of tannic acid and resveratrol in red wine, and to identify the main functional substances in red wine about the “French paradox”, the high performance liquid chromatography(HPLC)was used to quantitative determine the contents of tannic acid and resveratrol in four different brands red wine. The results showed that the content of tannic acid in red wine was 0.81~1.44 mg /mL, and the content of resveratrol was 0.14~2.49 mg /L, that is to say, the content of tannin was about 103 times higher than resveratrol. Considering the more and more pharmacological studies on the cardiovascular activity of tannic acid, the results suggested that tannic acid may also be the main functional substance to explain the French paradox.

Key words: HPLC, red wine, tannic acid, resveratrol, French paradox

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