Top Down Articles

Published in last 1 year | In last 2 years| In last 3 years| All| Most Downloaded in Recent Month | Most Downloaded in Recent Year|

In last 2 years

Please wait a minute...


For Selected: Download Citations EndNote Ris BibTeX Toggle Thumbnails

Select

Atomic layer deposition process of SnO2 and TiO2 films on perovskite materials LUO Hao, ZHANG Huiyu, LIU Hongyan, LIU Haixu, LU Wanbing Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 370-375.   DOI: 10.3969/j.issn.1000-1565.2022.04.006 Abstract （664）      PDF（pc） （999KB）（559）       Knowledge map    Save The diffusion reaction between the metal electrode and the halogen is an important factor of perovskite solar cell(PSC)degradation. Using atomic layer deposition(ALD)technology to deposit a dense buffer layer with good electrical performance between metal electrode and perovskite active layer is one of the preferred solutions to solve the above problems. This work studies the process compatibility of SnO2 and TiO2 films deposited on organohalide perovskite materials using ALD technology. The effects of tetra(dimethylamino)titanium(TDMATi)and tetra(dimethylamino)tin(TDMASn)pulses and water pulses at different temperatures on the structure of perovskite films are investigated by X-ray diffraction and ultraviolet-visible absorption spectroscopy, and the influence of the pulse times of different precursor sources and purging time on the film deposition mode are analyzed, and the optimized ALD processes of SnO2- DOI:10.3969/j.issn.1000-1565.2022.04.006SnO2和TiO2薄膜在钙钛矿材料上的原子层沉积工艺罗浩,张慧玉,刘红燕,刘海旭,路万兵(河北大学 物理科学与技术学院,河北省光电信息材料重点实验室,河北 保定 071002)摘 要:金属电极与卤素之间的扩散反应是造成钙钛矿太阳电池(PSC)衰退的重要因素,而利用原子层沉积(ALD)技术在金属电极和钙钛矿活性层之间沉积致密且电学性能良好的缓冲层,是解决上述问题的优选方案之一.本文主要研究了利用ALD技术在金属有机卤化物钙钛矿材料上沉积SnO2和TiO2薄膜的工艺兼容性问题.通过X线衍射和紫外-可见吸收光谱等技术,表征了分别作为钛源和锡源的四(二甲氨基)钛(TDMATi)和四(二甲氨基)锡(TDMASn)脉冲以及不同温度下水脉冲对钙钛矿薄膜结构的影响,分析了不同前驱体源的脉冲及吹扫时间对薄膜沉积模式的影响,获得了与钙钛矿材料相兼容的SnO2和TiO2薄膜的优化ALD工艺.将优化后的SnO2和TiO2薄膜ALD工艺应用于倒置PSC制备,对电池的J-V曲线和大气环境下的稳定性测试结果表明,基于ALD技术沉积的SnO2和TiO2缓冲层的引入,使得PSC的稳定性明显改善,而且其功率转换效率也有所提高.关键词:钙钛矿;原子层沉积;工艺兼容性;稳定性中图分类号:O469 文献标志码:A 文章编号:1000-1565(2022)04-0370-06Atomic layer deposition process of SnO2 and TiO2 films on perovskite materialsLUO Hao, ZHANG Huiyu, LIU Hongyan, LIU Haixu, LU Wanbing(Hebei Key Laboratory of Optic-Electronic Information and Materials, College of Physics Science and Technology, Hebei University, Baoding 071002, China)Abstract: The diffusion reaction between the metal electrode and the halogen is an important factor of perovskite solar cell(PSC)degradation. Using atomic layer deposition(ALD)technology to deposit a dense buffer layer with good electrical performance between metal electrode and perovskite active layer is one of the preferred solutions to solve the above problems. This work studies the process compatibility of SnO2 and TiO2 films deposited on organohalide perovskite materials using ALD technology. The effects of tetra(dimethylamino)titanium(TDMATi)and tetra(dimethylamino)tin(TDMASn)pulses and water pulses at different temperatures on the structure of perovskite films are investigated by X-ray diffraction and ultraviolet-visible absorption spectroscopy, and the influence of the pulse times of different precursor sources and purging time on the film deposition mode are analyzed, and the optimized ALD processes of SnO2- 收稿日期:2021-01-07 基金项目:河北省自然科学基金资助项目(E2021201014;F2017201101);中央引导地方科技发展资金项目(206Z1102G) 第一作者:罗浩(1992—),男,吉林松原人,河北大学在读硕士研究生,主要从事新能源光电功能材料研究. E-mail:1683209529@qq.com 通信作者:路万兵(1980—),男,河北保定人,河北大学副教授,博士,主要从事新能源光电功能材料研究.E-mail:wanbinglu@hbu.edu.cn第4期罗浩等:SnO2和TiO2薄膜在钙钛矿材料上的原子层沉积工艺and TiO2 films compatible with perovskite materials are obtained. The inverted PSCs are fabricated by using the optimized SnO2 and TiO2 film ALD process, and the J-V curves and stability tests in atmospheric environment for the PSCs show that the introduction of SnO2 and TiO2 buffer layers deposited by ALD technology significantly improves the stability of PSCs, and their power conversion efficiency has also been improved. Reference | Related Articles | Metrics | Comments（0）

Select

Effect of ultrasonic on mouse behavior and its mechanism in rodent repeller SHAO Jianze, WEI Mengyi, CHEN Kai, ZHANG Yuming, LIU Fengsong Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 504-510.   DOI: 10.3969/j.issn.1000-1565.2022.05.009 Abstract （554）      PDF（pc） （1017KB）（496）       Knowledge map    Save In order to explore the effect of ultrasonic on mouse behavior and the mechanism of action of ultrasonic mouse repellent, a simple method for evaluating the effect of ultrasonic mouse repellent was established, which employed a commercially ultrasonic rodent repeller to investigate its effect on repelling mice in an open field.The spontaneous activity,elevated plus maze, and the sucrose water preference experiment were used to count the behavioral changes of mice under the stress of ultrasonic generator and ultrasonic mouse repellent. Results showed that the rodent repellent could drive away the mice during 10 d experiments. Continuous 10 d treatment with the ultrasonic repellent can cause the mice to decline in their ability to move and explore, induce anxiety and depression, and the above-mentioned changes caused by the ultrasonic generator treatment are more significant. This study can provide data support for the mechanism of ultrasonic repellent. It can also provide technical reference for the effect evaluation and research and development of related mouse repellents. Reference | Related Articles | Metrics | Comments（0）

Select

Existence and uniqueness of solutions for a class of dynamic Melan equations TANG Mengying, ZHANG Jian, WANG Yongda Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 449-453.   DOI: 10.3969/j.issn.1000-1565.2022.05.001 Abstract （408）      PDF（pc） （327KB）（408）       Knowledge map    Save To solve a dynamic Melan equation, which is viewed as a beam model for dynamic suspension bridges, Galerkin’s method and the contraction mapping principle are applied to the nonlinear non-local Melan equation. The existence and uniqueness results are obtained. Reference | Related Articles | Metrics | Comments（0）

Select

Physical properties of La0.67Sr0.33MnO3/PbZr0.4Ti0.6O3/La0.67Sr0.33 MnO3 epitaxial ferroelectric capacitor XUE Yinggang,MENG Hao,WANG Zhaowen,ZHAO Wenze,LIU Baoting,DAI Xiuhong Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 364-369.   DOI: 10.3969/j.issn.1000-1565.2022.04.005 Abstract （270）      PDF（pc） （755KB）（351）       Knowledge map    Save La0.67Sr0.33MnO3(LSMO)/PbZr0.4Ti0.6O3(PZT)/LSMO heterostructure was prepared on SrTiO3(STO)substrate, in which LSMO films were prepared by pulsed laser deposition and PZT film was prepared by Sol-Gel method. The LSMO/PZT/LSMO heterostructure was characterized in terms of its structural and physical properties. X-ray diffraction(XRD)analysis established that both LSMO and PZT were grown epitaxially on STO substrate. The LSMO/PZT/LSMO capacitor possessed very good ferroelectric hysteresis property and its remnent polarization and coercive voltage of the LSMO/PZT/LSMO capacitor, measured at 5 V, were 26.9 μC/cm2 and 2.5 V, respectively. The LSMO/PZT/LSMO capacitor exhibited very good fatigue resistant property. The leakage current density of the capacitor measured at 5 V was 7.4×10-6 A/cm2, and it met the ohmic conduction mechanism below 2.9 V, and space charge limited current(SCLC)conduction from 2.9 V to 5 V.- DOI:10.3969/j.issn.1000-1565.2022.04.005La0.67Sr0.33MnO3/PbZr0.4Ti0.6O3/La0.67Sr0.33MnO3外延铁电电容器物理性能薛迎港1,孟浩1,王照文1,赵文泽2,刘保亭1,代秀红1(1.河北大学 物理科学与技术学院,河北 保定 071002;2.河北大学 电子信息工程学院,河北 保定 071002)摘 要:采用脉冲激光沉积法制备La0.67Sr0.33MnO3(LSMO)薄膜,溶胶-凝胶法制备PbZr0.4Ti0.6O3(PZT)薄膜,在SrTiO3(STO)基片上制备了LSMO/PZT/LSMO异质结电容器.X线衍射(XRD)研究表明LSMO和PZT薄膜在STO基片上实现了外延生长.LSMO/PZT/LSMO电容器具有良好的铁电性能,在5 V测试电压下,剩余极化强度为26.9 μC/cm2,矫顽电压为2.5 V,LSMO/PZT/LSMO电容器显示出了良好的抗疲劳性能.5 V电压下电容器的漏电流密度为7.4×10-6 A/cm2,在0~2.9 V为欧姆导电机制,2.9~5 V满足空间电荷限制电流(SCLC)导电机制. 关键词:铁电电容器;锆钛酸铅;镧锶锰氧;脉冲激光沉积法;溶胶-凝胶法;漏电机理中图分类号:O469 文献标志码:A 文章编号:1000-1565(2022)04-0364-06Physical properties of La0.67Sr0.33MnO3/PbZr0.4Ti0.6O3/La0.67Sr0.33MnO3 epitaxial ferroelectric capacitorXUE Yinggang1,MENG Hao1,WANG Zhaowen1,ZHAO Wenze2,LIU Baoting1,DAI Xiuhong1(1. College of Physics Science and Technology, Hebei University, Baoding 071002, China;2. College of Electronic and Information Engineering, Hebei University, Baoding 071002, China)Abstract: La0.67Sr0.33MnO3(LSMO)/PbZr0.4Ti0.6O3(PZT)/LSMO heterostructure was prepared on SrTiO3(STO)substrate, in which LSMO films were prepared by pulsed laser deposition and PZT film was prepared by Sol-Gel method. The LSMO/PZT/LSMO heterostructure was characterized in terms of its structural and physical properties. X-ray diffraction(XRD)analysis established that both LSMO and PZT were grown epitaxially on STO substrate. The LSMO/PZT/LSMO capacitor possessed very good ferroelectric hysteresis property and its remnent polarization and coercive voltage of the LSMO/PZT/LSMO capacitor, measured at 5 V, were 26.9 μC/cm2 and 2.5 V, respectively. The LSMO/PZT/LSMO capacitor exhibited very good fatigue resistant property. The leakage current density of the capacitor measured at 5 V was 7.4×10-6 A/cm2, and it met the ohmic conduction mechanism below 2.9 V, and space charge limited current(SCLC)conduction from 2.9 V to 5 V.- 收稿日期:2021-08-31 基金项目:国家自然科学基金资助项目(11374086);河北省自然科学基金资助项目(E2014201188;A2018201168) 第一作者:薛迎港(1997—),男,河北石家庄人,河北大学在读硕士研究生,主要从事铁电薄膜及器件方向研究.E-mail:yinggang_xue@hotmail.com 通信作者:代秀红(1978—)女,河北定州人,河北大学副教授,主要从事钙钛矿结构超导、铁电、介电等氧化物薄膜及器件方向研究.E-mail:daixiuhong@hbu.edu.cn第4期薛迎港等:La0.67Sr0.33MnO3/PbZr0.4Ti0.6O3/La0.67Sr0.33MnO3外延铁电电容器物理性能 Reference | Related Articles | Metrics | Comments（0）

Select

A numerical method and its fast implementation for multi-term fractional nonlinear wave equations SHAO Linxin, SHEN Zhuoyang, MA Geqinzhou, MIN Jie, HUANG Jianfei Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 454-462.   DOI: 10.3969/j.issn.1000-1565.2022.05.002 Abstract （276）      PDF（pc） （490KB）（322）       Knowledge map    Save A linearized numerical method for multi-term time fractional nonlinear wave equations with a spatial fourth-order derivative is derived. To avoid solving the nonlinear system of equations, a linearized technique is applied to discretize the nonlinear term. Then, the convergence of this presented method is rigorously proved with the first-order accuracy in time and the fourth-order accuracy in space. It is worth mentioning that the presented method can handle the initial singularity, and can be fast calculated by the sum-of-exponentials technique. Finally, numerical experiments are given to verify the effectiveness of this method and the correctness of the theoretical results. Reference | Related Articles | Metrics | Comments（0）

Select

Effect of the elememtal ratio of Cd to Se on the luminescent properties of CdSe quantum dots DING Yanan, ZHENG Yibo, LAI Weidong, LI Shuguang, WEI Zhiren, LI Zhiqiang, WANG Chunsheng Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 463-467.   DOI: 10.3969/j.issn.1000-1565.2022.05.003 Abstract （311）      PDF（pc） （827KB）（279）       Knowledge map    Save Cadmium selenide(CdSe)quantum dots have the advantages of high fluorescence quantum yield, good stability and easy spectrum adjustment. They have broad application prospects in the fields of light-emitting diodes, solar cells and fluorescent labeling etc. It is of great significance to study the effects of different process conditions on their properties. Using mercaptopropionic acid(3-MPA)as coating agent, a series of CdSe quantum dots have been prepared by aqueous reflux reaction at 100 ℃ for 120 min. The changes of morphology, band gap and optical properties of the samples with different elemental ratio of Cd to Se are discussed. The size of CdSe quantum dots is about 2.19 nm to 2.57 nm. The strongest excitation peak locates at 431 nm, the emission peak is at 561 nm, and the absorption spectrum blueshifts from 460 nm to 450 nm, indicating that the elemental ratio of Cd to Se has great influence on the properties of CdSe quantum dots. Reference | Related Articles | Metrics | Comments（0）

Select

Study on visible light photocatalytic degradation of dibutyl phthalate in water LEI Yuan, LIU Guisui, ZHU Aixue, LI Muyuan, LIU Pengyan Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 474-482.   DOI: 10.3969/j.issn.1000-1565.2022.05.005 Abstract （302）      PDF（pc） （1283KB）（265）       Knowledge map    Save The composite material g-C3N4/Bi4O5I2 was synthesized and characterized. The influencing factors of photocatalytic degradation of dibutyl phthalate(DBP)in water under visible light irradiation using the as-synthesized catalyst were studied, including catalyst dosage, initial solution concentration, pH and common anion Cl-, NO-3 and SO2-4 in water. Through the analysis of degradation products, the possible degradation mechanism was proposed. The results showed that the optimum dosage of g-C3N4/Bi4O5I2 was 0.6 g/L. The higher the initial concentration in the study range, the lower the degradation rate. When the solution was neutral, the photocatalytic degradation effect of DBP in water was the best. Cl-, NO-3 and SO2-4 all inhibited the photocatalytic degradation to a certain extent. Through the analysis of the degradation products after the reaction, it is speculated that the side chain of DBP breaks first under the attack of active substances, and then continues to degrade into small molecular substances. The research results have important practical significance and reference value for the removal of phthalates in water environment. - DOI:10.3969/j.issn.1000-1565.2022.05.005可见光催化降解水中邻苯二甲酸二丁酯雷源1,刘桂随2,朱爱雪2,李牧原2,刘芃岩1(1.河北大学 生态环境学院(筹),河北 保定 071002;2.河北大学 化学与环境科学学院,河北 保定 071002)摘 要:合成了复合材料g-C3N4/Bi4O5I2,并进行了表征分析,以其为催化剂,研究了可见光照射下,水中邻苯二甲酸二丁酯(DBP)光催化降解的影响因素:催化剂投加量、溶液初始浓度、pH及水中常见阴离子Cl-、NO-3和SO2-4等,并通过对降解产物的分析,提出了可能的降解机理. 结果表明:g-C3N4/Bi4O5I2的最佳投加量为0.6 g/L;在研究范围内初始浓度越高,降解率越低;当溶液为中性时,对水中DBP的光催化降解效果最好;Cl-、NO-3和SO2-4都对光催化降解产生了一定的抑制作用. 通过对反应后降解产物的分析,推测DBP是在活性物质的攻击下,侧链先发生断裂,再继续降解为小分子物质. 研究结果对水环境中邻苯二甲酸酯类的去除具有重要的实际意义和参考价值. 关键词:可见光;邻苯二甲酸二丁酯;光催化降解;g-C3N4/Bi4O5I2中图分类号:X703 文献标志码:A 文章编号:1000-1565(2022)05-0474-09Study on visible light photocatalytic degradation of dibutyl phthalate in water LEI Yuan1, LIU Guisui2, ZHU Aixue2, LI Muyuan2, LIU Pengyan1(1. School of Eco-Environment, Hebei University, Baoding 071002,China; 2. College of Chemistry and Environmental Science, Hebei University, Baoding 071002,China)Abstract: The composite material g-C3N4/Bi4O5I2 was synthesized and characterized. The influencing factors of photocatalytic degradation of dibutyl phthalate(DBP)in water under visible light irradiation using the as-synthesized catalyst were studied, including catalyst dosage, initial solution concentration, pH and common anion Cl-, NO-3 and SO2-4 in water. Through the analysis of degradation products, the possible degradation mechanism was proposed. The results showed that the optimum dosage of g-C3N4/Bi4O5I2 was 0.6 g/L. The higher the initial concentration in the study range, the lower the degradation rate. When the solution was neutral, the photocatalytic degradation effect of DBP in water was the best. Cl-, NO-3 and SO2-4 all inhibited the photocatalytic degradation to a certain extent. Through the analysis of the degradation products after the reaction, it is speculated that the side chain of DBP breaks first under the attack of active substances, and then continues to degrade into small molecular substances. The research results have important practical significance and reference value for the removal of phthalates in water environment. - 收稿日期:2021-05-15 基金项目:国家自然科学基金资助项目(21377033);河北省自然科学基金资助项目(B2021201031) 第一作者:雷源(1997—),女,河北邢台人,河北大学在读硕士研究生,主要从事环境污染化学方向研究.E-mail:2317535846@qq.com 通信作者:刘芃岩(1964—),女,河北保定人,河北大学教授,博士生导师,主要从事环境中典型污染物的生成降解与迁移转化研究.E-mail:hbupyliu@163.com第5期雷源等:可见光催化降解水中邻苯二甲酸二丁酯 Reference | Related Articles | Metrics | Comments（0）

Select

Vibration characteristics analysis of the inner race fault of axlebox bearing under wheel-rail excitation DENG Feiyue,WANG Hongli,GAO Ruiyang,LI Hao Journal of Hebei University(Natural Science Edition)    2023, 43 (6): 561-570.   DOI: 10.3969/j.issn.1000-1565.2023.06.001 Abstract （339）      PDF（pc） （2669KB）（253）       Knowledge map    Save Wheel-rail complex excitation has a significant effect on the dynamic behavior of faulty axlebox bearing during the train operation. Firstly, this paper uses the Universal Mechanism(UM)software to establish a vehicle-track dynamic model, and obtains the vertical, longitudinal and lateral loads of axlebox bearing under wheel-rail complex excitation based on the verification of vehicle models for stability, smoothness and safety. Secondly, the dynamic model of axlebox bearing with inner race spalling is established via Solidworks and ADAMAS softwares, and the accuracy of the proposed model is verified by comparison with the axlebox bearing experiments on the roll-vibration test bench. The dynamic simulation analysis shows that the contact load of the roller and inner race of the fault side is greater than that of the non-faulty side and the normal bearing, the cage vibration of the fault side is greater than that of- DOI:10.3969/j.issn.1000-1565.2023.06.001轮轨激励条件下轴箱轴承内圈故障振动特性分析邓飞跃1,2,王红力1,高瑞洋1,李浩1(1.石家庄铁道大学 机械工程学院,河北 石家庄 050043;2.河北省工程机械动力与传动控制重点实验室,河北 石家庄 050043)摘 要:高速列车运行过程中,轮轨复杂激励会对轴箱轴承的动力学行为产生不可忽视的影响.首先利用UM(universal mechanism)软件建立车辆-轨道动力学模型,在对车辆模型进行稳定性、平稳性和安全性验证的基础上,获取了复杂激励下轴箱轴承所受的垂向、纵向和横向载荷;然后,通过Solidworks软件和ADAMS软件建立了轴箱轴承内圈剥离故障动力学模型,通过与滚振实验台轴箱轴承实验对比,验证了所提模型的准确性.通过动力学仿真分析可知,轴箱轴承故障侧的滚子与内圈接触载荷大于非故障侧与正常轴承,故障侧保持架的振动大于非故障侧与正常轴承,内圈故障冲击加剧了轴承保持架与外圈的质心波动.最后,进一步对比考虑轮轨激励下与定载荷下故障轴承仿真结果发现,受轮轨激励的影响轴承内部各个元件间的接触载荷显著增大,轴承保持架与外圈质心运动轨迹盒维数显著增大.研究成果对揭示实际工况下高速动车组轴箱轴承内部元件振动特性规律具有重要意义.关键词:轴箱轴承;轮轨激励;振动特性;内圈故障中图分类号:TH17 文献标志码:A 文章编号:1000-1565(2023)06-0561-10Vibration characteristics analysis of the inner race fault of axlebox bearing under wheel-rail excitationDENG Feiyue1,2,WANG Hongli1,GAO Ruiyang1,LI Hao1(1.School of Mechanical Engineering, Shijiazhuang Tiedao University, Shijiazhuang 050043,China;2.Hebei Key Laboratory of Mechanical Power and Transmission Control,Shijiazhuang 050043,China)Abstract: Wheel-rail complex excitation has a significant effect on the dynamic behavior of faulty axlebox bearing during the train operation. Firstly, this paper uses the Universal Mechanism(UM)software to establish a vehicle-track dynamic model, and obtains the vertical, longitudinal and lateral loads of axlebox bearing under wheel-rail complex excitation based on the verification of vehicle models for stability, smoothness and safety. Secondly, the dynamic model of axlebox bearing with inner race spalling is established via Solidworks and ADAMAS softwares, and the accuracy of the proposed model is verified by comparison with the axlebox bearing experiments on the roll-vibration test bench. The dynamic simulation analysis shows that the contact load of the roller and inner race of the fault side is greater than that of the non-faulty side and the normal bearing, the cage vibration of the fault side is greater than that of- 收稿日期:2023-06-13 基金项目:国家自然科学基金资助项目(12272243); 河北省研究生专业学位精品教学案例库项目(KCJPZ2023037) 第一作者:邓飞跃(1985—),男,河北石家庄人,石家庄铁道大学副教授,博士,博士生导师,主要从事机电系统故障诊断与状态监测研究.E-mail:dengfy@stdu.edu.cn第6期邓飞跃等:轮轨激励条件下轴箱轴承内圈故障振动特性分析the non-faulty side and the normal bearing, and the fault impact aggravates the trajectory of the mass center fluctuation of the bearing cage and outer ring. Finally, further comparison of the simulation results under the consideration of wheel-rail excitation and the constant load condition reveals that the contact load between the bearing components is significantly increased by the wheel-rail excitation,and the trajectories of the mass center for the bearing cage and outer ring fluctuate more drastically. The research results are of great significance in revealing the vibration characteristics law of the bearing internal components of faulty axlebox bearing under actual operating conditions. Reference | Related Articles | Metrics | Comments（0）

Select

Analysis of community structure of macrobenthic invertebrates in Baiyangdian Basin WU Zhixin, WANG Xi, LIU Yuxuan, SUN Xiaoqiong, WANG Hongwei Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 424-432.   DOI: 10.3969/j.issn.1000-1565.2022.04.013 Abstract （291）      PDF（pc） （1827KB）（252）       Knowledge map    Save The distribution and community structure changes of macrobenthic invertebrates in Baiyangdian Lake, two upstream reservoirs and four upstream rivers were investigated in different seasons in May, August and October in 2019. The dominant species were all pollution-resistant species in Baiyangdian Basin. The biomass mainly showed that the south was higher than the north in Baiyangdian Lake. The biodiversity of macrobenthic invertebrates showed that the central region was higher than the coastal region in Baiyangdian Lake. The changes of biomass and abundance in the two reservoirs were similar, which were higher in spring and autumn than in summer. Fuhe River, Xiaoyihe River and Jumahe River showed the lowest biomass in spring, while Shahe River had the highest biomass in spring. The biodiversity analysis of the four rivers showed that the biodiversity in spring was higher than that in other seasons. In a word, in terms of biomass and biodiversity, the upstream rivers and reservoirs mainly show significant differences in different seasons, while the differences between different regions are not significant.- DOI:10.3969/j.issn.1000-1565.2022.04.013白洋淀流域大型底栖无脊椎动物群落结构分析武志鑫,王玺,刘瑀璇,孙枭琼,王宏伟(河北大学 生命科学学院,生命科学与绿色发展研究院,河北 保定 071002)摘 要:2019年5月、8月和10月对白洋淀流域的淀区、2个上游水库和4条上游河流中大型底栖无脊椎动物的不同季节群落结构变化进行了调查,发现其优势物种均为耐污种.淀区群落结构主要表现出受区域性影响较大,受季节性影响不大的特点,分析其生物量和生物多样性指数,呈现出淀区南部生物量高于淀区北部,淀区中心生物多样性高于淀区边缘;2个水库生物量与丰度变化具有一定的相似性,均表现为春季和秋季高于夏季;府河、孝义河和拒马河表现为春季生物量最低,沙河春季生物量最高,在4条河流中春季生物多样性均高于夏、秋季.总之,从生物量和生物多样性两方面来看,上游河流和水库主要表现为不同季节间差异显著,而不同区域间差异不显著.关键词:白洋淀流域;大型底栖无脊椎动物;群落结构中图分类号:Q89 文献标志码:A 文章编号:1000-1565(2022)04-0424-09Analysis of community structure of macrobenthic invertebrates in Baiyangdian BasinWU Zhixin, WANG Xi, LIU Yuxuan, SUN Xiaoqiong, WANG Hongwei(Institute of Life Science and Green Development,School of Life Sciences, Hebei University, Baoding 071002, China )Abstract: The distribution and community structure changes of macrobenthic invertebrates in Baiyangdian Lake, two upstream reservoirs and four upstream rivers were investigated in different seasons in May, August and October in 2019. The dominant species were all pollution-resistant species in Baiyangdian Basin. The biomass mainly showed that the south was higher than the north in Baiyangdian Lake. The biodiversity of macrobenthic invertebrates showed that the central region was higher than the coastal region in Baiyangdian Lake. The changes of biomass and abundance in the two reservoirs were similar, which were higher in spring and autumn than in summer. Fuhe River, Xiaoyihe River and Jumahe River showed the lowest biomass in spring, while Shahe River had the highest biomass in spring. The biodiversity analysis of the four rivers showed that the biodiversity in spring was higher than that in other seasons. In a word, in terms of biomass and biodiversity, the upstream rivers and reservoirs mainly show significant differences in different seasons, while the differences between different regions are not significant.- 收稿日期:2021-11-02 基金项目: 中国水产科学研究院资助项目(2130135);教育部留学回国基金资助项目(201808130270); 河北省自然科学基金资助项目(C2019201390);河北省留学人员项目(2022);河北大学实验开放项目(sy202091) 第一作者:武志鑫(1994—),女,山东菏泽人,河北大学在读硕士研究生,主要从事水生生物研究.E-mail: wzx121207@163.com 通信作者:王宏伟(1970—),女,河北张家口人,河北大学教授,博士,主要从事水生生物环境监测与保护研究.E-mail: whw6688@126.com第4期武志鑫等:白洋淀流域大型底栖无脊椎动物群落结构分析 Reference | Related Articles | Metrics | Comments（0）

Select

Determination of trace bromophenols in water by precolumn derivatization-SPE-GC/MS GE Jiayu, LIANG Haiyan, LIU Dong, LI Chunling, ZHANG Fengquan, ZHAO Qian Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 395-402.   DOI: 10.3969/j.issn.1000-1565.2022.04.009 Abstract （252）      PDF（pc） （964KB）（250）       Knowledge map    Save In this work, bromophenols(BPs)in water samples were enriched by solid phase extraction, with acetic anhydride as derivative reagent and gas chromatography-mass spectrometer as detection instrument and an analysis method suitable for trace BPs in water was established. The method was evaluated by the standard recovery experiment of municipal water sample. After derivatization, BPs showed good chromatographic response signal. The detection limits were 0.8—17.7 ng/mL. The addition recoveries of blank water and municipal water ranged from 93.2% to 114.5%, 68.3% to 110.1%, and only the addition recoveries of 2,4,6-tribromophenol(2,4,6-TBP)was low, ranged from 68.3% to 73.0%. The relative standard deviations were less than 20%. This method was proved to have good sensitivity, recovery and repeatability, and can be applied for the determination of BPs in actual water samples. Reference | Related Articles | Metrics | Comments（0）

Select

Image denoising based on deep residual network with dual-domain information LI Kai, ZHANG Hui, CUI Lijuan, PENG Jinjia, CHEN Taixi Journal of Hebei University(Natural Science Edition)    2023, 43 (2): 216-224.   DOI: 10.3969/j.issn.1000-1565.2023.02.014 Abstract （209）      PDF（pc） （1255KB）（235）       Knowledge map    Save The denoising technology based on deep learning improves the image quality by considering visual artifacts and overall smoothing noise. However, they rarely involve the restoration of edge details. In this paper, a deep denoising network model based on dual-domain mapping and residual learning is proposed. The network learning information is extended by the fusion of wavelet domain information and spatial domain information. By introducing multi-scale learning and dilated convolution into the activation unit, the image features are extracted and the network parameters are reduced. In order to further improve the denoising results, the joint loss function of wavelet domain loss and spatial domain loss are combined to guide the network to obtain more edges and details. Experimental results show that the proposed method can not only effectively remove image noise, but also better restore image texture details, and obtain better results in both subjective and objective evaluation. Reference | Related Articles | Metrics | Comments（0）

Select

Recovery of potato strach during separation and characterization process using field-flow fractionation ZHANG Wenhui, SONG Tiange, SUN Yushan, SHEN Shigang, DOU Haiyang Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 376-383.   DOI: 10.3969/j.issn.1000-1565.2022.04.007 Abstract （256）      PDF（pc） （1376KB）（234）       Knowledge map    Save Potato starch was separated and characterized by field-flow fractionation. The interactions between the sample and the surface of ultrafiltration membrane in AF4 were investigated. The effects of ionic strength of carrier liquid, injection mass, cross-flow rate, and focusing time on the sample recovery were evaluated. The repeatability of the results was examined. The highest recovery of potato starch(97.30±0.02)% was obtained with a carrier liquid containing 5 mmol/L NaNO3 and 3 mmol/L NaN3, pH 7.00; injection mass, 15 μg; cross-flow rate, 1.0 mL/min; focusing time, 2.5 min. The method developed in this study showed good repeatability in terms of radius of gyration and molar mass with their relative standard deviations of 1.18% and 5.67%, respectively. Reference | Related Articles | Metrics | Comments（0）

Select

Progress on extraction, isolation and antitumor activity of seaweed polypeptides SHEN Jinyang,ZHANG Xuan,YU Yuanyuan,ZHANG Shicheng,SHI Liuqing,DONG Zibo Journal of Hebei University(Natural Science Edition)    2023, 43 (4): 379-386.   DOI: 10.3969/j.issn.1000-1565.2023.04.006 Abstract （229）      PDF（pc） （578KB）（224）       Knowledge map    Save Seaweed is an important marine life and an important source of food for people. Extensive previous studies have confirmed that seaweed contains a lot of protein. However, due to the low content of polypeptides, polypeptides are difficult to be extracted and purified by the traditional methods. At present, enzymatic hydrolysis and chemical extraction are more commonly used for extraction, and chromatography and membrane separation are used for purification. A higher purity polypeptides could be obtained from seaweed, and its structure was identified using MS-related technique. Seaweed polypeptides have a strong effect against tumor, and the mechanisms are manifested in many aspects. In this paper, the latest extraction, purification and identification methods of seaweed polypeptides, as well as the latest research progress of their anti-tumor activity were reviewed, so as to provide reference for their further development and utilization. Reference | Related Articles | Metrics | Comments（0）

Select

Classification of donkey meat and other meat based on nutrient compositions and principal component analysis NIU Xiaoying, MU Xiaoqing, SUN Jie, ZHANG Chunjiang,ZHAO Zhilei, TIAN Te Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 483-493.   DOI: 10.3969/j.issn.1000-1565.2022.05.006 Abstract （387）      PDF（pc） （1007KB）（223）       Knowledge map    Save Forty fresh donkey meat, and eight pork, eight beef and eight mutton samples were collected. Fat and protein in samples were determined by Soxhlet extraction and Kjeldahl method. Fatty acids were determined by gas chromatography, and amino acids were determined using an automatic amino acid analyzer with the method of cation exchange chromatography separation and ninhydrin post-column derivatization. One-way analysis of variance(ANOVA)was carried out, and fat, protein, tetradecanoic acid,- DOI:10.3969/j.issn.1000-1565.2022.05.006基于营养成分和主成分分析的驴肉与其他肉类分类研究牛晓颖1,牟晓晴1,孙杰1,2,张春江2,赵志磊1,田特1(1.河北大学 质量技术监督学院,河北 保定 071002;2.中国农业科学院 农产品加工研究所,农业农村部农产品加工综合性重点实验室,北京 100193)摘 要:选取生鲜驴肉样品40个,生鲜猪肉、牛肉、羊肉样品各8个,使用索氏抽提法和凯氏定氮法分别检测了样品的肌间脂肪和蛋白质含量,采用气相色谱法检测了样品的多种脂肪酸,并使用阳离子交换色谱分离、茚三酮柱后衍生法对样品的多种氨基酸含量进行了检测.对驴肉和其他肉类样品的多种营养成分含量进行了单因素方差分析. 结果发现:脂肪、蛋白质、肉豆蔻酸、十五碳酸、棕榈酸、棕榈油酸、硬脂酸、亚油酸、油酸及总不饱和脂肪酸、总饱和脂肪酸具有极显著差异,二十四碳一烯酸、反式油酸、苏氨酸、丝氨酸、异亮氨酸、亮氨酸、赖氨酸、组氨酸和脯氨酸具有显著差异,门冬氨酸、谷氨酸、甘氨酸、丙氨酸、酪氨酸、精氨酸和总氨基酸具有一定差异.对不同差异水平指标组合分别进行了主成分分析,发现有明显的聚类趋势,其中极显著差异指标数据(多为风味成分)能够完全将驴肉和其他肉类分开.研究结果表明:使用营养成分对驴肉和其他肉类进行分类是可行的,不同肉类所具有的不同风味特征是分类的关键.关键词:驴肉;分类;营养成分;方差分析;主成分分析中图分类号:TS251.7 文献标志码:A 文章编号:1000-1565(2022)05-0483-11Classification of donkey meat and other meat based on nutrient compositions and principal component analysisNIU Xiaoying1, MU Xiaoqing1, SUN Jie1,2, ZHANG Chunjiang2,ZHAO Zhilei1, TIAN Te1(1. College of Quality and Technical Supervision, Hebei University, Baoding 071002, China; 2. KeyLaboratory of Agro-Products Processing, Ministry of Agriculture and Rural Affairs, Institute of FoodScience and Technology, Chinese Academy of Agricultural Sciences(CAAS), Beijing 100193, China)Abstract: Forty fresh donkey meat, and eight pork, eight beef and eight mutton samples were collected. Fat and protein in samples were determined by Soxhlet extraction and Kjeldahl method. Fatty acids were determined by gas chromatography, and amino acids were determined using an automatic amino acid analyzer with the method of cation exchange chromatography separation and ninhydrin post-column derivatization. One-way analysis of variance(ANOVA)was carried out, and fat, protein, tetradecanoic acid,- 收稿日期:2022-05-14 基金项目:河北省重点研发计划项目(21327108D) 第一作者:牛晓颖(1980—),女,河北清河人,河北大学副教授,博士,主要从事农产品和食品无损检测技术方向研究.E-mail: xiaoyingniu@126.com 通信作者:赵志磊(1977—),男,河北辛集人,河北大学教授,博士,主要从事食品质量和安全检测方向研究.E-mail: zhaozhilei-3208@163.com第5期牛晓颖等:基于营养成分和主成分分析的驴肉与其他肉类分类研究pentadecanoic acid, palmitic acid, palmitoleic acid, stearic acid, linoleic acid, oleic acid, total unsaturated fatty acid and total saturated fatty acid in donkey meat and other meat samples show statistically highly significant differences. Tetracosaenoic acid, elaidic acid, threonine, serine acid, isoleucine, leucine, lysine, histidine acid and proline, show significant differences. Aspartic acid, glutamic acid, glycine, lacid,phenylalanine, tyrosine, l-arginine, and total amino acids show difference. Principal component analysis was performed on the combinations of nutrient compositions at different significance levels, and obvious clustering tendencies for donkey meat and other meats samples were found. Donkey meat samples can be correctly identified by the first two principal component scores extracted from the nutrient compositions of the highly significant differences(mostly flavor components). The results indicate that the classification of donkey meat and other meats based on the nutrient compositions combination is feasible, flavor component is a crucial classificant factor. Reference | Related Articles | Metrics | Comments（0）

Select

Advanced progress of constructed wetland technology for tail sewage treatment based on case analysis ZHAO Chunxia, LI Tianyi, FU Yijun, WANG Hongjie Journal of Hebei University(Natural Science Edition)    2023, 43 (1): 75-82.   DOI: 10.3969/j.issn.1000-1565.2023.01.011 Abstract （292）      PDF（pc） （1289KB）（221）       Knowledge map    Save The constructed wetland technology integrates the synergistic removal mechanism of pollutants in water by substrates, microorganisms and plants. It is widely used to improve the tail water quality of sewage plants as a green and low consumption ecological restoration technology. Some cases of tail water recycling for urban sewage plants are summarized based on constructed wetland technology through analyzing the operation modes and advantages and disadvantages of different constructed wetland processes. The design of composite constructed wetland process based on different water quality characteristics was proposed as a reference for the sewage recycling. Reference | Related Articles | Metrics | Comments（0）

Select

Optimization of preparation of peanut shell biochar by response surface methodology and its adsorption of Cr(Ⅵ)in water DENG Tiantian,LI Hansheng, MA Pei, XU Mengxing, YE Zixin, ZHAI Liping Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 384-394.   DOI: 10.3969/j.issn.1000-1565.2022.04.008 Abstract （241）      PDF（pc） （1777KB）（220）       Knowledge map    Save In order to explore the removal effect of biomass charcoal on heavy metal ions, a preparation conditions of the optimal biomass carbon were obtained by response surface optimization method well using peanut shell as raw material and ZnCl2 as modifier. In addition, the effects of different single factors on the adsorption of Cr(Ⅵ)in water by peanut shell biomass carbon were studied. The results showed that the optimum preparation conditions of peanut shell biochar were as follows: ZnCl2 modifier concentration as 4 mol/L, carbon burning temperature as 500 ℃, carbon burning time as 3 h. The single factor experiment showed that the optimum reaction condition was pH=2 and dosage=50 mg. At this time, the adsorption rate can reach to 93.72%, and the higher the temperature resulted the more conducive to adsorption. The isothermal adsorption experiment conforms to the Langmuir model, which showed that the adsorption process was dominated by monolayer adsorption, which belongs to endothermic reaction. The kinetics accorded with the quasi second order equation, indicating that the adsorption process was mainly chemisorption. Reference | Related Articles | Metrics | Comments（0）

Select

Prokaryotic expression,purification and biological activity identification of recombinant human leptin protein ZHOU Xiangyang, LI Zhongkai, HAO Tengfei, DING Guangshuo, ZHENG Wenhui, LI Wenjuan Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 511-518.   DOI: 10.3969/j.issn.1000-1565.2022.05.010 Abstract （289）      PDF（pc） （852KB）（219）       Knowledge map    Save To avoid the formation of inclusion bodies and the low yield caused by protein aggregation in the process of refolding in vitro, during the large-scale production of recombinant human leptin protein(hLeptin), the high-level soluble expression of hLeptin in Escherichia coli was investigated, and the biological activity was detected. The fusion expression plasmid pET-30a(+)-SUMO-Lep was constructed by using the coding sequence of mature peptide of hLeptin and pET-30a(+)-SUMO system, which was transformed into E.coli BL21(DE3)and was induced by isopropyl-β-D-thiogalactose(IPTG). Afterwards, the recombinant protein was purified by Ni metal affinity chromatography, and the mature hLeptin- DOI:10.3969/j.issn.1000-1565.2022.05.010重组人瘦素蛋白的原核表达、纯化和生物学活性鉴定周向阳1,2,李仲凯3,郝腾飞3,丁光硕4,郑文慧1,李文娟1,2(1.河北大学 基础医学院,河北 保定 071000;2.河北省炎性自身免疫性疾病发病机制及防治重点实验室,河北 保定 071000;3.河北农业大学 生命科学学院,河北 保定 071001;4.河北大学 公共卫生学院,河北 保定 071000)摘 要:为解决重组人瘦素蛋白(hLeptin)大规模生产过程中包涵体的形成以及体外重折叠过程中蛋白聚集导致的低产量,探究在大肠杆菌中hLeptin高水平可溶性的表达,并进行生物学活性检测.利用hLeptin成熟肽基因与pET-30a(+)-SUMO系统构建融合表达质粒pET-30a(+)-SUMO-Lep,转化至大肠杆菌BL21(DE3),加入异丙基-β-D-硫代半乳糖(IPTG)进行诱导表达,之后经Ni金属亲和层析纯化,并切去SUMO融合标签后获得成熟hLeptin.重组hLeptin表达量高,主要以可溶形式存在.通过KM小鼠减肥实验和CCK8实验证明重组hLeptin具有生物学活性.综上,使用SUMO融合标签,以增强hLeptin在大肠杆菌中的高效可溶性高纯度的表达,为大规模生产hLeptin提供了一种新方法,同时为表达可溶性重组蛋白研究提供了一定的基础.关键词:重组hLeptin;SUMO;原核表达;生物学活性中图分类号:Q78 文献标志码:A 文章编号:1000-1565(2022)05-0511-08Prokaryotic expression,purification and biological activity identification of recombinant human leptin proteinZHOU Xiangyang1,2, LI Zhongkai3, HAO Tengfei3, DING Guangshuo4, ZHENG Wenhui1, LI Wenjuan1,2(1.School of Basic Medicine Sciences, Hebei University, Baoding 071000, China;2.Key Laboratory of Pathogenesis Mechanism and Control of Inflammatory Autoimmune Diseases in Hebei Province, Baoding 071000, China;3.College of Life Sciences, Hebei Agricultural University, Baoding 071001, China;4.College of Public Health, Hebei University, Baoding 071000, China)Abstract: To avoid the formation of inclusion bodies and the low yield caused by protein aggregation in the process of refolding in vitro, during the large-scale production of recombinant human leptin protein(hLeptin), the high-level soluble expression of hLeptin in Escherichia coli was investigated, and the biological activity was detected. The fusion expression plasmid pET-30a(+)-SUMO-Lep was constructed by using the coding sequence of mature peptide of hLeptin and pET-30a(+)-SUMO system, which was transformed into E.coli BL21(DE3)and was induced by isopropyl-β-D-thiogalactose(IPTG). Afterwards, the recombinant protein was purified by Ni metal affinity chromatography, and the mature hLeptin- 收稿日期:2022-03-02 基金项目:河北省自然科学基金资助项目(H2019201084);河北大学医学学科培育项目(2021A01);河北大学大学生创新创业项目(2022309) 第一作者:周向阳(1997—),男,山西大同人,河北大学在读硕士研究生,主要从事肿瘤代谢及化学预防的研究.E-mail: zxy9708@163.com 通信作者:李文娟(1977—),女,甘肃静宁人,河北大学副教授,博士,主要从事肿瘤代谢研究.E-mail: liwenjuan@hbu.edu.cn第5期周向阳等:重组人瘦素蛋白的原核表达、纯化和生物学活性鉴定was obtained after cutting off the SUMO fusion tag. The recombinant hLeptin was highly expressed and mainly existed in soluble form. The biological activity was confirmed by KM mouse Weight-Losing Test and the CCK8 assay. In this study, we employed the SUMO fusion tag to increase the solubility and the purity of hLeptin expression in E. coli, which could provide a novel method for large-scale production of leptin and lay a foundation for the expression of soluble recombinant protein. Reference | Related Articles | Metrics | Comments（0）

Select

Effect of IAA on the growth and photosynthetic characteristics of Quercus sessilis at seedling stage SHI Haiyan, ZHANG Zhigang, LI Hong,YANG Jianjun, LI Bin, SHI Kaiqi, YANG Lu Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 519-529.   DOI: 10.3969/j.issn.1000-1565.2022.05.011 Abstract （310）      PDF（pc） （1148KB）（219）       Knowledge map    Save The phenomenon of topping out exists during the growth and development of young Quercus sessilis. In order to investigate the effect of spraying different mass concentrations of the exogenous plant growth regulator indole-3-acetic acid(IAA)on the growth and photosynthetic characteristics- DOI:10.3969/j.issn.1000-1565.2022.05.011IAA对幼苗期夏橡生长及光合特性的影响石海燕1,张志刚2,李宏2,杨建军1,李斌3,史开奇3,杨璐4,5(1.新疆大学 生态与环境学院,绿洲生态教育部重点实验室,新疆 乌鲁木齐 830017;2.新疆林科院 造林治沙研究所,新疆 乌鲁木齐 830000;3.伊犁州林木良种繁育试验中心,新疆 察布查尔 835311;4.新疆林果树种选育与栽培重点实验室,新疆 乌鲁木齐 830000;5.新疆林木资源与利用国家林草局重点实验室,新疆 乌鲁木齐 830000)摘 要:幼苗期夏橡在生长发育过程中存在封顶现象,为探究外源植物生长调节剂吲哚乙酸(indole-3-acetic acid,IAA)对封顶现象的破除作用,以1年生夏橡播种苗木为研究对象,在夏橡封顶时喷施不同质量浓度的IAA.通过对夏橡生长特性、光合特性的测定,运用最小显著性差异法(least significant difference,LSD)及沃勒-邓肯对比分析在喷施不同质量浓度IAA后幼苗期夏橡生长特性与叶片光合性能的差异,结果表明:喷施IAA提高了夏橡光合特性日变化指标Gs、Tr及Ci,进而提高了植株的净光合速率(Pn),低质量浓度IAA处理下幼苗期夏橡Pn下午峰值提前,高质量浓度处理后光合“午休”现象消失;IAA处理对于延缓Pn下降有一定作用,质量浓度为60 mg/L的IAA处理时Pn最大;IAA处理前期主要受气孔限制,后期以非气孔限制为主.得出结论:IAA的喷施会提高夏橡幼苗的Pn,延缓Pn的下降,此外IAA质量浓度为100~120 mg/L时,破除幼苗期夏橡封顶现象效果最显著.关键词:幼苗期夏橡;封顶现象;IAA;光合特性中图分类号:Q145.1 文献标志码:A 文章编号:1000-1565(2022)05-0519-11Effect of IAA on the growth and photosynthetic characteristics of Quercus sessilis at seedling stageSHI Haiyan1, ZHANG Zhigang2, LI Hong2,YANG Jianjun1, LI Bin3, SHI Kaiqi3, YANG Lu4,5(1.Key Laboratory of Oasis Ecology of Education Ministry, College of the Ecology and Environment, Xinjiang University, Urumqi 830017, China; 2.Institute of Afforestation and Sand Control, Xinjiang Academy of Forestry Sciences, Urumqi 830000, China; 3.Yill Trees Variety Breeding Center of Xinjiang Uygur Autonomous Region, Chabchal 835311, China; 4.Key Laboratory of Fruit Tree Species Breeding and Cultivation in Xinjiang, Urumqi 830000, China; 5.Key Laboratory of Forest Resources and Utilization in Xinjiang of National Forestry and Grassland Administration, Urumqi 830000, China)Abstract: The phenomenon of topping out exists during the growth and development of young Quercus sessilis. In order to investigate the effect of spraying different mass concentrations of the exogenous plant growth regulator indole-3-acetic acid(IAA)on the growth and photosynthetic characteristics- 收稿日期:2022-03-25 基金项目:伊犁州林木良种繁育试验中心国家杨树、白榆重点林木良种基地补助项目(202110);新疆林草科技专项(XJLCKJ2022008) 第一作者:石海燕(1998—),女,河北邢台人,新疆大学在读硕士研究生,主要从事生态修复与可持续发展研究. E-mail: shihaiyan_ecology@163.com 通信作者:杨建军(1978—),男,新疆乌苏人,新疆大学副教授,博士,主要从事干旱区水土保持与荒漠化防治研究. E-mail: yjj@xju.edu.cn第5期石海燕等:IAA对幼苗期夏橡生长及光合特性的影响of Q. sessilis, this paper used 1-year-old Q. sessilis sown seedlings as the research object, and IAA sprayed at different mass concentrations when the Q. sessilis were topped out. By measuring the growth characteristics and photosynthetic characteristics of Q. sessilis, the differences in growth characteristics and photosynthetic performance of Q. sessilis leaves at the seedling stage after spraying different concentrations of IAA were compared and analyzed using least significant difference(LSD)and Waller-Duncan comparisons. The results showed that the daily changes of Gs、Tr and Ci in photosynthetic characteristics of Q. sessilis were increased by IAA spraying, which in turn increased the photosynthetic rate(Pn )of the plants, and the afternoon peak of Pn in Q. sessilis at the seedling stage was advanced under the low mass concentration of IAA treatment, and the photosynthetic “lunch break” phenomenon disappeared after the high mass concentration treatment. Which had a certain effect on delaying the decrease of. Pn was maximum at the IAA treatment with a mass concentration of 60 mg/L. The IAA treatment was mainly stomatal-limited in the early stages and non-stomatal-limited in the later stages. It was concluded that the application of IAA increased the Pn of Q. sessilis seedlings and delayed the decrease of Pn. In addition, IAA at a mass concentration of 100~120 mg/L was the most effective in breaking the Q. sessilis topping phenomenon at the seedling stage. Reference | Related Articles | Metrics | Comments（0）

Select

UFMC channel estimation algorithm based on improved LMMSE LIU Zichang, HAO Yulian, ZHANG Suoliang Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 433-437.   DOI: 10.3969/j.issn.1000-1565.2022.04.014 Abstract （273）      PDF（pc） （663KB）（217）       Knowledge map    Save Aiming at the deficiency that the prior channel correlation matrix information is required when the linear minimum mean square error(LMMSE)algorithm is directly applied to the universal filtered multi-carrier(UFMC)system, an improved algorithm based on LMMSE is proposed in this thesis. The algorithm smooths the channel frequency response obtained by the least square(LS)algorithm in the frequency domain, determines the ideal channel sampling length by optimizing the truncation of sampling points in the time domain, the optimal channel correlation matrix is obtained by iterative estimation method to avoid prior channel correlation matrix information. The MATLAB simulation verifies that the improved algorithm can effectively suppress the interference of noise. Compared with the traditional LMMSE algorithm, the bit error performance can be improved by about 2 dB, which can effectively improve the accuracy of channel estimation. Reference | Related Articles | Metrics | Comments（0）

Select

Parameter estimation of time censored exponential life data under ranked set sampling DONG Xiaofang, GAO Yang, ZHANG Liangyong Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 337-342.   DOI: 10.3969/j.issn.1000-1565.2022.04.001 Abstract （345）      PDF（pc） （345KB）（212）       Knowledge map    Save In order to solve the problem of parameter estimation for time censored exponential life data, the maximum likelihood estimation using ranked set sampling method is studied. For the problem that likelihood equation’s root under ranked set sampling is not found, some terms of likelihood equation are replaced with their expectations, and the modified maximum likelihood estimation is given. The comparison results of estimation efficiencies show that the proposed estimator using ranked set sampling method is better than maximum likelihood estimator using simple random sampling method. Reference | Related Articles | Metrics | Comments（0）

Select

Angular spectrum algorithm for Fresnel diffraction integral HAN Jiacheng, GUO Wenya, ZHAO Yanan, YANG Lijun, WANG Ying, ZHANG Suheng Journal of Hebei University(Natural Science Edition)    2023, 43 (3): 237-247.   DOI: 10.3969/j.issn.1000-1565.2023.03.003 Abstract （276）      PDF（pc） （1023KB）（211）       Knowledge map    Save Fresnel diffraction can be regarded as a linear space-invariant system, so the Fresnel diffraction integral can be calculated numerically in the spectral domain using the angular spectrum. First, the implementation of the angular spectrum algorithm is explained in detail, including the ideal sampling conditions, the origins and influence range of the wraparound error, and the selection of the calculation window size. Then the Fresnel diffraction field of a Gaussian beam illuminated cosine grating is numerically calculated using the angular spectrum algorithm. A comparison between the numerical solution and the analytical solution shows that the angular spectrum algorithm can achieve very high accuracy when the ideal sampling conditions are met and the calculation window size is correctly selected. Finally, a single-lens coherent imaging is numerically simulated to further demonstrate the implementation of the angular spectrum algorithm. Reference | Related Articles | Metrics | Comments（0）

Select

One new record species of the genus Triplax (Coleoptera: Erotylidae)from China YAN Zihan, HOU Jialin, ZANG Haoming, WANG Haishan, LI Jing Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 501-503.   DOI: 10.3969/j.issn.1000-1565.2022.05.008 Abstract （272）      PDF（pc） （452KB）（209）       Knowledge map    Save One species, Triplax amoena Solsky,1871 of the family Erotylidae is reported from China for the first time. The description and illustration are given. All studied specimens are deposited in the Biological Control Laboratory, College of Plant Protection, Hebei Agricultural University. Reference | Related Articles | Metrics | Comments（0）

Select

Cloning and expression of Actinokineospora alba DSM 45114T rpf gene and structure prediction of Rpf protein ZHANG Yufan, LIU Jingjing, CAO Min, LIU Tongtong, CHEN Xue, ZHANG Xiumin Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 411-420.   DOI: 10.3969/j.issn.1000-1565.2022.04.011 Abstract （281）      PDF（pc） （1684KB）（196）       Knowledge map    Save Resuscitation-promoting factor(Rpf)is widely present in gram-positive bacteria with high G+C content and is related to the resuscitation of dormant cells. There are some differences in the types and quantities of Rpf among different bacteria. In order to understand the difference of rpf genes in different species, bioinformatics analysis was conducted on the amino acid sequence, hydrophobicity, signal peptide, phosphorylation site, tertiary structure and structural functional domain of three Rpf proteins in Actinokineospora alba DSM 45114T. The specific primers for the three rpf genes of A. alba- DOI:10.3969/j.issn.1000-1565.2022.04.011白色放线动孢菌 DSM 45114T rpf基因的克隆表达及结构预测张宇帆,刘菁菁,曹敏,刘彤彤,陈雪,张秀敏(河北大学 生命科学学院,生命科学与绿色发展研究院,河北省微生物育种与保育工程实验室, 河北省微生物多样性研究与应用重点实验室, 河北 保定 071002)摘 要:复苏促进因子(Rpf)广泛存在于高 G+C 含量的革兰氏阳性细菌中,与休眠细胞的复苏有关,且不同细菌Rpf的种类和数量有一定差异.为了解不同物种中rpf基因的差别,对白色放线动孢菌(Actinokineospora alba)DSM 45114T的3个Rpf蛋白的氨基酸序列、疏水性、信号肽、磷酸化位点、三级结构以及结构功能域进行生物信息学预测分析.设计了白色放线动孢菌(A. alba)DSM 45114T rpf基因的特异性引物,从其基因组中扩增出了3个不同的rpf基因,随后构建pET-28a(+)-rpf表达载体,在Escherichia coli BL21(DE3)中进行诱导表达,成功表达了Rpf-2蛋白.将重组Rpf-2蛋白加入到活的非可培养(viable but non culturable,VBNC)状态的藤黄微球菌(Micrococcus luteus)和滨海红球菌(Rhodococcus marinonascens)中,结果表明,重组Rpf-2蛋白可以促进其复苏,添加量在体积分数为10%时复苏效果最好.本研究为后续探讨白色放线动孢菌(A. alba)Rpf蛋白的功能奠定了基础.关键词:白色放线动孢菌;复苏促进因子;异源表达;结构预测中图分类号:Q93 文献标志码:A 文章编号:1000-1565(2022)04-0411-10Cloning and expression of Actinokineospora alba DSM 45114T rpf gene and structure prediction of Rpf proteinZHANG Yufan, LIU Jingjing, CAO Min, LIU Tongtong, CHEN Xue, ZHANG Xiumin(Key Laboratory of Microbial Diversity Research and Application of Hebei Province, Engineering Laboratory of Microbial Breeding and Preservation of Hebei Province,Institute of Life Science and Green Development, School of Life Sciences, Hebei University, Baoding 071002, China)Abstract: Resuscitation-promoting factor(Rpf)is widely present in gram-positive bacteria with high G+C content and is related to the resuscitation of dormant cells. There are some differences in the types and quantities of Rpf among different bacteria. In order to understand the difference of rpf genes in different species, bioinformatics analysis was conducted on the amino acid sequence, hydrophobicity, signal peptide, phosphorylation site, tertiary structure and structural functional domain of three Rpf proteins in Actinokineospora alba DSM 45114T. The specific primers for the three rpf genes of A. alba- 收稿日期:2022-01-03 基金项目:河北省重点研发计划项目(20326614D);河北省自然科学基金资助项目(C2020201005);河北大学2021年度研究生创新资助项目(HBU2021ss051) 第一作者:张宇帆(1997—),女,山西临汾人,河北大学在读硕士研究生,主要从事放线菌资源挖掘研究.E-mail:627256284@qq.com 通信作者:张秀敏(1970—),女,河北涞水人,河北大学教授,博士,主要从事微生物多样性及资源开发研究.E-mail:zhxiumin1106@126.com第4期张宇帆等:白色放线动孢菌 DSM 45114T rpf基因的克隆表达及结构预测DSM 45114T were designed, and corresponding genes were amplified. Subsequently, pET-28a(+)-rpf expression vectors were constructed and induced in Escherichia coli BL21(DE3), Rpf-2 protein was successfully expressed. Adding the recombinant Rpf-2 protein to the cells in viable but non culturable(VBNC)state of Micrococcus luteus and Rhodococcus marinonascens, the result showed that it could significantly promote their resuscitation, and the resuscitation effect was the most significant when 10% Rpf-2 protein was added. This laid a foundation for the subsequent study on the function of Rpf-2 protein in A. alba. Reference | Related Articles | Metrics | Comments（0）

Select

Object detection and classification of polyps based on improved Faster R-CNN YANG Kun, YUAN Jiacheng, GAO Cong, SUN Yufeng, LU Yufei,CHANG Shilong, XUE Linyan Journal of Hebei University(Natural Science Edition)    2023, 43 (1): 103-112.   DOI: 10.3969/j.issn.1000-1565.2023.01.015 Abstract （325）      PDF（pc） （1255KB）（193）       Knowledge map    Save In order to solve the problem of difficult classification of adenomatous polyps and hyperplastic polyps under colorectoscopy, an object detection and polyp classification model based on improved Faster R-CNN was proposed. Polyp images(1582 adenomatous polyp images, 844 hyperplastic polyp images)were image-enhanced in two ways, and 602 images(386 adenomatous images, 216 hyperplastic- DOI:10.3969/j.issn.1000-1565.2023.01.015基于改进的Faster R-CNN的息肉目标检测和分类方法杨昆1,2,3,原嘉成1,高聪4,孙宇锋1,路宇飞1,常世龙1,薛林雁1,2,3(1.河北大学 质量技术监督学院,河北 保定 071002;2.计量仪器与系统国家地方联合工程研究中心,河北 保定 071002;3.河北省新能源汽车动力系统轻量化技术创新中心, 河北 保定 071002;4.河北远东通信系统工程有限公司,河北 石家庄 050200)摘 要:为了解决结肠镜下腺瘤性息肉和增生性息肉不易分型的问题,提出一种基于改进的Faster R-CNN的目标检测及息肉分类模型.在数据预处理阶段,对原有的2 426张息肉图像(1 582张腺瘤性息肉图像,844张增生性息肉图像)通过2种方式进行图像增强,并且通过改进的特征提取、边界框回归以及非极大值抑制的网络,用602张图像(386张腺瘤性图像,216张增生性息肉图像)进行测试.通过实验证明,在交并比(IoU)取0.5时,获得了86.8%的平均精度均值,相较于改进之前提升了2.3%.实验结果验证了该模型的潜在临床应用价值.关键词:息肉;目标检测;分类;Faster R-CNN中图分类号:TP192.7 文献标志码:A 文章编号:1000-1565(2023)01-0103-10Object detection and classification of polyps based onimproved Faster R-CNNYANG Kun1,2,3, YUAN Jiacheng1, GAO Cong4, SUN Yufeng1, LU Yufei1,CHANG Shilong1, XUE Linyan1,2,3(1.College of Quality and Technical Supervision, Hebei University, Baoding 071002, China; 2. National & Local Joint Engineering Research Center of Metrology Instrument and System, Baoding 071002, China; 3.New Energy Vehicle Power System Lightweight Technology Innovation Center of Hebei Province, Baoding 071002, China; 4.Hebei Far East Communication System Engineering Co., Ltd, Shijiazhuang 050200, China)Abstract: In order to solve the problem of difficult classification of adenomatous polyps and hyperplastic polyps under colorectoscopy, an object detection and polyp classification model based on improved Faster R-CNN was proposed. Polyp images(1582 adenomatous polyp images, 844 hyperplastic polyp images)were image-enhanced in two ways, and 602 images(386 adenomatous images, 216 hyperplastic- 收稿日期:2022-02-12 基金项目:河北省自然科学基金资助项目(A2011201155);河北大学校长科研基金资助项目(XZJJ201914);河北大学多学科交叉研究项目(DXK201914) 第一作者:杨昆(1976—),男,河北保定人,河北大学教授,博士生导师,博士,主要从事生物医学图像处理方向研究.E-mail:yangkun@hbu.edu.cn 通信作者:薛林雁(1981—),女,河北广平人,河北大学副教授,博士,主要从事生物医学图像处理方向研究.E-mail:lyxue@hbu.edu.cn第1期杨昆等:基于改进的Faster R-CNN的息肉目标检测和分类方法polyp images)were tested. It is proved by experiments that when the intersection-union ratio(IoU)is set to be 0.5, an average precision of 86.8% is obtained, which is 2.3% higher than that before the improvement. The experimental results verified the potential clinical application value of this model. Reference | Related Articles | Metrics | Comments（0）

Select

Mechanism of Stellera chamaejasme L. in the treatment of reumatoid arthritis based on network pharmacology and animal experiment Huyiligeqi,BAI Xiaohong, BAI Meirong, BAO Wenshuang, Huhezhula, Laxinamujila Journal of Hebei University(Natural Science Edition)    2023, 43 (1): 48-57.   DOI: 10.3969/j.issn.1000-1565.2023.01.008 Abstract （228）      PDF（pc） （2988KB）（186）       Knowledge map    Save This work aims to predict and verify the potential mechanism of Stellera chamaejasme L. in the treatment of rheumatoid arthritis(RA)based on network pharmacology. The main chemical components of Stellera chamaejasme L. were obtained from TCMSP, PubMed and TCMID databases and literature mining. The therapeutic targets of Stellera chamaejasme L. were obtained by using Uniprot and- DOI:10.3969/j.issn.1000-1565.2023.01.008基于网络药理学及动物实验探讨瑞香狼毒治疗RA作用机制胡伊力格其1,2,白小红1,白梅荣1,2,包文双1,胡和珠拉1,2,拉喜那木吉拉1(1.内蒙古民族大学 蒙医药学院,内蒙古 通辽 028000;2.内蒙古民族大学 蒙医药研发工程教育部重点实验室,内蒙古 通辽 028000)摘 要:为探讨瑞香狼毒(Stellera chamaejasme L.)治疗类风湿性关节炎(rheumatoid arthritis,RA)的潜在机制,利用TCMSP、PubMed及TCMID数据库和文献挖掘获得瑞香狼毒主要化学成分,利用Swiss Target Prediction、Uniprot数据库获得瑞香狼毒治疗疾病靶点,运用OMIM、GeneCards及PharmGKB数据库获取RA主要作用靶点,通过对化学成分靶点与疾病基因进行交集整合,筛选瑞香狼毒治疗RA的潜在治疗靶点.使用Cytoscape 3.6.1 软件构建“药物-活性成分-靶点-疾病”相互作用网络图,将潜在治疗靶点用DAVID软件分析预测相关的生物学过程,并通过动物实验对主要生物学过程进行验证.采用ELISA检测瑞香狼毒对RA模型大鼠血清炎症因子的影响,该研究共筛选出瑞香狼毒60个活性成分,5 017个与RA潜在治疗靶点及380个交集靶点;动物实验结果表明,瑞香狼毒可以通过抑制炎症因子肿瘤坏死因子(TNF-α)、白介素-6(IL-6)、白介素-1β(IL-1β)表达以发挥抗RA作用.该研究揭示了网络药理学预测并指导实验设计的合理性,证实瑞香狼毒可以通过抑制炎症因子以发挥抗RA作用,为瑞香狼毒治疗RA的机制研究提供依据.关键词:网络药理学;瑞香狼毒;类风湿性关节炎;肿瘤坏死因子;白介素-6;白介素-1β中图分类号:R593.21 文献标志码:A 文章编号:1000-1565(2023)01-0048-10Mechanism of Stellera chamaejasme L. in the treatment of reumatoid arthritis based on network pharmacology and animal experiment Huyiligeqi1,2,BAI Xiaohong1, BAI Meirong1,2, BAO Wenshuang1, Huhezhula1,2, Laxinamujila1(1.School of Mongolian Medicine, Inner Mongolia Minzu University, Tongliao 028000,China;2.Key Laboratory of Mongolian Medicine Research and Development Engineering of the Ministry of Education, Inner Mongolia Minzu University, Tongliao 028000,China)Abstract: This work aims to predict and verify the potential mechanism of Stellera chamaejasme L. in the treatment of rheumatoid arthritis(RA)based on network pharmacology. The main chemical components of Stellera chamaejasme L. were obtained from TCMSP, PubMed and TCMID databases and literature mining. The therapeutic targets of Stellera chamaejasme L. were obtained by using Uniprot and- 收稿日期:2022-06-20 基金项目:内蒙古自治区自然科学基金资助项目(2018LH08063);内蒙古民族大学中药学(蒙药学)重点学科建设项目(ZYX005);内蒙古民族大学博士科研启动基金资助项目(2017B5408);内蒙古自治区高等学校蒙药安全评价“创新团队”项目(NMGIRT2216);内蒙古自治区自然科学基金资助项目(2020LH08013);蒙药标准化研究国际合作科技创新项目(MDKBZH2018033);蒙医药研发工程教育部重点实验室开发基金项目(MDK2021051);内蒙古自治区卫生健康科技计划项目(202202258) 第一作者:胡伊力格其(1978—),女,蒙古族,内蒙古通辽人,内蒙古民族大学副教授,博士,主要从事蒙药及复方质量标准和药学方面研究.E-mail:b13948550593@163.com第1期胡伊力格其等:基于网络药理学及动物实验探讨瑞香狼毒治疗RA作用机制Swiss Target Prediction databases. Main targets of RA were screened through GeneCards, OMIM and PharmGKB databases. The chemical component targets and disease targets were integrated to screen the potential therapeutic targets of Stellera chamaejasme L. for RA. Cytoscape 3.6.1 software was used to construct the “drug-component-target-disease” interaction network diagram. Meanwhile, potential therapeutic targets were analyzed by DAVID software to predict the relevant biological process. Finally, the main biological processes were verified by animal experiments. The effects of Stellera chamaejasme L. on serum inflammatory factors in RA model rats were detected by ELISA. A total of 60 active components of Stellera chamaejasme L., 5017 potential therapeutic targets and 380 common targets for RA were screened out. The results of animal experiments showed that Stellera chamaejasme L. attenuates RA by inhibiting the expression of inflammatory factors including tumor necrosis factor-α(TNF-α), interleukin-1β(IL-1β)and interleukin-6(IL-6). This study revealed the rationality of network pharmacology to predict and guide the experimental design and confirmed that Stellera chamaejasme L. exerted anti-RA effect by inhibiting inflammatory factors, and provided basis for the study of the mechanism of Stellera chamaejasme in treating RA. Reference | Related Articles | Metrics | Comments（0）

Select

Uncertain linguistic generalized weighted Heronian mean operator and its application in decision making HU Ximei, YANG Shuxia, TIAN Dazeng Journal of Hebei University(Natural Science Edition)    2023, 43 (2): 113-120.   DOI: 10.3969/j.issn.1000-1565.2023.02.001 Abstract （221）      PDF（pc） （851KB）（186）       Knowledge map    Save In practical multiple-attribute decision making problems, sometimes there are correlations between attributes, and attribute values are given in the form of uncertain language. In order to solve the multiple-attribute decision making problems with correlations between attributes in uncertain linguistic environment, the uncertain linguistic generalized weighted Heronian mean(ULGWHM)operator is given, and its properties are studied, including idempotency, boundedness, monotonicity, permutation and limit properties. Then a multiple-attribute decision making method based on this operator is presented. Finally, the feasibility of multiple-attribute decision making method based on ULGWHM operator is illustrated by an example. Reference | Related Articles | Metrics | Comments（0）

Select

Application and mechanism of photodynamic therapy in the treatment of diabetic foot ZHAO Jianxi, PANG Jingwen, TIAN Xiang, YAN Xinghan, ZHANG Zhiming, ZHAO Zhanjuan Journal of Hebei University(Natural Science Edition)    2023, 43 (2): 188-196.   DOI: 10.3969/j.issn.1000-1565.2023.02.011 Abstract （295）      PDF（pc） （609KB）（181）       Knowledge map    Save Diabetic foot is a foot tissue destruction unrelated to other traumatic factors and caused by diabetes, and is clinically chronic wound, often complicated by ischemia, peripheral neuropathy and infection; impaired healing increases the likelihood of infection, so anti-infective therapy is a key to the treatment of diabetic foot. At present, antibiotics are mostly used for anti-infection treatment in clinical practice, but the pathophysiological changes of diabetic foot hinder the penetration of antibiotics in ulcers, which cause difficulty in reaching the lesion site, and at the same time, antibiotic multidrug resistance also increases the difficulty of treatment of diabetic foot. Photodynamic therapy provides new options for the treatment of diabetic foot with its advantages of good targeting, low side effects, and no resistance to microorganisms. In recent years, photodynamic therapy has made good progress in the treatment of diabetic foot. Therefore, this article elaborates the application, therapeutic mechanism- DOI:10.3969/j.issn.1000-1565.2023.02.011光动力疗法在糖尿病足治疗中的应用及机制赵建喜1,庞静文2,田翔2,闫星寒3,张秩铭3, 赵占娟3(1.河北大学附属医院 放射科,河北 保定 071002; 2.河北大学 临床医学院,河北 保定 071002; 3.河北大学 基础医学院,河北 保定 071002)摘 要:糖尿病足是糖尿病导致的与其他外伤因素等无关的足部组织破坏,在临床上属于慢性伤口,常合并缺血、周围神经病变以及感染,其愈合受损增加了感染的可能,因此在糖尿病足的治疗过程中,抗感染治疗是关键.目前临床上多使用抗生素进行抗感染治疗,但糖尿病足的病理生理变化阻碍了抗生素在溃疡中的渗透,使其难以到达病变部位,同时,由于抗生素多重耐药现象逐渐严峻,也增加了糖尿病足的治疗难度.光动力疗法以其靶向性好、副作用低、对微生物无耐药性等优点给糖尿病足的医治提供了新的选择.近年来,光动力疗法在治疗糖尿病足方面取得了不错的进展.因此,本文对光动力疗法在糖尿病足中的应用、治疗机制、近期的研究成果等方面进行阐述.关键词:光动力疗法;糖尿病足;光敏剂;抗生素耐药中图分类号:Q81;R4 文献标志码:A 文章编号:1000-1565(2023)02-0188-09Application and mechanism of photodynamic therapy in the treatment of diabetic footZHAO Jianxi1, PANG Jingwen2, TIAN Xiang2, YAN Xinghan3, ZHANG Zhiming3, ZHAO Zhanjuan3(1. Department of Radiology, Affiliated Hospital of Hebei University, Baoding 071002,China; 2.School of Clinical Medicine, Hebei University, Baoding 071002,China; 3.School of Basic Medicine, Hebei University, Baoding 071002,China)Abstract: Diabetic foot is a foot tissue destruction unrelated to other traumatic factors and caused by diabetes, and is clinically chronic wound, often complicated by ischemia, peripheral neuropathy and infection; impaired healing increases the likelihood of infection, so anti-infective therapy is a key to the treatment of diabetic foot. At present, antibiotics are mostly used for anti-infection treatment in clinical practice, but the pathophysiological changes of diabetic foot hinder the penetration of antibiotics in ulcers, which cause difficulty in reaching the lesion site, and at the same time, antibiotic multidrug resistance also increases the difficulty of treatment of diabetic foot. Photodynamic therapy provides new options for the treatment of diabetic foot with its advantages of good targeting, low side effects, and no resistance to microorganisms. In recent years, photodynamic therapy has made good progress in the treatment of diabetic foot. Therefore, this article elaborates the application, therapeutic mechanism- 收稿日期:2022-06-07 基金项目:河北省自然科学基金资助项目(B2022201097);河北省医学科学研究课题计划项目(20220034);大学生创新创业训练计划项目(2022376);保定市科技计划项目(2172P002) 第一作者:赵建喜(1966—),男,河北保定人,河北大学附属医院主任医师,主要从事放射医学研究. E-mail:jianxizhaov@163.com 通信作者:赵占娟(1974—),女,河北保定人,河北大学副教授,博士,主要从事激光医学研究. E-mail:zhaozhanjuanv@163.com第2期赵建喜等:光动力疗法在糖尿病足治疗中的应用及机制河北大学学报(自然科学版) 第43卷and research results and so on in the treatment of photodynamic therapy in diabetic foot. Reference | Related Articles | Metrics | Comments（0）

Select

A network intrusion detection method based on SSA-BRF WEI Mingjun, ZHANG Xinnan, LIU Yazhi, ZHOU Taiyu Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 552-560.   DOI: 10.3969/j.issn.1000-1565.2022.05.014 Abstract （261）      PDF（pc） （916KB）（175）       Knowledge map    Save In order to solve the problem that the selection of hyper-parameters of random forest(RF)will have a great impact on the classification results of RF, an optimization method of RF hyper-parameters based on sparrow search algorithm(SSA)is proposed to help RF find a set of excellent hyper-parameters. Balanced random forest(BRF)is used to solve the problem that RF is difficult to accurately identify minority data, so as to improve the recall rate of the model for minority data. Finally, SSA-BRF model is constructed by integrating SSA and BRF, and the classification effect of the model is verified in CIC-IDS-2017 data set. Experimental results show that compared with RF, the accuracy, macro recall and macro F1 score of SSA-BRF are improved by 9.57%, 26.62% and 0.17 respectively. This model can improve the performance of network intrusion detection system to a certain extent. Reference | Related Articles | Metrics | Comments（0）

Select

Improved TDOA 3d positioning algorithm based on adaptive Levy flight WEI Zihui, LI Xiaoyang, WANG Le, CAI Daxin, YE Xingyue, DING Zhenjun Journal of Hebei University(Natural Science Edition)    2023, 43 (2): 207-215.   DOI: 10.3969/j.issn.1000-1565.2023.02.013 Abstract （237）      PDF（pc） （1222KB）（163）       Knowledge map    Save Aiming at the problem that existing algorithms in the time difference of arrival(TDOA)measurement scheme show unbalanced search ability, leading to low positioning accuracy and even failure in solution in the part of the three-dimensional positioning area, a new approach based on improved approach is proposed. The TDOA positioning algorithm based on pathfinder algorithm(PFA)enhances the individual's adaptability to the complex environment of the positioning area by integrating the adaptive Levy flight and the improved PFA algorithm, and solves the problems of premature algorithm and easy localization, thus improving the comprehensive performance of the algorithm. Through simulation and experiments, the results show that compared with Taylor algorithm and LM algorithm, the algorithm proposed in this paper(Levy-pathfinder algorithm, LPFA)can improve the positioning accuracy; compared with PSO algorithm and PFA algorithm, LPFA algorithm can improve the operation speed and obtain more accurate positioning results. Reference | Related Articles | Metrics | Comments（0）

Select

Performance assessment and parameter optimization of an internal model PI controller in frequency and time domains LI Shizhe, LIU Chang Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 530-541.   DOI: 10.3969/j.issn.1000-1565.2022.05.012 Abstract （321）      PDF（pc） （1058KB）（157）       Knowledge map    Save Because the performance degradation of the control system is usually related to the unreasonable parameters of the PI controller, and the single performance assessment index in time domain is not accurate, therefore a performance assessment method based on the combination of frequency domain and time domain is presented for the control object with pure delay characteristic,which overcomes the inaccuracy of a single performance metric. Under different control strategies and parameters, the distance between the system performance index and the reference curve or reference point is analyzed. For two typical high-order processes, different reduced-order models are given, and the model with the best fitting characteristics is applied to the design of internal model PI controller. Based on the results of frequency-domain and time-domain assessment, a method of re-optimizing and tuning the parameters of PI controller is presented, which is used to improve the performance of the control system,and it is realized by re-setting the parameters through the data-driven method. The structure is simple, and the operation efficiency is improved.- DOI:10.3969/j.issn.1000-1565.2022.05.012基于频域和时域的内模PI控制器性能评价与参数优化李士哲,刘畅(华北电力大学 控制与计算机工程学院,河北 保定 071003)摘 要:由于控制系统的性能降低通常与比例积分(proportion integration,简称PI)控制器不合理的参数有关,而且单一的时域性能评价指标不准确,因此,针对具有纯迟延特性的控制对象,给出了基于频域和时域相结合的性能评价方法,克服了单一性能指标的不准确性.在不同控制策略和参数下,分析了系统性能指标与基准曲线或基准点的距离.针对2个典型的高阶被控过程,分别给出了不同的降阶模型,并把拟合对象特性最好的模型用于内模PI控制器的设计.基于频域和时域评价的结果,给出了PI控制器参数重新优化和整定的方法,用于改善控制系统的性能,该方法通过数据驱动方法对参数进行重新整定来实现,提高了运算效率.仿真实验验证了上述性能评价和参数优化方法的有效性.关键词:性能评价;PI控制器;频域指标;时域指标;参数优化中图分类号:TP273 文献标志码:A 文章编号:1000-1565(2022)05-0530-12Performance assessment and parameter optimization of an internal model PI controller in frequency and time domainsLI Shizhe, LIU Chang(School of Control and Computer Engineering, North China Electric Power University, Baoding 071003, China)Abstract: Because the performance degradation of the control system is usually related to the unreasonable parameters of the PI controller, and the single performance assessment index in time domain is not accurate, therefore a performance assessment method based on the combination of frequency domain and time domain is presented for the control object with pure delay characteristic,which overcomes the inaccuracy of a single performance metric. Under different control strategies and parameters, the distance between the system performance index and the reference curve or reference point is analyzed. For two typical high-order processes, different reduced-order models are given, and the model with the best fitting characteristics is applied to the design of internal model PI controller. Based on the results of frequency-domain and time-domain assessment, a method of re-optimizing and tuning the parameters of PI controller is presented, which is used to improve the performance of the control system,and it is realized by re-setting the parameters through the data-driven method. The structure is simple, and the operation efficiency is improved.- 收稿日期:2022-02-18 基金项目:深圳市可持续发展科技专项项目(KCXFZ20201221173402007 ) 第一作者:李士哲(1981—),男,河北保定人,华北电力大学(保定)讲师,博士,主要从事控制系统性能评价方向研究.E-mail:lishizhe121@163.com 通信作者:刘畅(1999—),女,河北保定人,华北电力大学(保定)在读硕士研究生,主要从事控制系统性能评价及故障诊断方向研究.E-mail:1432497470@qq.com第5期李士哲等:基于频域和时域的内模PI控制器性能评价与参数优化The simulation results verify the effectiveness of the above methods. Reference | Related Articles | Metrics | Comments（0）

Select

Effects of oleanolic acid on the expression of key genes of insulin/IGF1 pathway in leydig cells of aging rats LI Shaohua, NIU Shuang, DONG Ziyi,SONG Yicheng, NIU Siyun Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 403-410.   DOI: 10.3969/j.issn.1000-1565.2022.04.010 Abstract （285）      PDF（pc） （1280KB）（155）       Knowledge map    Save To investigate the effect of oleanolic acid on leydig cells of aging rats, the MTT method was used to determine the optimal drug concentration of oleanolic acid. The aging module of rat leydig cell was built according to the free radical oxidative damage method. Gene and protein expression of the key gene in the insulin/insulin-like growth factor 1(IGF1)signaling pathway was detected by RT-qPCR, immunofluorescence technique(IF), and Western blot. After treated with INSR inhibitor, cell apoptosis was performed by flow cytometry. The results showed that INSR, IRS1, IRS2 and IGF1 mRNA transcription level and protein expression level were significantly downregulated(P<0.05); IGFBP3 mRNA transcription level was significantly upregulated(P<0.05), otherwise, the expression could not be detected by IF and Western blot. Oleanolic acid reversed the above phenomenon, compared to aging group(P<0.05).- DOI:10.3969/j.issn.1000-1565.2022.04.010齐墩果酸对衰老大鼠睾丸间质细胞胰岛素/IGF1通路关键基因表达的影响李少华1,2,牛双2,董子怡2,宋邑诚2,牛嗣云2(1. 河北大学附属医院 新生儿科,河北 保定 071000;2.河北大学 基础医学院,河北 保定 071000)摘 要:为了探讨齐墩果酸对衰老大鼠睾丸间质细胞的作用,采用MTT法确定齐墩果酸最适药物浓度,氧化应激创建大鼠睾丸间质细胞衰老模型,RT-qPCR、免疫荧光和免疫印迹检测胰岛素/胰岛素样生长因子1(insulin-like growth factor 1, IGF1)信号通路关键基因转录情况和蛋白翻译情况,采用INSR抑制剂处理细胞,流式细胞术检测细胞凋亡情况.结果显示:与正常组相比,INSR、IRS1、IRS2、IGF1的mRNA转录水平和蛋白翻译水平显著下降(P<0.05);IGFBP3的mRNA转录水平显著提高(P<0.05),免疫荧光和免疫印迹均未检测到此基因表达;与衰老组相比,齐墩果酸组明显逆转此现象(P<0.05);齐墩果酸能明显抑制衰老组细胞的凋亡(P<0.05),INSR抑制剂处理后,细胞凋亡率明显高于齐墩果酸组(P<0.05).综上可知,齐墩果酸通过调控胰岛素/IGF1信号通路关键基因的转录和翻译延缓Leydig细胞衰老.关键词:齐墩果酸;胰岛素/IGF1;衰老;睾丸间质细胞;RT-qPCR中图分类号:Q291 文献标志码:A 文章编号:1000-1565(2022)04-0403-08Effects of oleanolic acid on the expression of key genes of insulin/IGF1 pathway in leydig cells of aging ratsLI Shaohua1,2, NIU Shuang2, DONG Ziyi2,SONG Yicheng2, NIU Siyun2(1. Department of Neonatology, Affiliated Hospital of Hebei University, Baoding 071000, China;2. School of Basic Medical Sciences, Hebei University, Baoding 071000, China)Abstract: To investigate the effect of oleanolic acid on leydig cells of aging rats, the MTT method was used to determine the optimal drug concentration of oleanolic acid. The aging module of rat leydig cell was built according to the free radical oxidative damage method. Gene and protein expression of the key gene in the insulin/insulin-like growth factor 1(IGF1)signaling pathway was detected by RT-qPCR, immunofluorescence technique(IF), and Western blot. After treated with INSR inhibitor, cell apoptosis was performed by flow cytometry. The results showed that INSR, IRS1, IRS2 and IGF1 mRNA transcription level and protein expression level were significantly downregulated(P<0.05); IGFBP3 mRNA transcription level was significantly upregulated(P<0.05), otherwise, the expression could not be detected by IF and Western blot. Oleanolic acid reversed the above phenomenon, compared to aging group(P<0.05).- 收稿日期:2021-11-02 基金项目:国家自然科学基金资助项目(81673714);河北省中医药管理局科研项目(2016204;20200234);河北大学研究生创新资助项目(HBU2021ss025) 第一作者:李少华(1980—),女,河北定州人,河北大学附属医院主管护师,主要从事生殖衰老方向研究. E-mail:xiaolizhu2007@163.com 通信作者:牛嗣云(1967—),女,河北承德人,河北大学教授,博士,博士生导师,主要从事生殖衰老方向研究.E-mail: nsy1688@163.com第4期李少华等:齐墩果酸对衰老大鼠睾丸间质细胞胰岛素/IGF1通路关键基因表达的影响Oleanolic acid can delay cell apoptosis in the aging group(P<0.05). It was found that cell apoptosis rate was significantly higher than oleanolic acid group(P<0.05)after treated with INSR inhibitor. In summary, oleanolic acid delays leydig cell senescence by regulating insulin/IGF1 signaling pathway essential gene expression and transcripts. Reference | Related Articles | Metrics | Comments（0）

Select

A class of linear codes from Weil sums LU Hong, YANG Shudi, ZHANG Tonghui Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 350-357.   DOI: 10.3969/j.issn.1000-1565.2022.04.003 Abstract （274）      PDF（pc） （385KB）（154）       Knowledge map    Save It is of vital significance to explore the weight distributions of linear codes with a few weights in coding theory. By selecting an appropriate defining set, a new class of two-weight or three-weight linear codes is constructed. Then, their weight distributions are determined by employing exponential sums over finite fields. Furthermore, some examples to verify the correctness of our results were gived and some of them are optimal codes with respect to the Griesmer bound. Reference | Related Articles | Metrics | Comments（0）

Select

Stability of set-valued integral differential equations with fractional-like Hukuhara derivatives WANG Peiguang, BI Jiahui, BAO Junyan Journal of Hebei University(Natural Science Edition)    2023, 43 (1): 1-8.   DOI: 10.3969/j.issn.1000-1565.2023.01.001 Abstract （208）      PDF（pc） （389KB）（154）       Knowledge map    Save The stability of set-valued integral differential equations with fractional-like Hukuhara derivatives was investigated. The criteria of equistability, uniform stability, equiasymptotic stability and strictly stability of the solutions are obtained by using Lyapunov-like functions and the new comparison principle. Reference | Related Articles | Metrics | Comments（0）

Select

A new record of the genus Hesperus from China(Coleoptera: Staphylinidae) XU Wang, ZENG Qinghuai, TANG rong, CAI Yujie Journal of Hebei University(Natural Science Edition)    2022, 42 (4): 421-423.   DOI: 10.3969/j.issn.1000-1565.2022.04.012 Abstract （272）      PDF（pc） （482KB）（153）       Knowledge map    Save In a survey of rove beetles in Wutongshan Nature Reserve of Guangdong Province, a new record species was reported from China: Hesperus laevigatus Fauvel, 1895. The diagnostic characteristics and adult habitus of this species is described and illustrated in this paper. Reference | Related Articles | Metrics | Comments（0）

Select

Classroom personnel detection based on object detection and time series migration CONG Shuai,YANG Lei,HUA Zhenghao,YANG Xiaohui Journal of Hebei University(Natural Science Edition)    2023, 43 (4): 432-441.   DOI: 10.3969/j.issn.1000-1565.2023.04.012 Abstract （147）      PDF（pc） （1826KB）（151）       Knowledge map    Save In order to solve the problem of efficient supervision and management and data analysis of classroom persons in the intelligent reconstruction of education, this paper combines the good characteristics of single-stage object detection algorithm and the good special extraction ability of convolutional neural networks(CNN), and proposes an improved YOLO object detection algorithm based on attention network and time series migration. Firstly, this paper performs frame-by-frame extraction and non-distortion image deflation on the source video stream, and performs image super-resolution processing- DOI:10.3969/j.issn.1000-1565.2023.04.012基于目标检测和迁移时间序列的教室人员检测丛帅1,杨磊2,华征豪3,杨晓晖2(1.河北大学 工商学院,河北 保定 071000;2.河北大学 教务处,河北 保定 071002;3.河北大学 网络空间安全与计算机学院,河北 保定 071000)摘 要:为了解决教育智能化重构中对于教室人员的高效监督管理和数据分析,结合单阶段目标检测算法的优良特性和卷积神经网络(convolutional neural networks,CNN)良好的特征提取能力,提出了一种基于注意力机制网络和迁移时间序列改进YOLO目标检测算法的教室人员目标检测算法.首先,对源视频流进行逐帧抽取和非畸变的图像放缩,通过生成对抗网络(generative adversarial network,GAN)进行图像超分辨处理;其次,对每帧图像进行多尺度采样和初步目标检测;然后,根据不同尺度得到的候选结果进行非极大抑制(non maximum suppression,NMS)以去除置信度较低的个体;之后,对候选结果进行融合,再使用交并比(intersection over union,IoU)进行重叠度计算以更新数据、去除重合或过于紧密的定位位置,然后将当前帧的检测结果与先前时间区间中的检测结果作为时间序列进行统计学数据迁移融合(time series migration,TSM)获得最后的检测结果.实验结果表明,本文方法不仅有效地提升了教室人员目标检测的准确率,并且可以进行实时检测.关键词:目标检测;多尺度图像特征;超分辨率;注意力机制网络;迁移时间序列中图分类号:TP391.41 文献标志码:A 文章编号:1000-1565(2023)04-0432-10Classroom personnel detection based onobject detection and time series migrationCONG Shuai1,YANG Lei2,HUA Zhenghao3,YANG Xiaohui2(1. Industrial and Commercial College, Hebei University, Baoding 071000, China;2. Office of Educational Administration, Hebei University, Baoding 071002, China;3. School of Cyber Security and Computer, Hebei University, Baoding 071000, China )Abstract: In order to solve the problem of efficient supervision and management and data analysis of classroom persons in the intelligent reconstruction of education, this paper combines the good characteristics of single-stage object detection algorithm and the good special extraction ability of convolutional neural networks(CNN), and proposes an improved YOLO object detection algorithm based on attention network and time series migration. Firstly, this paper performs frame-by-frame extraction and non-distortion image deflation on the source video stream, and performs image super-resolution processing- 收稿日期:2022-09-13 基金项目:国家自然科学基金面上项目(62172139);中国高校产学研创新基金资助项目(2021BCF03002) 第一作者:丛帅(1980—),男,河北保定人,河北大学工商学院讲师,主要从事大数据技术、图像处理方面研究.E-mail:congshuai@hbu.cn 通信作者:杨磊(1986—),男,河北保定人,河北大学助理研究员,主要从事教育技术、智慧教学方面研究.E-mail:403064340@qq.com第4期丛帅等:基于目标检测和迁移时间序列的教室人员检测by Generative Adversarial Network(GAN). Secondly, multi-scale sampling and preliminary object detection are performed for each frame, and then Non Maximum Suppression(NMS)is performed to remove the individuals with low confidence based on the candidate results obtained at different scales. Then, the candidate results are fused, and the overlap is calculated using intersection over union(IoU)to update the data and remove overlapping or too close localization locations. Finally, the detection results of the current frame and those of the previous time interval are used as a time series for statistal data migration to obtain the final detection results. The experimental results show that this method not only effectively improves the accuracy of classroom personnel target detection, but also enables real-time detection. Reference | Related Articles | Metrics | Comments（0）

Select

Carbon-coated K0.5Mn2O4.3·0.5H2O as cathode for potassium-ion batteries QIAN Jiaqi, LI Xiaoting, LEI Yu, ZHANG Wenming Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 494-500.   DOI: 10.3969/j.issn.1000-1565.2022.05.007 Abstract （251）      PDF（pc） （1344KB）（149）       Knowledge map    Save Manganese oxide-based cathodes are attracting great interest owing to their advantages such as low cost, high capacity and energy density. Nevertheless, rapid capacity fading is a critical problem due to the direct contact between cathode and electrolyte, restraining its wide applications. To solve this problem, surface coating becomes a feasible strategy for the cathode material. A carbon coating layer with dopamine was introduced uniformly on the surface of K0.5Mn2O4.3·0.5H2O by solvothermal process. The coated carbon layer prohibits direct contact of electrode and the electrolyte to effectively hinders side reaction. At a current density of 50 mA/g, the discharge capacity of carbon-coated sample with 10%(wt.)dopamine(C@S-KMO-10%)is still as high as 89.8 mA·h/g with a capacity retention ratio of 63.4% after 100 cycles, showing improved cycling stability and superior rate capability. While the uncoated sample(S-KMO)delivers a discharge capacity of 68.8 mA·h/g - DOI:10.3969/j.issn.1000-1565.2022.05.007碳包覆钾离子电池正极材料K0.5Mn2O4.3·0.5H2O的研究钱佳琦1,李小亭1,雷宇2,张文明2(1.河北大学 质量技术监督学院,河北 保定 071002;2.河北大学 物理科学与技术学院,河北 保定 071002)摘 要:锰基氧化物正极材料具有低成本、高容量和高能量密度等优点,是钾离子电池正极材料研究的热点.然而,由于正极材料与电解液直接接触,发生副反应,导致容量迅速衰减,限制了它的广泛应用.为解决这一问题,对正极材料采用表面包覆的改性策略,以多巴胺为碳源,采用溶剂热法在K0.5Mn2O4.3·0.5H2O正极材料均匀地包覆碳涂层.碳包覆层阻止了正极材料与电解液的直接接触,有效地抑制了副反应.结果发现:在电流密度为50 mA/g的条件下,添加占正极材料质量10%的多巴胺时,放电容量为89.8 mA·h/g,容量保持率为63.4%,表现出优异的电化学性能,而未包覆的正极材料的放电容量为68.8 mA·h/g, 循环100圈后容量保持率为32%.这种表面涂层策略为提高钾离子电池阴极的循环稳定性提供了一种新的改性方法.关键词:溶剂热法;碳包覆;正极材料;表面改性中图分类号:O646 文献标志码:A 文章编号:1000-1565(2022)05-0494-07Carbon-coated K0.5Mn2O4.3·0.5H2O as cathode for potassium-ion batteriesQIAN Jiaqi1, LI Xiaoting1, LEI Yu2, ZHANG Wenming2(1. College of Quality and Technical Supervision, Hebei University, Baoding 071002, China;2. College of Physics Science and Technology, Hebei University, Baoding 071002, China)Abstract: Manganese oxide-based cathodes are attracting great interest owing to their advantages such as low cost, high capacity and energy density. Nevertheless, rapid capacity fading is a critical problem due to the direct contact between cathode and electrolyte, restraining its wide applications. To solve this problem, surface coating becomes a feasible strategy for the cathode material. A carbon coating layer with dopamine was introduced uniformly on the surface of K0.5Mn2O4.3·0.5H2O by solvothermal process. The coated carbon layer prohibits direct contact of electrode and the electrolyte to effectively hinders side reaction. At a current density of 50 mA/g, the discharge capacity of carbon-coated sample with 10%(wt.)dopamine(C@S-KMO-10%)is still as high as 89.8 mA·h/g with a capacity retention ratio of 63.4% after 100 cycles, showing improved cycling stability and superior rate capability. While the uncoated sample(S-KMO)delivers a discharge capacity of 68.8 mA·h/g - 收稿日期:2022-03-09 基金项目:国家自然科学基金资助项目(52171206) 第一作者:钱佳琦(1995—),女,河北保定人,河北大学在读硕士研究生,主要从事钾离子电池正极材料方向研究. E-mail:qianjiaqi6953@163.com 通信作者:张文明(1982—),男,吉林四平人,河北大学教授,主要从事新型离子电池、电催化锌空气电池、微生物燃料电池、可穿戴柔性传感器件方向研究.E-mail:wmzhang@hbu.edu.cn第5期钱佳琦等:碳包覆钾离子电池正极材料K0.5Mn2O4.3·0.5H2O的研究with 32% capacity retention after 100 cycles. This surface coating strategy offers a new modification approach to improve the cycling stability of cathodes for potassium ion batteries. Reference | Related Articles | Metrics | Comments（0）

Select

Comparison of application of assemblers in phylogenomics WANG Yaozhuo, ZHANG Wenqiang, ZHANG Junxia Journal of Hebei University(Natural Science Edition)    2023, 43 (2): 171-178.   DOI: 10.3969/j.issn.1000-1565.2023.02.009 Abstract （232）      PDF（pc） （1187KB）（146）       Knowledge map    Save To select the most suitable assembler for ultra-conserved elements(UCE)phylogenomic practice, five different assembly softwares, SPAdes, ABySS, Velvet, Trinity and Minia were applied, to assemble 17 UCE captured sequencing libraries, respectively. The results showed that among the five assemblers, Trinity consumed significantly longer computational time than the others; SPAdes and Trinity both assembled more contigs and obtained more longer contigs(> 250 bp)than the other three assemblers, but SPAdes captured the highest number of UCE loci. Therefore, SPAdes is more suitable for the assembly of UCE data than the other assembly softwares. This study provides a technical reference for the practice of UCE-based phylogenomic studies. Reference | Related Articles | Metrics | Comments（0）

Select

Segmentation algorithm of brain tumor MR images based on receptor field amplification and attentional mechanism ZHENG Wei, ZHAO Jinfang, ZHANG Yijing, LIU Shuaiqi, ZHANG Xiaodan, MA Zepeng Journal of Hebei University(Natural Science Edition)    2022, 42 (5): 542-551.   DOI: 10.3969/j.issn.1000-1565.2022.05.013 Abstract （335）      PDF（pc） （1558KB）（142）       Knowledge map    Save Although the current full convolutional neural network has been able to accurately identify the location of brain tumors in the brain tumor segmentation task, there are still problems of low segmentation accuracy due to limited receptive field and information loss. To solve these problems, this paper proposes a U-Net brain tumor MR image segmentation algorithm based on receptive field amplification and attentional mechanism. Firstly, the receptive field block(RFB)is introduced into the U-Net network to increase the receptive field of the network, which solves the problem of low segmentation accuracy caused by the limited receptive field. In addition, an efficient channel attention module(ECA)is introduced to increase the networks response to useful features and suppress redundant features in the network. The MR brain tumor image data provided by the BRATS(the brain tumor image segmentation- DOI:10.3969/j.issn.1000-1565.2022.05.013基于感受野扩增和注意力机制的U-Net脑肿瘤MR图像分割郑伟1,赵金芳1,张奕婧1,刘帅奇1,张晓丹2,马泽鹏2(1. 河北大学 电子信息工程学院,河北 保定 071002;2. 河北大学附属医院 超声诊断科,河北 保定 071000)摘 要:针对U-Net网络感受野受限以及信息丢失导致的分割精度低的问题,提出了一种基于感受野扩增和注意力机制的U-Net脑肿瘤MR图像分割算法.首先,在U-Net网络中引入感受野模块(receptive field block,RFB)来增大网络的感受野,解决了网络由于感受野受限带来的分割精度低的问题.此外在网络中引入有效的通道注意模块(efficient channel attention,ECA)来增加网络对有用特征的响应,抑制网络中的冗余特征.使用BraTS(the brain tumor image segmentation challenge)提供的脑肿瘤MR图像数据对本文算法进行测试,用Dice相似性系数等指标进行评价,结果显示在完整肿瘤、核心肿瘤以及增强肿瘤的Dice值分别可达到0.86、0.86、0.79.与U-Net模型以及其他的网络相比得到了提高.实验结果表明,本文提出的算法能够有效提升脑肿瘤分割的精度,具有良好的分割性能.关键词:脑肿瘤分割;U-Net;RFB;注意力机制 中图分类号:TN911 文献标志码:A 文章编号:1000-1565(2022)05-0542-10Segmentation algorithm of brain tumor MR images based on receptor field amplification and attentional mechanismZHENG Wei1, ZHAO Jinfang1, ZHANG Yijing1, LIU Shuaiqi1, ZHANG Xiaodan2, MA Zepeng2(1. College of Electronic and Information Engineering, Hebei University, Baoding 071002, China; 2. Department of Ultrasonography, Affilicated Hospital of Hebei University, Baoding 071000, China )Abstract: Although the current full convolutional neural network has been able to accurately identify the location of brain tumors in the brain tumor segmentation task, there are still problems of low segmentation accuracy due to limited receptive field and information loss. To solve these problems, this paper proposes a U-Net brain tumor MR image segmentation algorithm based on receptive field amplification and attentional mechanism. Firstly, the receptive field block(RFB)is introduced into the U-Net network to increase the receptive field of the network, which solves the problem of low segmentation accuracy caused by the limited receptive field. In addition, an efficient channel attention module(ECA)is introduced to increase the networks response to useful features and suppress redundant features in the network. The MR brain tumor image data provided by the BRATS(the brain tumor image segmentation- 收稿日期:2021-06-11 基金项目:河北省自然科学基金资助项目(F2020201025;H2020201021);河北省高等学校科学技术研究项目(BJ2020030) 第一作者:郑伟(1972—),女,黑龙江兰西人,河北大学教授,博士,主要从事图像处理与分析、图像安全通信、图像加密和隐藏方向研究.E-mail:147685650@qq.com 通信作者:张晓丹(1989—),女,河北承德人,河北大学附属医院主治医师,主要从事常规疾病及肿瘤病变的影像诊断.E-mail:zxd201505@126.com第5期郑伟等:基于感受野扩增和注意力机制的U-Net脑肿瘤MR图像分割challenge)was used to test the method, and indexes such as Dice similarity coefficient were used to evaluate the method. The results showed that the Dice of intact tumor, core tumor and enhanced tumor could reach 0.86, 0.86 and 0.79 respectively. Compared with the U-Net model and other networks, this method is improved. The results show that the proposed method can effectively improve the accuracy of brain tumor segmentation and has good segmentation performance. Reference | Related Articles | Metrics | Comments（0）

Select

Residents electric larceny detection based on Pearson correlation coefficient and SVM GUO Liang,GUO Zixue,JIA Hongtao,FAN Ruoyu Journal of Hebei University(Natural Science Edition)    2023, 43 (4): 357-363.   DOI: 10.3969/j.issn.1000-1565.2023.04.003 Abstract （137）      PDF（pc） （914KB）（136）       Knowledge map    Save The exist of residents electric larceny not only damages the economic benefits of power supply enterprises, but also affects the security of electric grid. With the rapid development of China’s digital economy and the improvement of electric acquisition system, electric larceny detected methods which are based on big data are updating constantly. The paper puts forward a new method which combines Pearson correlation coefficient, SMOTE algorithm and SVM. Firstly, the paper uses Pearson correlation coefficient to collect abnormal users’ effective power stealing data which are recorded, then SMOTE algorithm is used to enrich effective power stealing database. At last the paper builds a detection mathematical model based on the data base by SVM. By comparing the results of detection mathematical model and the reality situation of users, the validity and feasibility of the method is proved. The new method not only gives a new thought for electricity anti-stealing in power enterprises, but also improves the efficient of working team. Reference | Related Articles | Metrics | Comments（0）

Select

Progress in identifying the animal reservoirs of monkeypox virus GENG Yansheng, XIA Zihan, SHI Tengfei, CAO Zhiran Journal of Hebei University(Natural Science Edition)    2023, 43 (3): 303-309.   DOI: 10.3969/j.issn.1000-1565.2023.03.011 Abstract （155）      PDF（pc） （491KB）（135）       Knowledge map    Save Monkeypox is a zoonotic disease caused by monkeypox virus(MPXV). The recent multi-country monkeypox outbreak in non-endemic regions has been a public health emergency of international concern. To understand the potential host sources and transmission routes of MPXV, this article reviewed the MPXV infection and prevalence in wild animals, as well as the susceptibility of wild and captive animals to MPXV. The possible animal hosts and the “animal-human” transmission risk of MPXV were also discussed. The review provides a reference for the human and animal public health departments to jointly develop effective measures to control the monkeypox epidemic. Reference | Related Articles | Metrics | Comments（0）